Abstract:Infants who have suffered neonatal sepsis face an increased risk of mortality and severe complications such as brain damage and, or, neurodevelopmental delay.
“…Despite recent advances in neonatal intensive care, sepsis remains an important cause of morbidity and mortality, particularly among preterm infants [1,2] . Neonatal sepsis causes poor neurodevelopmental outcomes in preterm infants [3][4][5][6][7] .…”
Section: Resultsmentioning
confidence: 99%
“…Neonatal sepsis is a major cause of morbidity and mortality in neonatal intensive care units [1] and is prevalent in premature infants [2] . Many clinical studies have…”
“…Despite recent advances in neonatal intensive care, sepsis remains an important cause of morbidity and mortality, particularly among preterm infants [1,2] . Neonatal sepsis causes poor neurodevelopmental outcomes in preterm infants [3][4][5][6][7] .…”
Section: Resultsmentioning
confidence: 99%
“…Neonatal sepsis is a major cause of morbidity and mortality in neonatal intensive care units [1] and is prevalent in premature infants [2] . Many clinical studies have…”
“…Infants who have had culture-proven late-onset neonatal bloodstream infections have higher mortality than those who have not had these infections [1,6]. Late-onset neonatal bloodstream infections in very low birth weight infants bestow independent risks to long-term child development, in addition to the wellrecognized risks bestowed by brain injury, bronchopulmonary dysplasia, and retinopathy of prematurity [2].…”
“…Infants who have suffered neonatal sepsis face an increased risk for brain damage and neurodevelopmental delays [2,3], whereas, experimental data have shown that inflammation/infection early in life may alter the developmental trajectory of the immune system and the brain [4,5]. Early diagnosis and management of neonatal infection improves prognosis; thus, the identification of new or complementary biomarkers of neonatal infection or sepsis is of potential importance [6].…”
Circulating ghrelin, but not PYY(3-36), levels are increased in neonates with infection, possibly reflecting and/or participating in the inflammatory process.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.