Metabolic activation of three arylamines and two organophosphorus insecticides by coriander (Coriandrum sativum) a common edible vegetable

Cortés-Eslava, Josefina; Gómez‐Arroyo, Sandra; Villalobos‐Pietrini, Rafael; Espinosa-Aguirre, J.J.

doi:10.1016/s0378-4274(01)00414-3

Cited by 8 publications

(1 citation statement)

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“…Fourteen of the extracts, including the Pc extract, inhibited the promotion phase by at least 70% (Koshimizu, 1991). In addition, the acetone extract of Cs exhibited inhibitory effects on mutagenicity (Cortés-Eslava et al, 2001). Both Pc and Cs are umbelliferous plants, and their edible portions contain functional components with antioxidant or anti-mutagenic properties, such as a variety of vitamins and flavonoids.…”

Section: Inhibitory Effects Of Pc and Cs On Micronucleus Inductionmentioning

confidence: 99%

Effects of Petroselinum crispum and Coriandrum sativum on Oral Cadmium-induced Micronucleus Formation in Mice

Ren

Jia

Suzuki

et al. 2013

FSTR

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This paper reports the effects of umbelliferous plants on Cd-induced micronucleus formation in Cdexposed mice. After ICR mice (7 w) were given free access to a 100 mg/kg Cd solution for 12 days, they were fed with a standard diet and a control diet supplemented with Petroselinum crispum (Pc) or Coriandrum sativum (Cs) for 70 days. Femoral bone marrow smears were prepared every 2 weeks, and micronucleus frequency was determined from the micronucleated polychromatic erythrocyte count. The micronucleus frequency obtained from the positive control group was approximately 2-fold higher than that in the negative control group (No Cd administration) (P < 0.05). However, micronucleus frequencies in the Cs and Pc groups were decreased by 21 − 60% (P < 0.05) compared to that of the positive control group. These results suggest that consumption of these two plants might inhibit genotoxicity and possibly even reduce the risk of aging and carcinogenesis induced by Cd.

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Section: Inhibitory Effects Of Pc and Cs On Micronucleus Inductionmentioning

confidence: 99%