Mesoporous Silica Nanoparticles in Chemical Detection: From Small Species to Large Bio-Molecules

Parra, Margarita; Gil, Salvador; Gaviña, Pablo; Costero, Ana M.

doi:10.3390/s22010261

Cited by 25 publications

(14 citation statements)

References 86 publications

(81 reference statements)

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“…Silicon‐based NPs used for biomedical applications can be categorized into mesoporous and nonporous solid NPs. Owing to the ease of large‐scale synthesis and low cost, fluorescent silicon‐based NPs doped with fluorescent dyes, QDs and lanthanide‐doped NPs have been extensively studied for detecting various pathogens [49] . Moreover, they are easily surface functionalized by bioconjugation with antigens, antibodies, or enzymes via physical adsorption or silane chemistry [50] .…”

Section: Types and Properties Of Photoluminescent Inorganic Nanomater...mentioning

confidence: 99%

“…Owing to the ease of large-scale synthesis and low cost, fluorescent silicon-based NPs doped with fluorescent dyes, QDs and lanthanide-doped NPs have been extensively studied for detecting various pathogens. [49] Moreover, they are easily surface functionalized by bioconjugation with antigens, antibodies, or enzymes via physical adsorption or silane chemistry. [50] Zhao et al synthesized dye-doped SiO 2 NPs, which were modified with biorecognition molecules for in situ pathogen quantification.…”

Section: Silicon-based Npsmentioning

confidence: 99%

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Photoluminescent Inorganic Nanoprobe‐based Pathogen Detection

Huang

Wang

Xie

2022

Chemistry An Asian Journal

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Pathogens are serious threats to human health, and traditional detection techniques suffer from various limitations. The unique optical properties of photoluminescent inorganic nanomaterials, such as high photoluminescence quantum yields, good photostability, and tunable spectra, make them ideal tools for the detection of pathogens with high specificity and sensitivity. In this review, the design strategies, working mechanisms, and applications of photoluminescent inorganic nanomaterial-based probes in pathogen detection are introduced. In particular, the design and construction of stimuli-responsive nanoprobes and their potential in these fields are highlighted.

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Section: Types and Properties Of Photoluminescent Inorganic Nanomater...mentioning

confidence: 99%

Section: Silicon-based Npsmentioning

confidence: 99%

Photoluminescent Inorganic Nanoprobe‐based Pathogen Detection

Huang

Wang

Xie

2022

Chemistry An Asian Journal

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“…Nevertheless, spiky SiO 2 NPs have been shown to perform as excellent platforms not only for virus-like NPs to investigate adaptive immune responses through the uptake of biological hosts [28][29][30] but also for controlled drug delivery systems with high porosity, chemical stability, and good biocompatibility. [31] To develop and adapt to various practical applications in harsh and complex environments, investigations on the design of spiky SiO 2 NP-based superhydrophobic materials is still necessary and remains challenging. Along with the development of superhydrophobic materials, different coating techniques have been successfully utilized to prepare superhydrophobic surfaces including laser processing, [32] sol-gel, [24] spin coating, [33] deposition, [34,35] dip coating, [16,36] electrolyte jet machining, [37] and spray coatings.…”

Section: Introductionmentioning

confidence: 99%

Transparent Oil–Water Separating Spiky SiO₂ Nanoparticle Supramolecular Polymer Superhydrophobic Coatings

Nguyen

Tran

et al. 2023

Small Methods

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superhydrophobic coatings enabled by the nanocomposite materials of graphene, [5,6] polydimethylsiloxane (PDMS) and TiO 2 , [7] fluoropolysiloxane and TiO 2 , [8] Fe 3 O 4 nanoparticles (NPs), [9] nanocellulose, [10] melanin NPs, [11] cellulose-based derivatives, [12] stoichiometric silanization, [13] fluorinated nanodiamonds, [14] carbon microflowers with MoO 3 NPs, [15] polytetrafluoroethylene, [6] composite microspheres of polystyrene and SiO 2 , [16] SiO 2 and epoxy resin, [17] and fluorinated SiO 2 NPs, [18] SiO 2 NPs embedded with electro-spun fibrous mats, [19] and so on. Mesoporous SiO 2 NPs is one of the most widely studied nanostructures. Researchers have mainly focused on the design of SiO 2 NP-based superhydrophobic nanocomposite materials with various properties including fluorine-free, self-cleaning, environmentfriendly, and antifogging characteristics. [20] For example, superhydrophobic surfaces have been successfully prepared by onestep spray or spin-coating using SiO 2 NPs combined with various supramolecules, including silicone-acrylic copolymer, [3] poly(methyl hydrogen)siloxane, [21] PDMS, [22] organic silicon glass resin prepolymer, [23] 1H,1H,2H,2H-perfluorooctyltriethoxysilane, [24] polystyrene, [16,25] polymethylmethacrylate, and hexadecyl trimethoxy silane. [26] The superhydrophobic efficiency of composite materials depends on the improved performance of A potential application of spiky SiO 2 nanoparticles (NPs) with tubular and rough surfaces is investigated as superhydrophobic coatings, for their unique transparent, fluorinate-free, and environmentally friendly properties. This study demonstrates a facile method for the successful fabrication of superhydrophobic coatings and SiO 2 @polydimethylsiloxane (PDMS) using spiky SiO 2 NPs, N-coordinated boroxines, and PDMS. Combined with spray coating technology, this method of superhydrophobic coating can be simply applied to both hydrophilic and hydrophobic surfaces, including wood, fabric, glass, metal, sponge, and paper. The nanocomposite coating on the glass surface showed both excellent superhydrophobicity and high transparency, with a contact angle of 165.4 ± 1.0° and 96.93% transmittance at 550 nm, respectively. SiO 2 @PDMS-modified glass substrate is found to be resilient to UV irradiation, water, and high temperature treatments at ambient conditions. Experimental data demonstrated that the simple but effective combination of N-boroxine-PDMS and spiky SiO 2 NPs produces a layered coating material that exhibits many good integrated surface properties, including stability, transparency, superhydrophobicity, and oil-water separation.

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“…Shaping the morphology of mesoporous silicate materials into nanosizes led to the development of mesoporous silica nanoparticles (MSN) with broad applications such as catalysis, adsorption, ion exchange, and sensing. [ 2–5 ] In 2001, Pérez‐Pariente et al. discovered the interesting property of MSN as a drug delivery system.…”

Section: Introductionmentioning

confidence: 99%

Mesoporous silica/organosilica nanoparticles for cancer immunotherapy

Theivendran

Lazarev

2023

Exploration

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Cancer is one of the fatal diseases in the history of humankind. In this regard, cancer immunotherapeutic strategies have revolutionized the traditional mode of cancer treatment. Silica based nano-platforms have been extensively applied in nanomedicine including cancer immunotherapy. Mesoporous silica nanoparticles (MSN) and mesoporous organosilica nanoparticles (MON) are attractive candidates due to the ease in controlling the structural parameters as needed for the targeted immunotherapeutic applications. Especially, the MON provide an additional advantage of controlling the composition and modulating the biological functions to actively synergize with other immunotherapeutic strategies. In this review, the applications of MSN, MON, and metal-doped MSN/MON in the field of cancer immunotherapy and tumor microenvironment regulation are comprehensively summarized by highlighting the structural and compositional attributes of the silica-based nanoplatforms.

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Mesoporous Silica Nanoparticles in Chemical Detection: From Small Species to Large Bio-Molecules

Cited by 25 publications

References 86 publications

Photoluminescent Inorganic Nanoprobe‐based Pathogen Detection

Photoluminescent Inorganic Nanoprobe‐based Pathogen Detection

Transparent Oil–Water Separating Spiky SiO₂ Nanoparticle Supramolecular Polymer Superhydrophobic Coatings

Mesoporous silica/organosilica nanoparticles for cancer immunotherapy

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Mesoporous Silica Nanoparticles in Chemical Detection: From Small Species to Large Bio-Molecules

Cited by 25 publications

References 86 publications

Photoluminescent Inorganic Nanoprobe‐based Pathogen Detection

Photoluminescent Inorganic Nanoprobe‐based Pathogen Detection

Transparent Oil–Water Separating Spiky SiO2 Nanoparticle Supramolecular Polymer Superhydrophobic Coatings

Mesoporous silica/organosilica nanoparticles for cancer immunotherapy

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Product

Resources

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Transparent Oil–Water Separating Spiky SiO₂ Nanoparticle Supramolecular Polymer Superhydrophobic Coatings