Membrane Disruption Potential of Doped Cuprous Oxide Nanoparticles Against blaNDM-1 and mcr-1 Positive Colistin Resistant E. coli

Singh, Avinash; Ahmed, Asar; Keshri, Anand Kumar; Arora, Naina; Anjum, Farhan; Rawat, Suraj Singh; Prasad, Amit

doi:10.1007/s12668-021-00850-5

Cited by 2 publications

(2 citation statements)

References 15 publications

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“…This suggests that Cu NPs have a strong antimicrobial effect attributed to their nanoparticle size and better dispersion that facilitates the continuous release of ions from their surface which are absorbed on the bacteria cell membrane due to electrostatic forces and inhibits its replication capability. This was confirmed by other authors [ 57 ] that attributed the antimicrobial mechanism of Cu and G NPs to the bacterial cell membrane disruption by the electrostatic interaction between the cationic charge of Cu and G NPs and the anionic charge of bacterial cellular components. These electrostatic connections increase the oxidative stress that damages bacterial protein as a consequence of cell membrane disruption.…”

Section: Resultssupporting

confidence: 86%

Effect of ionic liquid on graphene decorated with copper nanostructure dispersion towards silicon/graphene/copper composites with enhanced thermal, electrical and antimicrobial properties

Solorzano-Ojeda¹,

Sánchez-Valdés²,

Ramos-deValle³

et al. 2021

Iran Polym J

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Graphic abstract Graphene decorated with cooper nanostructures were prepared with and without ionic liquid (IL) using different milling times. The obtained samples were characterized by Raman, X-ray diffraction (XRD) and transmission electron microscopy (TEM), to analyze the effect of the grinding time on the copper particles adhesion to the graphene sheets. Composites of silicon with two contents of G/Cu, at two weight ratios, nanostructures were prepared and the crosslinking characteristics were analyzed by a rubber process analyzer. The thermal conductivity, electrical resistivity and antimicrobial characteristics against E. coli and S. aureus for these silicon/G/Cu composites were determined. It was found that the use of IL enhances the G/Cu nanostructures dispersion into the silicon polymer matrix with a noticeable improvement in thermal conductivity of 1.12 W/mK for a 7 wt% of G/Cu, a volume electrical resistivity of 4.1 × 10 10 Ω cm with 7 wt% of G/Cu nanoparticles and antimicrobial response of 4.21 ± 0.11 to E. coli and 5.33 ± 0.11 to S. aureus with 7% of G/Cu nanoparticles. It was determined that π–π interactions between graphene and aromatic molecule of IL may be influencing the observed improvement in G/Cu dispersion and final composite performance. The novelty of this work is the use of IL to improve the G/Cu NPs dispersion into the silicon polymer matrix. This silicon/G/Cu composite could be an option to prepare medical devices for electrotherapy or face protection against COVID-19 or other silicon-based devices for medical applications.

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Section: Resultssupporting

confidence: 86%

Effect of ionic liquid on graphene decorated with copper nanostructure dispersion towards silicon/graphene/copper composites with enhanced thermal, electrical and antimicrobial properties

Solorzano-Ojeda¹,

Sánchez-Valdés²,

Ramos-deValle³

et al. 2021

Iran Polym J

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show abstract

“…Several studies have reported on copper nano-/microparticles having an inhibitory effect against microbial and cancer cell growth. [17][18][19] Similarly, iodine-based nano-/microparticles have been shown to be effective in inhibiting microbial and tumour growth. 20,21 Iodine rapidly diffuses into cells through sodium iodide symporters and oxidises proteins, nucleotides, and fatty acids, eventually causing cell death.…”

Section: Introductionmentioning

confidence: 99%

Copper iodide microhexagons: a potential therapeutic agent for surface microbial infection and melanoma

et al. 2023

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Membrane Disruption Potential of Doped Cuprous Oxide Nanoparticles Against blaNDM-1 and mcr-1 Positive Colistin Resistant E. coli

Cited by 2 publications

References 15 publications

Effect of ionic liquid on graphene decorated with copper nanostructure dispersion towards silicon/graphene/copper composites with enhanced thermal, electrical and antimicrobial properties

Effect of ionic liquid on graphene decorated with copper nanostructure dispersion towards silicon/graphene/copper composites with enhanced thermal, electrical and antimicrobial properties

Copper iodide microhexagons: a potential therapeutic agent for surface microbial infection and melanoma

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