Merrillianin, a unique seco-prezizaane-type sesquiterpene, and (6R)-pseudomajucin from Illicium merrillianum

Seven Novel seco-Prezizaane-Type Sesquiterpenes from the Pericarps of Illicium merrillianum

“…Fractions A-E were purified by various types of chromatography to afford new compounds, as described in our previous papers. [7][8][9][10][11][12][13][14] Our further studies of the residual fractions E, D, and C led to the isolation of seven new sesquiterpenes 1-7. This paper deals with the isolation and structural elucidation of these new sesquiterpenes.…”

“…We have continued chemical studies on the pericarps of Illicium merrillianum since 1999. As results, about 36 structurally novel sesquiterpenes have been isolated from this species [7][8][9][10][11][12][13][14] and classified into the seco-prezizaane, anislactone, and allo-cedrane types. It is worthy of note that an anislactone-type compound, merrilactone A, isolated from this plant shows interesting neurotrophic activity.…”

“…The isolation of an equilibrated mixture of 4 and 5 as well as of 6 and 7 adds two other examples to this case. To date, these types of mixture have been found to appear in the pseudoanisatin-, 19) minwanensin-, and pesudomajucin-subtypes 7) of seco-prezizaanetype sesquiterpenes. However, some compounds of these subtypes exist as one form.…”

Merrilliadione – a Rare Isopropyl (13→11)‐abeo‐9,11‐seco Abietane Diterpene from Illicium merrillianum

“…[1] Almost 60 compounds have been isolated from the pericarps of I. merrillianum by Fukuyama and co-workers since 1999, [2][3][4][5][6][7][8][9][10] and the anislactone-type sesquiterpene merrilactone A has received considerable attention owing to its outstanding neurotrophic activity and unique architecture. Its bark, root bark, and fruit have been locally used as folk medicine for the treatment of rheumatism in the southwest of China.…”

Novel Sesquiterpenoid Glycosides and Sesquiterpenes from the Roots of Illicium henryi

“…Species of the genus Illicium L (Illiciaceae) are characterized by a variety of structurally unique sesquiterpenes such as seco-prezizaane-type [1][2][3], anislactone, and allo-cedrane sesquiterpenes [4][5][6], some of which were found to exhibit intriguing neurotrophic activities [7][8][9]. In our previous studies, we investigated the chemical constituents of I. oligandrum [10][11][12], I. simonsii [13], I. difengpi [14], and I. dunnianum [15].…”