2005
DOI: 10.3201/eid1109.050493
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Abstract: Melioidosis was first recognized in northeastern Brazil in 2003. Confirmation of additional cases from the 2003 cluster in Ceará, more recent cases in other districts, environmental isolation of Burkholderia pseudomallei, molecular confirmation and typing results, and positive serosurveillance specimens indicate that melioidosis is more widespread in northeastern Brazil than previously thought.

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Cited by 86 publications
(74 citation statements)
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References 7 publications
(74 reference statements)
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“…Brazil accounted for the majority (67%) of South American cases (Table 1), with the State of Ceará in northeast Brazil accounting for 91% of cases reported in Brazil. 23,41 Since 2003, there have been 25 cases of melioidosis, including one family cluster, reported in Brazil. This cluster was reported among four siblings, of which three died, from a rural area of Ceará following contact with water after the rainy season.…”
Section: Salvadoran Female Resident Of the United States And Believedmentioning
confidence: 99%
See 1 more Smart Citation
“…Brazil accounted for the majority (67%) of South American cases (Table 1), with the State of Ceará in northeast Brazil accounting for 91% of cases reported in Brazil. 23,41 Since 2003, there have been 25 cases of melioidosis, including one family cluster, reported in Brazil. This cluster was reported among four siblings, of which three died, from a rural area of Ceará following contact with water after the rainy season.…”
Section: Salvadoran Female Resident Of the United States And Believedmentioning
confidence: 99%
“…[12][13][14][15][16][17][18][19][20] Although human-to-human transmission is rare, one reported patient most likely acquired the infection through sexual transmission. 21 In addition, testing of soil samples or water in Peru, 22 Brazil, [22][23][24] Haiti, 22 Venezuela, 25 Ecuador, 25 and Puerto Rico 26 has revealed the presence of B. pseudomallei in the environment in these locations. In one study, B. pseudomallei was recovered from environmental specimens (soap, floor, and shower hose) in a burn unit of a hospital in Belo Horizonte, Brazil.…”
Section: Introductionmentioning
confidence: 99%
“…The first reported case of meliodosis in Brazil was in 2003 in the northeast state of Ceará (12). Afterwards, a few other cases, in non-CF patients, were described in this region (15).…”
Section: Case Reportmentioning
confidence: 99%
“…In Brazil, a cluster of cases was first reported in the Municipality of Tejuçuoca, Ceará state in 2003, when three of four children from the same family died of multiple organ systems failure caused by the infection. 2 Antibody seropositivity can be demonstrated in the healthy population of endemic areas, indicating subclinical infection, 3 and not necessarily a clinically evident disease state. 4 The culture filtrate of B. pseudomallei is rich in secretory antigens mainly composed of exopolysaccharides, lipopolysaccharides (LPS), and proteins and is considered to be a source of antigen for a reliable and sensitive serological method for melioidosis diagnosis in endemic areas.…”
Section: Introductionmentioning
confidence: 99%