Meningitis Caused by Flavobacterium meningosepticum. The First Epidemic Outbreak of Meningitis in the Newborn in South America

Flavobacterium group IIb bacteremia: report of a case and review of Flavobacterium infections

“…Flavobacterium meningosepticum was named, identified and characterized by King in 1959 [12] and was mainly implicated as a rare cause of neonatal meningitis appearing in hospital outbreaks as well as sporadic infections [4,12,15,27].…”

“…Meningitis seems to be the most severe type of Flavobacterium infection [2,5,12,[14][15][16]25,30] with four of eight patients dying from this opportunistic disease (Table 5). All patients had significant underlying disease (including tuberculosis in two), and most had circumstantial evidence as to how the organism could have gained access to the meninges (including a recent sterile lumbar puncture in two and rinorrhea in two).…”

“…As these pathogens have been primarily implicated in neonatal meningitis, [4,12,15 ] the type species was designated Flavobacterium meningosepticum [ 12]. Infections in adults are less common and involve a few other species of flavobacteria, as well as Flavobacterium meningosepticum.…”

Flavobacterium meningosepticum infection: an epidemiological study in a newborn nursery.

“…[1][2][3][4][5][6] The infection in babies tends to be severe with a high mortality rate and serious neurological sequelae in the surviving patients. Brody et al1 described two outbreaks of meningitis caused by F. meningosepticum affecting primarily premature infants in a hospital nursery.…”

Flavobacterium meningosepticumfrom cases' of meningitis in Botswana and England

“…meningosepticum has occasionally been isolated from adults, chiefly from debilitated patients (King, 1959;Madruga et al, 1970), and from the genitals of adult patients of both sexes suspected of gonococcal infection (Olsen and Ravn, 1971), but the authors in the latter report did not consider that the strains played a pathogenic role. Werthamer and Weiner (1972) reported a case of subacute bacterial endocarditis, caused by F. meningosepticum, in a patient with rheumatic heart disease.…”