Message in a Bottle: Dialog between Intestine and Skin Modulated by Probiotics

Abstract

At the beginning, probiotics were used exclusively for gastrointestinal conditions. However, over the years, evidence has shown that probiotics exert systemic effects. In this review article, we will summarize recent reports that postulate probiotic treatment as an efficient one against skin pathologies, such as cancer, allergy, photoaging and skin infections. The focus will be restricted to oral probiotics that could potentially counteract the ultraviolet irradiation-induced skin alterations. Moreover, the possible underlying mechanisms by which probiotics can impact on the gut and exert their skin effects will be reviewed. Furthermore, how the local and systemic immune system is involved in the intestine-cutaneous crosstalk will be analyzed. In conclusion, this article will be divided into three core ideas: (a) probiotics regulate gut homeostasis; (b) gut and skin homeostasis are connected; (c) probiotics are a potentially effective treatment against skin conditions.

The gut microbiome alterations in allergic and inflammatory skin diseases – an update

“…GALT is one of the major immunological structures in our body. It is built up of epithelial layer, Peyer's patches, lamina propria (containing macrophages, dendritic cells, T‐ and B‐lymphocytes alongside with immunoglobulins especially sIgA) and mesenteric lymph nodes . The macromolecules and microorganisms captured in Peyer's patches are presented via dendritic cells to T and B cells provoking the production of plasma cells precursors.…”

Nutraceuticals and skin appearance: Is there any evidence to support this growing trend?

“…Millions of bacteria also reside in the human skin and affect the homoeostasis of the skin immune system (Friedrich et al . ). Furthermore, dysbiosis of the skin microbiota is associated with chronic skin conditions (Friedrich et al .…”

“…Furthermore, dysbiosis of the skin microbiota is associated with chronic skin conditions (Friedrich et al . ). Probiotics are defined as ‘live microorganisms which when administered in adequate amounts confer a health benefit on the host’ (FAO/WHO ).…”

“…Emerging evidence suggests that probiotics may have positive effects on the skin, including protecting against UV‐induced skin damage (Friedrich et al . ) and improving atopic dermatitis (Iemoli et al . ; Foolad et al .…”

Микробиота Кожи И Возможности Ее Коррекции Пре- И Пробиотиками При Лечении Хронических Дерматозов

“…Синдром избыточно-го бактериального роста (СИБР) чаще встре-чается у пациентов с розацеа, чем у здоровых лиц. Лечение и устранение СИБР у пациентов с розацеа уменьшают клинические проявления [36,59]. Воспалительные заболевания кишеч-ника часто имеют проявления на коже [36,60].…”