Men with Hypertension are More Likely to Have Severe Lower Urinary Tract Symptoms and Large Prostate Volume

Hwang, Eu Chang; Kim, Sun-Ouck; Nam, Deok-Hyun; Yu, Ho Song; Hwang, In-Sun; Jung, Seung Il; Kang, Taek Won; Kwon, Dong Deuk; Kim, Geun Soo

doi:10.1111/luts.12046

Cited by 38 publications

(32 citation statements)

References 15 publications

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“…Based on current findings and a recent study by Hwang et al (2015) reporting that men with hypertension are more likely to have severe LUTS, a systematic identification and assessment for LUTS, ED, and QoL in poststroke men is recommended. Alternatively, there may be a “hidden” health problem requiring attention.…”

Section: Discussionmentioning

confidence: 97%

Lower Urinary Tract Symptoms, Erectile Dysfunction, and Quality of Life in Poststroke Men: A Controlled Cross-Sectional Study

et al. 2017

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The aim of the current study was to compare lower urinary tract symptoms (LUTS), erectile dysfunction (ED), and quality of life (QoL) in poststroke and healthy men. Thirty poststroke men with stroke-related LUTS, and as controls, 96 healthy men participated in this controlled, cross-sectional study. Participants filled in the Danish Prostate Symptom Score (DAN-PSS-1) Questionnaire, the International Index of Erectile Function (IIEF-5), the 36-Item Short Form (SF-36), the Nocturia Quality-of-Life (N-QoL) Questionnaire. In the age group ≤55 years, comparing poststroke men with healthy controls both with LUTS, the results indicated DAN-PSS-1, total score median 13 (4-17) versus 3 (2-6), p = .05; IIEF-5 25 (14-25) versus 24 (23-25), p = .06; SF-12, total score 499 (360-679) versus 695 (644-734), p = .02; and N-QoL 98 (70-100) versus 96 (90-100), p = .65. In the age group >55 years, comparing poststroke men with healthy controls both with LUTS, the results indicated DAN-PSS-1, total score 13 (8-24) versus 5 (2-7), p < .01; IIEF-5 13 (5-20) versus 25 (24-25), p < .01; SF-36, total score 585 (456-718) versus 742 (687-772), p < .01; and N-QoL, total score 81 (66-95) versus 98 (80-100), p < .01. The results demonstrated that in age group above, but not below 55 years, poststroke men with LUTS had significantly higher frequency of severe and bothersome LUTS and ED than the healthy controls with LUTS, while QoL and N-QoL were significantly lower in comparison. It is recommended to identify and assess older poststroke men for LUTS, ED, and QoL.

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Section: Discussionmentioning

confidence: 97%

Lower Urinary Tract Symptoms, Erectile Dysfunction, and Quality of Life in Poststroke Men: A Controlled Cross-Sectional Study

et al. 2017

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“…In addition to physical activity, other factors associated with increased risk of BPH include diabetes, dyslipidemia, hypertension and obesity. 25–27 Therefore, we included diabetes, dyslipidemia and hypertension as comorbidities for adjustment. Our analyses were generally consistent with previous studies, 25–27 suggesting that dyslipidemia and hypertension were associated with increased risk of BPH.…”

Section: Discussionmentioning

confidence: 99%

“… 25–27 Therefore, we included diabetes, dyslipidemia and hypertension as comorbidities for adjustment. Our analyses were generally consistent with previous studies, 25–27 suggesting that dyslipidemia and hypertension were associated with increased risk of BPH. To avoid bias in the study results, we did not further adjust for obesity because diabetes, dyslipidemia and hypertension are already highly associated with obesity.…”

Section: Discussionmentioning

confidence: 99%

Association between chronic obstructive pulmonary disease and increased risk of benign prostatic hyperplasia: a retrospective nationwide cohort study

et al. 2017

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ObjectiveChronic obstructive pulmonary disease (COPD) and benign prostatic hyperplasia (BPH) are common disorders in ageing male populations. Nevertheless, the relationship between the two diseases has rarely been explored. The objective of this study was to examine whether patients with COPD are at an increased risk of BPH.DesignRetrospective nationwide cohort study.SettingData retrieved from the Taiwan National Health Insurance Research Database.ParticipantsOverall, 19 959 male patients aged 40 years and over with newly diagnosed COPD between 2000 and 2006 were included as the COPD group, and 19 959 sex-matched and age-matched enrollees without COPD were included as the non-COPD group. Both groups were followed-up until the end of 2011.Outcome measuresA Cox proportional hazards regression model was used to compute the risk of BPH in patients with COPD compared with enrollees without COPD.ResultsThe overall incidence rate of BPH was 1.53 times higher in the COPD group than that in the non-COPD group (44.7 vs 25.7 per 1000 person-years, 95% CI 1.46 to 1.60) after adjusting for covariates. An additional stratified analysis revealed that this increased risk of BPH in patients with COPD remained significantly higher than that in enrollees without COPD in all men aged 40 years and over.ConclusionAfter adjustment for covariates, male patients with COPD were found to be at a higher risk of BPH. We suggest that clinicians should be cautious about the increased risk of BPH in male patients with COPD.

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“…One study revealed that diabetes and elevated fasting plasma glucose were associated with BPH 10. In addition, BPH may be an underlying risk factor for cardiovascular disease (CVD) 1112. One matched cohort study by Shah et al .…”

Section: Discussionmentioning

confidence: 99%

Healthcare utilization and costs in patients with benign prostatic hyperplasia: a population-based study

et al. 2016

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This study aimed to investigate differences in healthcare service utilization between patients with and those without benign prostatic hyperplasia (BPH) using Taiwan's National Health Insurance population-based database. A total of 7413 patients with BPH and 7413 age-matched patients without BPH were included. The outcome variable was 1-year utilization of healthcare services including the number of outpatient visits, inpatient days, and the costs of outpatient and inpatient treatments. In addition, we separated healthcare services into urology services and nonurology services for analysis. We found that as to the utilization of outpatient urological services, patients with BPH had more outpatient services (7.84 vs 0.52, P < 0.001), higher outpatient costs (US$372 vs US$34, P < 0.001), a longer length of inpatient stay (0.55 vs 0.11, P < 0.001), higher in-patients costs (US$149 vs US$32, P < 0.001), and higher total costs (US$521 vs US$67, P < 0.001) than the comparison group. As for nonurological services, patients with BPH also had more outpatient services (49.11 vs 24.79, P < 0.001), higher outpatient costs (US$1794 vs US$1014, P < 0.001), a longer length of in-patient stay (3.72 vs 2.04, P < 0.001), higher inpatient costs (US$874 vs US$486, P < 0.001), and higher total costs (US$2668 vs US$1500, P < 0.001) compared to comparison patients. We also found that the average total cost was about 2-fold greater for patients with BPH than comparison patients. We concluded that patients with BPH had higher healthcare utilization than comparison patients without BPH.

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Men with Hypertension are More Likely to Have Severe Lower Urinary Tract Symptoms and Large Prostate Volume

Abstract: Men with hypertension are more likely to have a higher IPSS and large prostate volume than men without hypertension. This finding implicates a pathophysiological association between hypertension and LUTS, and the need to manage comorbid symptoms simultaneously.

Cited by 38 publications

References 15 publications

Lower Urinary Tract Symptoms, Erectile Dysfunction, and Quality of Life in Poststroke Men: A Controlled Cross-Sectional Study

Lower Urinary Tract Symptoms, Erectile Dysfunction, and Quality of Life in Poststroke Men: A Controlled Cross-Sectional Study

Association between chronic obstructive pulmonary disease and increased risk of benign prostatic hyperplasia: a retrospective nationwide cohort study

Healthcare utilization and costs in patients with benign prostatic hyperplasia: a population-based study

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