2015
DOI: 10.14233/ajchem.2015.18871
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Metal Complexes of Ceftriaxone as Potent Medication Against Ailment

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“…Butyrylcholine esterase inhibitory activity was measured by spectrophotometric method reported previously. 27 The reaction mixture contained 120 ml PBS buffer (pH 7.4), 10 ml butyrylcholinesterase solution, 10 ml of test compound solution, which were mixed and incubated for 10 min (37 C). The reaction was initiated by the addition of 30 ml S-butyrylthiocholine chloride and 30 ml DTBN.…”
Section: Bioassaymentioning
confidence: 99%
“…Butyrylcholine esterase inhibitory activity was measured by spectrophotometric method reported previously. 27 The reaction mixture contained 120 ml PBS buffer (pH 7.4), 10 ml butyrylcholinesterase solution, 10 ml of test compound solution, which were mixed and incubated for 10 min (37 C). The reaction was initiated by the addition of 30 ml S-butyrylthiocholine chloride and 30 ml DTBN.…”
Section: Bioassaymentioning
confidence: 99%
“…From the detailed literature survey on condensed heterocyclic ring systems, it is evident that indenopyrazoles have also played a significant role due to their wide biological activities, viz., analgesics, antitubercular, antiinflammatory agents, etc. An huge literature revealed that organotin(IV) complexes appeared as biologically potent moieties having antitumor [11,12], antitubercular [13][14][15], antifertility [16,17], antimicrobial [18][19][20], antiviral [21], antinematicidal, antiinsecticidal [22], antilieshmanial [23], anti-inflammatory [24], antidiabetic [25], antihypertensive [26], antioxidant [27], antimalarial [28] activity, etc. The bioactive metal complexes have enormous chemotherapeutic importance due to their ability to bind and degrade DNA of the microorganisms [29][30][31][32][33].…”
mentioning
confidence: 99%