Mesh Selection in Abdominal Wall Reconstruction

Ellis, Ryan C.; Miller, Benjamin

doi:10.1016/j.suc.2023.04.010

Cited by 6 publications

(6 citation statements)

References 30 publications

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“…Polypropylene (PP) mesh, which is a type of non-absorbable mesh patch, exhibits limited tissue biocompatibility and has the potential to induce significant tissue inflammation. This can result in the formation of abdominal adhesions and friction with the nearby intestine, ultimately leading to the development of intestinal fistulas [ 51 ]. Moreover, these materials do not possess inherent regeneration qualities.…”

Section: Abdominal Wall Anatomy and Available Treatmentsmentioning

confidence: 99%

Recent Advances in Functional Hydrogel for Repair of Abdominal Wall Defects: A Review

Liu,

Huang,

et al. 2024

Biomater Res

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The abdominal wall plays a crucial role in safeguarding the internal organs of the body, serving as an essential protective barrier. Defects in the abdominal wall are common due to surgery, infection, or trauma. Complex defects have limited self-healing capacity and require external intervention. Traditional treatments have drawbacks, and biomaterials have not fully achieved the desired outcomes. Hydrogel has emerged as a promising strategy that is extensively studied and applied in promoting tissue regeneration by filling or repairing damaged tissue due to its unique properties. This review summarizes the five prominent properties and advances in using hydrogels to enhance the healing and repair of abdominal wall defects: (a) good biocompatibility with host tissues that reduces adverse reactions and immune responses while supporting cell adhesion migration proliferation; (b) tunable mechanical properties matching those of the abdominal wall that adapt to normal movement deformations while reducing tissue stress, thereby influencing regulating cell behavior tissue regeneration; (c) drug carriers continuously delivering drugs and bioactive molecules to sites optimizing healing processes enhancing tissue regeneration; (d) promotion of cell interactions by simulating hydrated extracellular matrix environments, providing physical support, space, and cues for cell migration, adhesion, and proliferation; (e) easy manipulation and application in surgical procedures, allowing precise placement and close adhesion to the defective abdominal wall, providing mechanical support. Additionally, the advances of hydrogels for repairing defects in the abdominal wall are also mentioned. Finally, an overview is provided on the current obstacles and constraints faced by hydrogels, along with potential prospects in the repair of abdominal wall defects.

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Section: Abdominal Wall Anatomy and Available Treatmentsmentioning

confidence: 99%

Recent Advances in Functional Hydrogel for Repair of Abdominal Wall Defects: A Review

Liu,

Huang,

et al. 2024

Biomater Res

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“…Hernia repair is favored by interdisciplinary technological advances, as its performant management benefits from developments in bioprosthetic devices, materials, surgical techniques, and combined approaches [24]. Concerning mesh options, a wide range of biomedical textiles are clinically available, each with advantages and disadvantages depending on placement position and usage circumstances [9]. In the following subsections, currently available meshes are briefly presented depending on their manufacturing materials, being divided into synthetic, biological, and composite meshes.…”

Section: Currently Available Abdominal Meshesmentioning

confidence: 99%

“…Still, surgical meshes are the preferential choice for restoring the physical integrity and equivalent components of musculofascial layers [1,8]. Nowadays, clinicians can choose from a variety of meshes, each with its own benefits and limitations [9]. However, an optimally performing such medical textile is yet to be found [10], and increasing research interest has been noted in improving polymer architecture, biocompatibility, operative handling, and cost of these reinforcement structures [8].…”

Section: Introductionmentioning

confidence: 99%

A Review of Abdominal Meshes for Hernia Repair—Current Status and Emerging Solutions

Najm,

Niculescu,

Gaspar

et al. 2023

Materials

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Abdominal hernias are common issues in the clinical setting, burdening millions of patients worldwide. Associated with pain, decreased quality of life, and severe potential complications, abdominal wall hernias should be treated as soon as possible. Whether an open repair or laparoscopic surgical approach is tackled, mesh reinforcement is generally required to ensure a durable hernia repair. Over the years, numerous mesh products have been made available on the market and in clinical settings, yet each of the currently used meshes presents certain limitations that reflect on treatment outcomes. Thus, mesh development is still ongoing, and emerging solutions have reached various testing stages. In this regard, this paper aims to establish an up-to-date framework on abdominal meshes, briefly overviewing currently available solutions for hernia repair and discussing in detail the most recent advances in the field. Particularly, there are presented the developments in lightweight materials, meshes with improved attachment, antimicrobial fabrics, composite and hybrid textiles, and performant mesh designs, followed by a systematic review of recently completed clinical trials.

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“…[ 5,6 ] However, the optimal selection of abdominal wall hernia patch materials (AWHPMs) is crucial in attaining a low recurrence rate in abdominal wall repair (AWR) surgery ( Figure A). [ 7 ]…”

Section: Introductionmentioning

confidence: 99%

A Review of Advanced Abdominal Wall Hernia Patch Materials

Liang,

Ding,

et al. 2023

Adv Healthcare Materials

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Tension‐free abdominal wall hernia patch materials (AWHPMs) play an important role in the repair of abdominal wall defects (AWDs), which have a recurrence rate of <1%. Nevertheless, there are still significant challenges in the development of tailored, biomimetic, and extracellular matrix (ECM)‐like AWHPMs that satisfy the clinical demands of abdominal wall repair (AWR) while effectively handling post‐operative complications associated with abdominal hernias, such as intra‐abdominal visceral adhesion and abnormal healing. This extensive review presents a comprehensive guide to the high‐end fabrication and the precise selection of these advanced AWHPMs. The review begins by briefly introducing the structures, sources, and properties of AWHPMs, and critically evaluates the advantages and disadvantages of different types of AWHPMs for AWR applications. The review subsequently summarizes and elaborates upon state‐of‐the‐art AWHPM fabrication methods and their key characteristics (e.g., mechanical, physicochemical, and biological properties in vitro/vivo). This review uses compelling examples to demonstrate that advanced AWHPMs with multiple functionalities (e.g., anti‐deformation, anti‐inflammation, anti‐adhesion, pro‐healing properties, etc.) can meet the fundamental clinical demands required to successfully repair AWDs. In particular, there have been several developments in the enhancement of biomimetic AWHPMs with multiple properties, and additional breakthroughs are expected in the near future.

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Mesh Selection in Abdominal Wall Reconstruction

Cited by 6 publications

References 30 publications

Recent Advances in Functional Hydrogel for Repair of Abdominal Wall Defects: A Review

Recent Advances in Functional Hydrogel for Repair of Abdominal Wall Defects: A Review

A Review of Abdominal Meshes for Hernia Repair—Current Status and Emerging Solutions

A Review of Advanced Abdominal Wall Hernia Patch Materials

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