Metabolic profiles and progesterone cycles in first lactation dairy cows

Taylor, Victoria; Beever, D. E.; Bryant, M. J.; Wathes, D C

doi:10.1016/s0093-691x(02)01225-6

Cited by 86 publications

(82 citation statements)

References 28 publications

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“…However, previous data indicate that IGF-I was higher in both dairy (Kawashima et al, 2007) and beef cows (Kawashima et al, 2008) that ovulated earlier in the postpartum. Moreover, β-hydroxybutyrate concentration did not change between Ov and Nov groups in the current study, in agreement with results from Kawashima et al (2008) in beef cattle, despite the observation by Taylor et al (2003) that dairy cows with delayed ovulation have higher β-hydroxybutyrate levels. Furthermore, there were no changes in the IGF-I and β-hydroxybutyrate concentrations before and after ovulation in the Ov group, contrasting with results from Kawashima et al (2007), who observed a reduction in IGF-I concentrations after ovulation in postpartum dairy cows. )…”

Section: Resultssupporting

confidence: 91%

“…Moreover, despite the higher plasmatic concentration of IGF-I in crossbred cows, hepatic IGF-I mRNA expression did not follow the same pattern. This contradiction could be due to the fact that plasmatic concentration of IGF-I is also correlated to the hepatic expression of IGF binding proteins 1-6 and to the IGF acid labile subunit (IGF ALS) (Fenwick et al, 2008), which regulates IGF-I plasma half-life and transport through the vascular endothelium (Thissen et al, 1994). Moreover, the decreased concentration of IGF-I in postpartum beef cows coincided with an increased concentration of circulating IGFBP-2 and decreased IGFBP-3 (Roberts et al, 1997).…”

Section: Discussionmentioning

confidence: 99%

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Insulin-like growth factor and growth hormone receptor in postpartum lactating beef cows

Schneider

Pfeifer²,

Hax³

et al. 2010

Pesq. agropec. bras.

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Section: Resultssupporting

confidence: 91%

Section: Discussionmentioning

confidence: 99%

Insulin-like growth factor and growth hormone receptor in postpartum lactating beef cows

Schneider

Pfeifer²,

Hax³

et al. 2010

Pesq. agropec. bras.

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“…Pre-partum IGF-I concentrations tended to be greater in MH cows than in ML cows, which was consistent with the better BCS of these animals. Concentrations of IGF-I decreased at calving, as reported previously (Lucy et al, 2001;Taylor et al, 2003;Meikle et al, 2004). It is interesting to note that IGF-I profiles reflected more likely the changes in BCS, in contrast with insulin profiles, which were associated more with the day-to-day effects of the nutritional input as observed in the pre-partum increases in low BCS cows.…”

Section: Discussionsupporting

confidence: 79%

“…A decrease in insulin at calving was observed in all groups, which is a metabolic adaptation to cope with the energy demands of lactation, as reported earlier (Taylor et al, 2003;Wathes et al, 2007), as low insulin levels favor gluconeogenesis and lipolysis (Herdt, 2000; e.g. homeorhetical effect).…”

Section: Discussionsupporting

confidence: 72%

Nutritional regulation of body condition score at the initiation of the transition period in primiparous and multiparous dairy cows under grazing conditions: milk production, resumption of post-partum ovarian cyclicity and metabolic parameters

Adrien

Mattiauda

Artegoitia

et al. 2012

Animal

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The objective of this study was to investigate the effect of different body condition score (BCS) at 30 days before calving (230 days) induced by a differential nutritional management from 2100 days until 230 days on productive parameters, the interval to first ovulation and blood parameters in primiparous and multiparous Holstein cows under grazing conditions until 60 days post partum. The experimental arrangement was a randomized complete block design, where cows were blocked according to BW and expected calving date and then randomly assigned to different nutritional treatments from -100 to -30 days relative to calving to induce different BCS. As the assignment of cows to treatments was random, cows had to lose, maintain or gain BCS; thus, different planes of nutrition were offered with approximately 7, 14 or 20 kg dry matter per day. The BCS score was assessed every 15 days and animals were reassigned in order to achieve the desired BCS at -30 days. Only animals that responded to nutritional treatment were considered and this was defined as follows: primiparous and multiparous high cows (PH and MH) had to gain 0.5 points of BCS, primiparous low (PL) had to lose 0.5 points of BCS and multiparous low (ML) had to maintain BCS at least in two subsequent observations from 2100 to 230 days. From 230 days to calving, primiparous and multiparous cows (P and M cows) were managed separately and cows were offered a diet once a day. From calving to 60 days post partum, cows of different groups grazed in separate plots a second year pasture. Cows were also supplemented individually with whole-plant maize silage and commercial concentrate. Cows had similar BCS at 2100 days and differed after the nutritional treatment; however, all groups presented similar BCS at 21 days post partum. The daily milk production and milk yield at 60 days post partum was higher in M than P cows. The percentage of milk fat was higher in PH cows compared with PL cows. Concentrations of non-esterified fatty acids (NEFA) were affected by the BCS at 230 days within parity, and in PH cows the concentration of NEFA was higher than in PL cows. The concentrations of total protein were higher in M cows. A lower probability of cycling was found in PL than in PH cows (P , 0.05) and in ML than in MH cows (P , 0.05). Treatment affected various endocrine/metabolic profiles according to parity, suggesting that the metabolic reserves signal the productive/reproductive axis so as to induce a differential nutrient partitioning in adult v. first-calving cows.

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“…the younger animals. Since it has been suggested that low insulin and IGF-I are the metabolic signals that delay ovulation (Beam & Butler 1999) and IGF-I concentrations were high in primiparous cows, Taylor et al (2003) suggested that in this category -which is still growing -insulin concentrations may be limiting, whereas in older cows a closer association is observed between IGF-I and fertility parameters. Our results do not support this hypothesis since primiparous cows presented lower IGF-I but similar insulin concentrations and presented a delayed ovulation when compared with multiparous cows.…”

Section: Discussionmentioning

confidence: 99%

Effects of parity and body condition at parturition on endocrine and reproductive parameters of the cow

Meikle¹,

Kulcsár²,

Chilliard³

et al. 2004

Reproduction

201

159

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The effect of parity (multiparous vs primiparous) and body condition score (BCS; <3.0 or $ 3.0, lean vs fat) at parturition on metabolic and endocrine profiles from 1 month before to 2 months after parturition were studied in 42 Holstein cows grazing on improved pastures. BCS and milk production were determined every 2 weeks. Non-esterified fatty acids (NEFA), b-hydroxybutyrate (BHB), insulin, IGF-I, leptin, thyroxine (T4) and 3,3 0 ,5-tri-iodothyroinine (T3) were determined in plasma every 10 days. Progesterone was determined three times per week after parturition. Primiparous cows had a lower BCS during the early postpartum period and produced less milk than multiparous animals. Primiparous cows had higher NEFA concentrations and they presented more samples with BHB concentrations of >1 mmol/l than multiparous cows. Multiparous cows had higher T3, T4 and IGF-I concentrations, while fat cows had higher leptin and IGF-I concentrations. All hormone concentrations were diminished in the first week postpartum. Primiparous cows and fat cows presented a steeper decay of IGF-I and leptin around parturition than multiparous cows and lean cows. While thyroid hormones and IGF-I showed increasing concentrations from approximately day 30, leptin concentrations remained low until the end of the experimental period. The initiation of ovarian cyclicity was delayed in primiparous cows and especially in primiparous lean cows, consistent with longer intervals from parturition to first service and to conception. The endocrine signals most likely to inform the reproductive axis regarding a negative energy balance were IGF-I and leptin.

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Metabolic profiles and progesterone cycles in first lactation dairy cows

Cited by 86 publications

References 28 publications

Insulin-like growth factor and growth hormone receptor in postpartum lactating beef cows

Insulin-like growth factor and growth hormone receptor in postpartum lactating beef cows

Nutritional regulation of body condition score at the initiation of the transition period in primiparous and multiparous dairy cows under grazing conditions: milk production, resumption of post-partum ovarian cyclicity and metabolic parameters

Effects of parity and body condition at parturition on endocrine and reproductive parameters of the cow

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