Metabolic syndrome and quality of life (QOL) using generalised and obesity-specific QOL scales

Han, Jeehae; Park, Hae‐Sim; Shin, Chol; Chang, Hyo Won; Yun, Kyoung-In; Cho, S. H.; Choi, Eun Young; Lee, S. Y.; Kim, J. H.; Sung, Hyoju; Choi, Soo In; Yoon, Yeong Sook; Lee, E. S.; Song, Hongsun; Bae, Sang‐Cheol

doi:10.1111/j.1742-1241.2009.02021.x

Cited by 52 publications

(65 citation statements)

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“…These findings confront the results of most studies, which support the idea that MetS would be significantly associated with worse QOL [5][6][7][8][9][10][11][12][13]15], even though they corroborate the findings of some studies [26,27,40] which did not find significant association between MetS and QOL after adjustments for confounding factors. It is noteworthy that different QOL assessment instruments had been used in those studies.…”

Section: Discussionsupporting

confidence: 64%

Association between metabolic syndrome and quality of life

Saboya

Bodanese²,

Zimmermann³

et al. 2016

Sci Med

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Aims: Despite all progress made in understanding and treating metabolic syndrome, the study of its impact on quality of life is still controversial and not well understood. The aim of this study was to test the hypothesis that metabolic syndrome can be associated with a worse quality of life. Methods: A controlled cross-sectional study included individuals with metabolic syndrome, from the sub-analysis of a randomized clinical trial about lifestyle modification and cardiovascular risk factors, as well as individuals with no metabolic syndrome, attended as outpatients in several clinics at a general university hospital in Southern Brazil. Measurements were made in individual interviews and included data collection, laboratory tests, and application of general scales such as Mini-Mental State Examination and Medical Outcomes Study Short Form, General Health Survey (SF-36). Comparisons of quantitative data used the Student's t test, followed by analysis of covariance or multiple linear regression for adjustment, and correlation coefficient. For categorical data, the Chi-square or Fisher's exact test were used. Results: The study included 229 individuals, 118 metabolic syndrome and 111 no metabolic syndrome. In univariate analysis, metabolic syndrome was significantly associated with lower scores in the social functioning (p<0.001) and role emotional (p=0.019) quality of life domains, and with the Mental Component Summary score of the SF-36 (p=0.013). However, after adjustments for confounding factors, especially body mass index, the significance of these associations was lost. The only significant association between metabolic syndrome and quality of life that has remained after the adjustments was with worse QOL in the role emotional domain, but only in men (p=0.049). Conclusions: After adjusting for multiple variables, metabolic syndrome was significantly associated with decreased quality of life scores in men in the role emotional domain.Key woRds: metabolic syndrome X; risk factors; quality of life.RESuMO objetivos: Apesar dos avanços no entendimento e tratamento da síndrome metabólica, o estudo do seu impacto sobre a qualidade de vida é ainda controverso e inconclusivo. O objetivo deste estudo foi testar a hipótese de que a síndrome metabólica estaria associada à piora da qualidade de vida. Métodos: Um estudo transversal controlado incluiu indivíduos com síndrome metabólica, advindos da subanálise de um estudo controlado randomizado sobre modificação de estilo de vida e fatores de risco cardiovascular; e indivíduos sem síndrome metabólica, provenientes de diversos ambulatórios de um hospital geral no sul do Brasil. As medidas foram realizadas em entrevistas individuais, que incluíram coleta de dados demográficos, testes laboratoriais e aplicação do Exame do Estado Mental e o Medical Outcome Study Short Form, General Health Survey (SF-36). Para comparações entre dados quantitativos, foram utilizados teste t de Student, análise de covariância ou regressão linear múltipla para os ajustes dos fatores confu...

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Section: Discussionsupporting

confidence: 64%

Association between metabolic syndrome and quality of life

Saboya

Bodanese²,

Zimmermann³

et al. 2016

Sci Med

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“…Many studies have proven that the quality of sexual life is a determining factor in the overall quality of life (11). However, even today, it is not clear whether or not obesity is an independent risk factor in the quality of female sexual life (12).…”

Section: Discussionmentioning

confidence: 99%

The effect of body mass index on the sexual functions of morbidly obese female patients

Erbay¹,

Özlü²,

Şahin³

et al. 2017

Dusunen Adam

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The effect of body mass index on the sexual functions of morbidly obese female patientsObjective: The aim of this study is to investigate whether morbidly obese female patients are suffering sexual dysfunction, in addition to analyzing the effect of body mass index (BMI) on sexual functions. Method: A total of 72 morbidly obese women admitted to the Endocrinology Department, whose BMI scores were 40 or over, and 28 healthy women age-matched with the morbidly obese group, whose BMI scores were under 30 were included in this study. Considering the effects on sexual functioning, the patients and the control group were evaluated by a psychiatric specialist. women with a psychiatric disorder according to DSM-5, taking medicines that could affect sexual functions, and those with a chronic physical or any neurological disease or being pregnant or breastfeeding were excluded from the study. A sociodemographic data form and the Arizona Sexual Experiences Scale (ASEX) were administered to both the treatment and control group. Results: Statistical analyses revealed that morbidly obese female patients more frequently suffered from sexual dysfunction compared to the control group. The Arizona Sexual Experiences Scale (ASEX) and all subscale scores except the sexual satisfaction rate were significantly higher in morbidly obese female patients than in the control group. There was no correlation found between the BMI and sexual function in the analyses conducted. Conclusion: In our study, morbidly obese female patients were found to show more impairments in all areas of sexual functions except sexual satisfaction rate when compared to the control group. Previous studies have suggested that obesity is the cause of sexual dysfunction in men; however, the same relationship could not be demonstrated in women. In a limited study of female patients, conflicting results were attributed to the inability to control variables. The fact that variables such as depression, anxiety, and chronic physical illness, which may affect sexual function, had been assessed in our study is important for accurately interpreting the findings. The data in our study reveals the importance of investigating sexual functions in morbidly obese female patients. Keywords: Arizona Sexual Experiences Scale, morbid obesity, sexual dysfunctions ÖZET Morbid obez kadın hastalarda vücut kitle indeksinin cinsel işlevler üzerine etkisiAmaç: Bu çalışmanın amacı morbid obez kadın hastalarda cinsel işlev bozukluğu olup olmadığının araştırılması ve vücut kitle indeksinin (VKİ) cinsel işlevler üzerine etkisinin incelenmesidir. Yöntem: Bu çalışmaya İnönü Üniversitesi Tıp Fakültesi Endokrinoloji Bilim Dalı'na başvuran ve VKİ'si en az 40 olan 72 kadın morbid obezite hastası ve bu hastalarla yaş olarak eşleştirilmiş VKİ'si 30'un altında olan 28 sağlıklı kadın dâhil edilmiştir. Cinsel işlevleri etkileyebildiği bilindiğinden hasta ve kontrol grubu bir psikiyatri uzmanı tarafından değerlendirilerek DSM 5'e göre bir psikiyatrik hastalığı olanlar, cinsel işlevleri etkileyebile...

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“…101,102 As mentioned earlier, sarcopenia and obesity often coexist and that a loss of muscle mass could be related to impaired metabolism (such as insulin resistance and metabolic syndrome), 68,70 both of which may have negative effects on quality of life. 103,104 Sarcopenia is also significantly associated with ADL/instrumental activities of daily living (IADL) impairments, 51,105,106 which have been demonstrated to be strong predisposing factors of poor quality of life. 107 There is also evidence that ADL impairments are associated depression, loneliness, and social isolation, 108,109 which are also risk factors of poor quality of life.…”

Section: Potential Links Between Sarcopenia and Reduced Quality Of Lifementioning

confidence: 99%

Management of Sarcopenia to Improve Quality of Life in Geriatric Populations

Zhu²,

Chan³

et al. 2016

Clinical Medicine Insights: Geriatrics

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Sarcopenia, characterized by a progressive loss of skeletal muscle mass and strength that occurs with advancing age, has been associated with falls, fracture, disability, and mortality. Depending on the definitions used, the prevalence in 60-to 80-year old population is reported as 0.9%-35.9%, while the prevalence ranges from 7%-70.0% in people older than 80 years. Sarcopenia has been associated with lower quality of life. Well-designed exercise interventions, particularly resistance training as well as nutritional supplementation, have been proved to improve muscle strength and performance in geriatric populations. Resistance training may also enhance quality of life. However, there are limited data on the effects of nutritional supplementation as an intervention on quality of life among individuals with sarcopenia. This review briefly summarizes the relationship between sarcopenia and quality of life and presents the potential of interventions to improve muscle quality, physical performance, and quality of life. ACADEMIC EDITOR: atsushi sakuraba, editor in Chief PEER REVIEW: three peer reviewers contributed to the peer review report. Reviewers' reports totaled 497 words, excluding any confidential comments to the academic editor.FUNDING: authors disclose no external funding sources. COMPETING INTERESTS: Authors disclose no potential conflicts of interest.COPYRIGHT: © the authors, publisher and licensee libertas academica limited.this is an open-access article distributed under the terms of the Creative Commons CC-BY-nC 3.0 license. CORRESPONDENCE: rubyyu@cuhk.edu.hkPaper subject to independent expert single-blind peer review. all editorial decisions made by independent academic editor. Upon submission manuscript was subject to anti-plagiarism scanning. Prior to publication all authors have given signed confirmation of agreement to article publication and compliance with all applicable ethical and legal requirements, including the accuracy of author and contributor information, disclosure of competing interests and funding sources, compliance with ethical requirements relating to human and animal study participants, and compliance with any copyright requirements of third parties. this journal is a member of the Committee on Publication ethics (COPe).Provenance: the authors were invited to submit this paper.Published by libertas academica. learn more about this journal. SarcopeniaSarcopenia, defined as a geriatric syndrome characterized by a progressive loss of skeletal muscle mass and strength that occurs with advancing age, was first introduced by Rosenberg in 1989.1,2 The decline in muscle mass occurs after the age of 30 years.3,4 After the age of 50 years, muscle mass is reported to decline at an annual rate of approximately 0.2%; 5 after 70 years, the decline may accelerate to 0.6%-1% per year. [6][7][8] Over the past few decades, refining the definition of sarcopenia has led to significant variation in the meaning. Initially, the definition consists of the measurement of appendicular mass divided...

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Metabolic syndrome and quality of life (QOL) using generalised and obesity-specific QOL scales

Cited by 52 publications

References 32 publications

Association between metabolic syndrome and quality of life

Association between metabolic syndrome and quality of life

The effect of body mass index on the sexual functions of morbidly obese female patients

Management of Sarcopenia to Improve Quality of Life in Geriatric Populations

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