Mental nerve neuropathy: A complication of sickle-cell crisis

Friedlander, Arthur H.; Genser, Larry; Swerdloff, M

doi:10.1016/0030-4220(80)90025-0

Cited by 63 publications

(32 citation statements)

References 3 publications

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“…13,14,15,16,17 Permanent neuropathies affecting the inferior dental nerve after an SCA have been reported and resulted in persistant anesthesia for up to 24 months. 18,19 The occurrence of asymptomatic pulp necrosis has been described in clinically intact permanent teeth in patients with SCA. It has been associated to vaso-occlusion of the pulp microcirculation.…”

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confidence: 99%

Sickle cell anemia in Brazil: personal, medical and endodontic patterns

et al. 2016

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Sickle cell anemia (SCA) is the most prevalent genetic disease worldwide. Recurrent vaso-occlusive infarcts predispose SCA patients to infections, which are the primary causes of morbidly and mortality. This study aimed to evaluate the relationship between SCA and endodontic diseases. Personal information, medical data (hematological indices, virologic testing, blood transfusions, medications received, splenectomy) and information on the need for endodontic treatment were obtained from SCA patients who were registered and followed up by the Fundação Hemominas, Minas Gerais, Brazil.These data were compared with the need for root canal treatment in SCA patients. One hundred eight patients comprised the studied population, and the rate of the need for endodontic therapy was 10.2%. Among the medical data, a significant difference was observed for eosinophil (p = 0.045) counts and atypical lymphocyte counts (p = 0.036) when the groups (with and without the need for endodontic treatment) were compared. Statistical relevance was observed when comparing the patients with and without the need for root canal therapy concerned eosinophil counts and atypical lymphocyte counts. The differences in statistical medical data, observed between the groups suggest that both parameters are naturally connected to the stimulation of the immune system that can occur in the presence of root canal infections and that can be harmful to SCA individuals.

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Sickle cell anemia in Brazil: personal, medical and endodontic patterns

et al. 2016

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“…There have been reports of paresthesia of the mental nerve secondary to sickle‐cell anemia crises (Kirson and Tomaro, 1979; Friedlander et al , 1980), benign lymphogranulomatosis (sarcoidosis) (Cohen and Reinhardt, 1982), amyloidosis (Spillane and Wells, 1959; Gastaut and Michel, 1984), diabetic polyradiculoneuropathy (Casamassimo and Tuker, 1988), and multiple scleroses – such paresthesias being the first symptom or manifestation of the disease in 2–3% of patients (Roistacher, 1973; Durward et al , 1990). Likewise, alterations of the mental nerve have been described in located forms of Castelman's disease (Gabrielli et al , 1991), poisoning by trichloroethylene or stilbamidine (Goldstein et al , 1963), and cerebrovascular diseases such as spontaneous bleeding of the protuberance (Berlit, 1989) or ischemic vertebrobasilar damage (Nelson et al , 1986).…”

Section: Trigeminal Neuropathy Variantsmentioning

confidence: 99%

Trigeminal neuropathy

Peñarrocha

Marti³

et al. 2007

Oral Diseases

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Trigeminal neuropathies (TNs) are well recognized disorders characterized and manifesting as skin and mucosal numbness in the region innervated by the trigeminal nerve. Facial numbness indicates trigeminal sensory alteration affecting the trigeminal system. TNs always pose differential location difficulties as multiple diseases are capable of producing them: they can be the result of traumatism, tumors, or diseases of the connective tissue, infectious or demyelinating diseases, or may be of idiopathic origin. Their importance is explained by the fact that TN may represent the first manifestation of tumor disease, or of relapse in patients with prior neoplastic processes. As such, these manifestations are ominous, and patient life expectancy is often short. The clinical exploration reveals a loss of sensitivity in the cutaneous territory corresponding to the affected nerve, which can be partial (hypoesthesia) or complete (anesthesia). The sensory defect is occasionally associated with hyperesthesia (i.e., the patient suffers a decrease in sensory perception, but when sensation is perceived, it may cause considerable discomfort). Complementary studies are needed to establish the etiologic diagnosis, with laboratory tests to discard the possible causative diseases underlying the trigeminal neuropathy, and the opportune radiographic examinations in the form of plain X‐rays or a routine cranial computed tomography scan.

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“…In patients with SCD, infarcts in the jaws may cause pain which may be mistaken for toothache or osteomyelitis [6], and there have also been reports of an increase in dental pain in the apparent absence of specific pathology [7]. Mental nerve paraesthesia [8] and severe mandibular pain [9] have been reported in patients admitted to hospital in acute crisis. Skeletal maturation may be delayed [lo], as children with SCD generally exhibit poor growth and delayed puberty.…”

Section: Dental Manifestations Of Sickle Cell Disorder and (3-thalassmentioning

confidence: 99%

The dental management of children with sickle cell disease and β‐thalassaemia: a review

Duggal

Bedi

Kinsey

et al. 1996

Int J Paed Dentistry

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Summary. This paper reviews two groups of haemoglobinopathies: sickle cell disorders and β‐thalassaemias. The medical aspects and dental management of children with these conditions are discussed. These conditions are rare in the white indigenous population of the UK but affect a sizeable proportion of the minority ethnic community. Dentists need to be aware of the medical implications for patients who have these disorders and should co‐ordinate their dental care accordingly. Resumé. Prise en charge dentaire d'enfants souffrant d'anémie falciforme et d'hypothalasémie béta: revue de la littérature Cette étude passe en revue deux groupes d'hémoglobulinopathie: anémie falciforme et béta thalassémie. Les aspects médicaux et la prise en charge dentaire de ces maladies sont discutés. Ces maladies sont rares dans la population blanche indigène du Royaume‐Uni mais atteignent une proportion notable de la population d'origine ethnique minoritaire. Les dentistes doivent connaître les problèmes médicaux de ces patients et en tenir compte lors des traitements dentaires. Zusammenfassung. Die zahnärztliche Behandlung von Kindern mit der Sikle‐Zellen Erkrankung und mit der Beta‐Thalasemie: eine Uebersicht Diese Arbeit befasst sich mit 2 Gruppen von Hämoglobinopathien. Die medizinische Aspekte und die daraus resultierende zahnärztliche Besonderheiten werden diskutiert. Diese Krankheiten sind selten in der weissen Bevölkerung der U.K. aber befällt einen gewissen Prozensatz der Minderheitsgruppe. Zahnärzte sollten die medizinischen Besonderheiten kennen und dementsprechend die zahnärztliche Betreuung koordinieren. Resumen. Tratamiento dental de niños con enfermedad de células falsiformes y β‐thalasemia Este artículo revisa dos grupos de hemoglobinopatías: trastornos de células falsiformes y β‐thalasemia. Se discuten los aspectos médicos y el tratamiento dental de niños con estas condiciones. Estas condiciones son raras en la población blanca del Reino Unido, peró afecta una gran proporción de la minoría étnica. Los odontólogos deben estar informados sobre las implicaciones médicas de los pacientes que presentan estos trastornos y deben coordinar adecuadamente el tratamiento odontológico.

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Mental nerve neuropathy: A complication of sickle-cell crisis

Cited by 63 publications

References 3 publications

Sickle cell anemia in Brazil: personal, medical and endodontic patterns

Sickle cell anemia in Brazil: personal, medical and endodontic patterns

Trigeminal neuropathy

The dental management of children with sickle cell disease and β‐thalassaemia: a review

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