“…Metabolomic profiles of numerous hepatotoxins in laboratory animals have been described, and include hydrazine [117], bromobenzene [118, 119], methapyrilene [120], methylenedianiline [121], D-galactosamine [121–123], clofibrate [121], allyl formate [124], the anti-HBV compound Bay41-4109 [125], paracetamol [126–133], isoniazid [134, 135], carbon tetrachloride [131, 136–138], α-naphthylisothiocyanate [137], perfluorododecanoic acid [139], valproate [140], Huang-yao-zi [141], dimethylnitrosamine [142], polychlorinated biphenyls [143, 144], 2,3,7,8-tetrachlorodibenzo- p -dioxin [143], methamphetamine [145], (+)-usnic acid [146], pentamethychromanol [147] and methotrexate [131]. Detailed analysis of these drug-induced liver injury (DILI) studies falls beyond the scope of this review.…”