Metabolic Study of Dioecy in <scp><i>Mauritia flexuosa</i></scp>: NMR‐based and Chemometric Approaches

Freitas, Deisy dos Santos; Alcantara, Glaucia Braz

doi:10.1002/pca.2745

Cited by 3 publications

(3 citation statements)

References 19 publications

(20 reference statements)

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“…People consider it an important source of bioactive compounds. The carotenoid content for M. flexuosa L. pulp has been previously reported, wherein β-carotene is generally higher in this fruit than in carrot and spinach (dos Santos Freitas and Alcantara, 2018;Dos Santos et al, 2015;Freitas et al, 2018;Lescano et al, 2018). It also has a high content of lipids, proteins, carbohydrates, tannins, phenols, flavonoids, fiber, iron, copper and potassium (Koolen et al, 2013;Leão et al, 2017;Lescano et al, 2018;Nobre et al, 2018).…”

Section: Introductionmentioning

confidence: 53%

Bioactive compounds, phenolic profile, antioxidant capacity and effectiveness against lipid peroxidation of cell membranes of Mauritia flexuosa L. fruit extracts from three biomes in the Ecuadorian Amazon

Abreu-Naranjo

Paredes-Moreta

Granda-Albuja

et al. 2020

Heliyon

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The bioactive compounds, total antioxidant capacity and protective effect against lipid oxidative damage of red blood cell (RBC) membranes of Mauritia flexuosa L. extracts from three altitude levels (low, middle and high zones) were analyzed. The identification of the main polyphenols in the fruit was performed using High Performance Liquid Chromatography/Electrospray Ionization Tandem Mass Spectrometry analysis, while High-Performance Liquid Chromatography - Diode Array Detector was applied for the vitamin C and carotenoid analysis. The ability of the extracts (methanolic, free polyphenols and bound polyphenols) to protect RBC membranes against oxidative destruction was assessed utilizing the thiobarbituric acid reactive substance assay (TBARS) assay. Among the 14 phenolic compounds identified, quercetin glycosides were the most predominant ones. The fruit from the middle altitude zone showed higher vitamin C and lutein contents than those from the low and high areas, whilst higher values of β -Carotene were obtained in M. flexuosa L. from the low zone. The contents of flavonoids and total polyphenols were lower in fruit from the low zone, whilst the fruit from the middle zone had the highest values. Similar results were observed in the results of the antioxidant capacity assays. However, a significant difference was not found in the protective effect of the extracts from the three altitude zones against lipid peroxidation in RBC membranes.

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Section: Introductionmentioning

confidence: 53%

Bioactive compounds, phenolic profile, antioxidant capacity and effectiveness against lipid peroxidation of cell membranes of Mauritia flexuosa L. fruit extracts from three biomes in the Ecuadorian Amazon

Abreu-Naranjo

Paredes-Moreta

Granda-Albuja

et al. 2020

Heliyon

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“…Moreover, only the groups treated For the phytochemical analysis, female Antidesma bunius leaves showed positive results for all the constituents analyzed, except for anthraquinones, alkaloids and flavonoids while male Antidesma bunius leaves showed positive results in the tests done for the presence of saponins, steroids, phlobatannins, tannins and polyphenols (Table 3). Although several studies have compared the individual secondary metabolites between other dioecious species, such as in Mauritia flexuosa 15 , Tinospora cordifolia 16 , and Piper betle 17 , the in-depth comparison of A. bunius male and female leaves have not been done prior. Here, the results show through preliminary methods that terpenoids were present in detectable quantities in the female A. bunius samples compared to the male.…”

Section: Fig 4 Mean Body Weight Of Non-diabetic Control and Alloxan Induced-diabetic Mice Treated And Non-treated With Bignay Extracts (Nmentioning

confidence: 99%

“…Its effect on ethnopharmacology have been documented previously, wherein traditional healers in India would have gender preferences for their herbal medicines 14 . The effect of dioecy on secondary metabolites have been established for several plant species, such as Mauritia flexuosa 15 , Tinospora cordifolia 16 and Piper betle 17 . For A. bunius, however, such analyses and its correlation to bioactivity have not been reported yet.…”

Section: Introductionmentioning

confidence: 99%

In Vivo Hypoglycemic Activities of Male and Female Antidesma Bunius (L.) Spreng. in Alloxan-Induced Diabetic Mice

et al. 2019

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Diabetes mellitus, a complex chronic disease that is associated with hyperglycemia (high blood sugar) affects millions of people worldwide. This study evaluated the hypoglycemic activities of male and female Antidesma bunius, commonly known as currant tree or bignay, extracts in alloxan-treated ICR mice. In addition, the effects of the treatments on blood urea nitrogen (BUN) and creatinine levels were determined. Phytochemical screening using standard protocol was performed. Plant extracts (500 mg/kg) were administered orally via gavage for 14 days and fasting blood glucose (FBG) levels were monitored prior to alloxan-induction on the day of alloxan-induction, and on the 3rd, 7th and 14th days of treatment. Sera were collected on the 14th day to measure the BUN and creatinine levels. Phytochemical screening was performed using standard TLC spray tests. All extracts were found to significantly lower FBG levels compared to the positive (glibenclamide 10 mg/kg) and negative (distilled water) controls (One-way ANOVA, p-value<0.0001). The most active extract, aqueous male A. bunius extract, significantly lowered FBG levels by as much as 61.26±17.89% after the 14th day (paired t-test, p-value = 0.0211). Both BUN and creatinine values were found to be significantly different in the treated mice compared to the controls (One-way ANOVA, p-value = 0.0005 and 0.000479, respectively). The BUN level of all mice was still within normal range, unlike with the creatinine level where only the female and male aqueous A. bunius and female ethanolic A. bunius extracts were within normal range. Phytochemical screening showed the presence of saponins, tannins, and polyphenols, phlobatannins, steroids and terpenoids. This study demonstrates the potential of male and female A. bunius leaf extracts to reduce fasting blood glucose levels. Additional work, pertaining to the identification of possible bioactive compounds and establishing the mechanisms thereof, could be performed.

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Improvement of the bioaccessibility of bioactive compounds from Amazon fruits treated using high energy ultrasound

Carvalho

Lemos

Sanches

et al. 2020

Ultrasonics Sonochemistry

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Metabolic Study of Dioecy in Mauritia flexuosa: NMR‐based and Chemometric Approaches

Cited by 3 publications

References 19 publications

Bioactive compounds, phenolic profile, antioxidant capacity and effectiveness against lipid peroxidation of cell membranes of Mauritia flexuosa L. fruit extracts from three biomes in the Ecuadorian Amazon

Bioactive compounds, phenolic profile, antioxidant capacity and effectiveness against lipid peroxidation of cell membranes of Mauritia flexuosa L. fruit extracts from three biomes in the Ecuadorian Amazon

In Vivo Hypoglycemic Activities of Male and Female Antidesma Bunius (L.) Spreng. in Alloxan-Induced Diabetic Mice

Improvement of the bioaccessibility of bioactive compounds from Amazon fruits treated using high energy ultrasound

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