“…This, in addition to reduced operative time, may compensate for the higher cost of the LigaSure electrodes, particularly since reduced pain did not lead to a shorter hospital stay. Tan et al [20], in their meta-analysis study, reported that the cost of each single-use Ligasure device is about $156 and that by making possible shortened operative times, decreased blood loss, and reduced postoperative pain, LigaSure may produce a cost benefit, though this assessment was not performed in any of the studies analyzed. A further study is obviously and admittedly needed to verify cost-effectiveness of LH versus OH.…”