Metabolic activation of meta-phenylenediamine by the alga Chlamydomonas reinhardtii

m-Phenylenediamine and m-Phenylenediamine Sulfate

“…The Expert Panel reviewed newly available studies since that assessment along with updated frequency and concentration of use information. 2 –29 The Expert Panel determined to not reopen this safety assessment and confirmed the original conclusion of m-phenylenediamine and m-phenylenediamine sulfate.…”

Green Algae Can Modulate the Genotoxic Action of Cadmium in Human Lymphocytes

“…it is known that different low molecular metabolites, organic acids, free amino acids, enzymes are released in the culture medium as a result of the natural metabolic activity of unicellular green algae (9,31). on the other hand other mechanisms should also not be excluded because plants have a range of potential mechanisms at the cellular level that might be involved in the detoxification of heavy metals.…”

“…the use of immobilized unicellular algae and other microorganisms in metals preconcentration and remediation has a long history with encouraging results (22). on the other hand algae can store and metabolize promutagens to mutagenic products that may be introduced into the human food chain (28,31), as well as release activated metabolized products in extracted media (32). one of the main open questions is whether unicellular green algae and metabolized products released in the environment can modulate the potential genotoxic effect of some xenobiotics.…”