Metabolic Disorders in Dairy Calves in Postpartum Period

Podhorský, A.; Pechová, Alena; Dvořák, R.; Pavlata, L.

doi:10.2754/avb200776s8s045

Cited by 15 publications

(13 citation statements)

References 7 publications

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“…anaemia presented a significant reduction in serum IGF-I compared to calves with optimal iron concentration on day 10. The results obtained in our study are similar to other studies that investigated metabolic and endocrine changes during iron deficiency in veal calves (Ceppi and Blum 1994;Blum and Hammon 1999;Podhorský et al 2007). The IGF-I status markedly depends on energy and protein intake, as also shown in calves (Hammon and Blum 1998;Blum and Baumrucker 2002).…”

Section: Indicatorssupporting

confidence: 91%

Relationship between serum iron and insulin-like growth factor-I concentrations in 10-day-old calves

et al. 2014

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Newborn calves are often deficient in iron and progressive reduction in blood iron concentration occurs over the first weeks of life. Some reports indicate the importance of interactions among iron and components of the insulin-like growth factor system. The aim of the study was to determine if there is a relationship between serum iron and insulin-like growth factor-I concentrations in neonatal calves. Blood samples were collected from 16 female Holstein-Friesian calves on day 10 of age. Erythrogram determination and measurements of serum iron, total protein, albumin, total iron binding capacity and serum insulin-like growth factor-I concentrations were performed. Haematological values were measured using an automatic analyzer, biochemical properties were determined spectrophotometrically, insulin-like growth factor-I concentration was measured by radioimmunoassay. Calves were divided into 2 groups according to iron concentrations; the first group of iron-deficient calves (n = 8, Fe < 10 μmol/l) and the second group of calves with optimal iron concentration (n = 8, Fe > 18 μmol/l). Blood indicators in all calves from the first group followed a pattern typically observed in anaemic calves. Insulin-like growth factor-I concentrations were significantly (P < 0.01) lower in the first group compared to the second group. However, insulin-like growth factor-I very strongly correlated with iron in calves from the second group compared to iron-deficient calves (r = 0.624; P < 0.01 and r = 0.478; P > 0.05, respectively). Based on our results, iron seems to have an important relationship to secretion of insulin-like growth factor-I in 10-day-old calves. This is the first report about such relationship in this age group of animals. Calf, haematology, IGF-I, iron deficiency

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Section: Indicatorssupporting

confidence: 91%

Relationship between serum iron and insulin-like growth factor-I concentrations in 10-day-old calves

et al. 2014

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“…We consider as interesting finding that GGT activity is lower in the group of crias than in older alpacas even when evaluating the crias < 2 weeks old. Our expectation for few days old crias would be high activity of GGT due to effect of colostrum consumption similarly as in young calves (Podhorsky et al, 2007). All crias included in our study were clinically healthy with no signs of inadequate colostrum intake; while most data published for GGT activity in few days old crias are describing animals tested and treated for failure of passive transfer of immunity.…”

Section: Discussionmentioning

confidence: 81%

Reference values for biochemical parameters in blood serum of young and adult alpacas (Vicugna pacos)

Husáková

Pavlata

Pechová

et al. 2014

Animal

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The aim of this study was to establish reference interval for biochemical parameters in blood of alpacas on the basis of large population of clinically healthy animals, and to determine the influence of sex, age and season on nitrogen and lipid metabolites, enzymes, electrolytes, vitamins and minerals in blood of alpacas. Blood samples were collected from 311 alpacas (61 males and 201 females > 6 months of age and 49 crias (21 males and 28 females) ⩽ 6 months of age). Selected farms were located in Central Europe (Czech Republic and Germany). We determined 24 biochemical parameters from blood serum. We performed the comparison of results by the sex of animals and for the older group also the comparison of the results with regard to the season, respectively, to the feeding period. We found no highly significant difference (P < 0.01) between males and females with the exception of γ-glutamyl transferase (GGT), alkaline phosphatase (ALP) and cholesterol. We found 15 significantly different parameters between the group of crias 6 months of age and the older alpacas. Based on our findings we suggest for most parameters to use different reference intervals (especially ALP, cholesterol, total protein, globulin, non-esterified fatty acids (NEFA), GGT and phosphorus) for the two above-mentioned age groups. Another important finding is the differences between some parameters in older group of alpacas in summer/winter feeding period. Animals in the summer feeding period have higher values of parameters related to fat mobilization (β-hydroxybutyrate, NEFA) and liver metabolism (bilirubin, alanine aminotransferase). The winter period with increased feeding of supplements with higher amount of fat, vitamins and minerals is characteristic by increased values of cholesterol, triglycerides, vitamins A and E, and some minerals (K, Ca, Mg and Cl) in blood serum. Clinical laboratory diagnosis of metabolic disturbances may be improved with use of age-based reference values and with consideration of seasonal differences.Keywords: alpaca, llama, reference ranges, clinical pathology, seasonal differences ImplicationsOne of the important methods of monitoring health status is evaluation of blood. To interpret results correctly we need to consider species-specific differences, and influence of other factors: gender, age, nutrition, season and environment. South American camelids -especially alpacas -are growing in popularity all over Europe and yet there is lack of knowledge of above-mentioned factors on their blood parameters. This study evaluated influence of these factors on blood parameters of alpacas. The result should help veterinarians and alpaca breeders with correct interpretation of blood tests to diagnose clinical and subclinical metabolic health problem and possible nutritional disturbances.

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“…It has been described in cattle (Pavlata et al, 2002(Pavlata et al, , 2005aPodhorsky et al, 2007) and horses (Ludvikova et al, 2005), but information concerning selenium supplementation in small ruminants is scarce.…”

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confidence: 99%

Selenium metabolism in goats - maternal transfer of selenium to newborn kids

Mišurová¹,

Pavlata²,

Pechová³

et al. 2009

Vet. Med.

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AbStrAct:The aim of our study was to compare the concentration of selenium (Se) and the activity of glutathione peroxidase (GSH-Px) in the whole blood of goats and their newborn kids. The experiment involved 25 gravid, clinically healthy goats of the white shorthaired breed. On the day of delivery, we took whole blood from the mother and her newborn kid before the kid drank the first colostrum. In mothers, the measured average concentration of Se in whole blood was 149.60 ± 45.01 μg/l, the average concentration of Se in kids was 87.91 ± 29.66 μg/l. Average activity of GSH-Px in the blood of mothers was 938.46 ± 341.09 μkat/l, and in the blood of kids 658.20 ± 339.13 μkat/l. Regression and correlation analysis produced regression line formulas and correlation coefficients that revealed a close, statistically significant relation (p < 0.01) between the concentration of Se in the blood of mothers and their kids and the activity of GSH-Px in mothers and their kids. The relation between the concentration of Se in the blood (µg/l) of mothers and kids was y = 0.484x + 15.55; r = 0.73, the relation between the activity of GSH-Px in blood (µkat/l) of mothers and their kids was y = 0.809x -101.27; r = 0.80. The concentration of Se and activity of GSH-Px was lower in newborn kids than in their mothers, reaching approximately 60-70% of the mother's levels. The relation between the concentration of Se and activity of GSH-Px in the blood of goats was y = 4.23x + 276.31; r = 0.64 (p < 0.01) and the relation between the concentration of Se and the activity of GSH-Px in the blood of kids was y = 6.556x + 64.70; r = 0.83 (p < 0.01). It follows that a Se concentration of 100 μg/l corresponds to a GSH-Px activity of 699.51 μkat/l in the blood of mothers and 720.34 μkat/l in the blood of kids. The results show the need to provide for a sufficient Se saturation of goats with a view to preventing Se deficiency in kids and that the Se concentration in the blood of newborn kids is physiologically about 40% lower in comparison with the Se concentration in the blood of their mothers. This should be taken into account when interpreting the results and assessing the reference values of Se concentration in the blood of kids.

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Metabolic Disorders in Dairy Calves in Postpartum Period

Cited by 15 publications

References 7 publications

Relationship between serum iron and insulin-like growth factor-I concentrations in 10-day-old calves

Relationship between serum iron and insulin-like growth factor-I concentrations in 10-day-old calves

Reference values for biochemical parameters in blood serum of young and adult alpacas (Vicugna pacos)

Selenium metabolism in goats - maternal transfer of selenium to newborn kids

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