“…Implantable drug delivery systems can provide localized drug release in precisely controlled, patient-specific time sequences with a single administration . By now, various kinds of drug delivery implants have been successfully developed for the treatment of chronic pain, , osteoporosis, retinal diseases, ovarian cancer, prostate cancer, and brain tumor . However, most of the existing implants need to be removed surgically after the treatment period or replaced after the device’s lifetime, which leads to additional costs, secondary injuries, and higher risks of postsurgical complications such as inflammation, infection, and pain.…”