Membrane-bound proteases of the gerbil subfornical organ and choroid plexus: an enzyme histochemical study

Topochemistry of Membrane Proteases in Vessels of Guinea Pig Subfornical Organ.

“…These results demonstrate differences in the spectrum of enzymes on vessels of the ChP in comparison to vessels of SFO; and probably also reflect differences in the enzymatic barrier to blood-borne hormones in these two vascular compartments. It should be noted that a similar enzyme cytochemical study was performed in the gerbil (16), showing differences in the distribution and activity levels of the enzymes in comparison to the guinea pig in this present study. The most significant difference between the two species was the distribution of r-GTP in ChP, i. e. , in the guinea pig the vascular endothelium was negative and the epithelium was positive, whereas in the gerbil vascular endothelium was positive and the epithelium was negative.…”