Mesenteric vascular occlusion complicating thrombo-angiitis obliterans

Garvin, Eugene J.

doi:10.1016/0002-9610(47)90166-9

Cited by 10 publications

(1 citation statement)

References 11 publications

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“… perigastric nodes were enlarged up to 4 by 2 cm Histology demonstrated no malignancy but perivascular inflammation without thrombotic occlusion. The involved portion of the stomach was resected Recovery 32 1947 Garvin (Pennsylvania, USA) 34 1 33 years Abdominal pain, distention and vomiting History of same presentation 8 years earlier TAO diagnosis 8 months earlier Unknown Laparotomy by diagnosis of mesenteric ischemia The histology was supportive for TAO diagnosis Resection 45 cm of gangrenous proximal ilium Unknown …”

Section: Gastrointestinal Tractmentioning

confidence: 99%

<p>Visceral bed involvement in thromboangiitis obliterans: a systematic review</p>

Fakour¹,

Fazeli²

2019

VHRM

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One of the challenges of thromboangiitis obliterans (TAO) management is in the patients whose other vascular beds are involved and it remains a challenge to know whether to pursue invasive procedures or to continue medical treatment for such TAO patients. The aim of this review was to investigate reports of the involvement of the visceral vessels in TAO and the related clinical manifestations, management approaches and outcomes. According to our systematic review, the frequency of published articles, the organs most commonly involved were the gastrointestinal tract, the heart, the central nervous system, the eye, the kidneys, the urogenital system, the mucocutaneous zones, joints, lymphohematopoietic system and the ear. Notably, reports of the involvement of almost all organs have been made in relation to TAO. There were several reports of TAO presentation in other organs before disease diagnosis, in which the involvement of the extremities presented after visceral involvement. The characteristics of the visceral arteries looked like the arteries of the extremities according to angiography or aortography. Also, in autopsies of TAO patients, the vascular involvement of multiple organs has been noted. Moreover, systemic medical treatment could lead to the recovery of the patient from the onset of visceral TAO. This study reveals that TAO may be a systemic disease and patients should be aware of the possible involvement of other organs along with the attendant warning signs. Also, early systemic medical treatment of such patients may lead to better outcomes and reduce the overall mortality rate.

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