Meningioma associated with Gorlin–Goltz syndrome and a short review of literature

Headache as the presenting manifestation of Gorlin‐Goltz syndrome with diastematomyelia: A case report

“…Potential causes of headache in GGS are (1) intracranial space‐occupying lesions (i.e., meningioma, medulloblastoma, hydrocephalus, choroid plexus tumor, among others); (2) referred pain from odontogenic diseases; (3) thick skull and/or foraminal compression; and (4) psychogenic 3,5–7 …”

“…Potential causes of headache in GGS are (1) intracranial spaceoccupying lesions (i.e., meningioma, medulloblastoma, hydrocephalus, choroid plexus tumor, among others); (2) referred pain from odontogenic diseases; (3) thick skull and/or foraminal compression; and (4) psychogenic. 3,[5][6][7] Regarding headache, in our case, the most probable diagnosis according to ICHD-3 classification was headache attributed to a disorder of cranial bone (11.1), 8 since it was exacerbated by pressure applied to the top part of the cranium and localized to the site of the cranial bone lesions (thickening of the calvaria). Because this patient's headache source was not better accounted for by another ICHD-3 diagnosis, including migraine (it did not have a unilateral location, was not throbbing, aggravated by or causing avoidance of routine physical activity, with no nausea, vomiting, photophobia, and/or phonophobia), tension-type headache (it was exacerbated by pressure applied to the cranial bone), and other primary and secondary headaches.…”