Melatonin-enhanced biosynthesis of antimicrobial AgNPs by improving the phytochemical reducing potential of a callus culture of Ocimum basilicum L. var. thyrsiflora

Sumaira,; Khan, Tariq; Abbasi, Bilal Haider; Afridi, Muhammad Siddique; Tanveer, Faouzia; Ullah, Ikram; Bashir, Samina; Hano, Christophe

doi:10.1039/c7ra05044e

Cited by 20 publications

(5 citation statements)

References 66 publications

(64 reference statements)

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“…The results are in agreement with Riaz and coauthors [74] who observed that Melatonin significantly increased TPC values. Similar results were also found by Sumaira and coauthors [75] and Sheshadri and coauthors [76] also reported that Melatonin greatly enhances the biosynthesis of phytochemicals.…”

Section: Total Phenolic Contentsupporting

confidence: 87%

Callus Induction, Proliferation, Enhanced Secondary Metabolites Production and Antioxidants Activity of Salvia moorcroftiana L. as Influenced by Combinations of Auxin, Cytokinin and Melatonin

Bano

Khattak

Basıt

et al. 2022

Braz. arch. biol. technol.

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Tissue culture technique is one of the best methods to reproduce salvia plant Therefore, the aim of this research was to enhance the in-vitro callus proliferation and production of secondary metabolites of S. moorcroftiana using different combinations of auxin, cytokinin and melatonin. Initially, callus induction was optimized using indole acetic acid (IAA), 2, 4-dichlorophenoxy acetic acid (2,4-D), and naphthalene acetic acid (NAA) applied at different concentrations in combination with 1 mg L -1 of 6-benzylaminopurine (BAP). The results indicates that earliest days to callus induction (14.67 days) was occurred in the media fortified HIGHLIGHTS• Tissue culture technique is considered to be one of the best methods to reproduce salvia plant.• Salvia is a medicinal plant with lots of chemical constituents.• Salvia plays an important role in treating different fatal diseases.• Maximum fresh and dry weights were obtained at 1.5 mg L -1 melatonin.• the highest DPPH scavenging activity, total phenolics and flavonoid content were obtained at 1.5 mg L -1 melatonin.

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Section: Total Phenolic Contentsupporting

confidence: 87%

Callus Induction, Proliferation, Enhanced Secondary Metabolites Production and Antioxidants Activity of Salvia moorcroftiana L. as Influenced by Combinations of Auxin, Cytokinin and Melatonin

Bano

Khattak

Basıt

et al. 2022

Braz. arch. biol. technol.

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“…The pasteurization causes Maillard reactions which create more anti-oxidant chemicals and possibly consume less melatonin [ 51 ]. Most importantly, a powerful anti-microorganism activity of melatonin was uncovered during juice storage, although melatonin is a molecule frequently reported to reduce the biotic stress and inhibit the growth of microorganisms in plants [ 75 , 76 , 77 , 78 , 79 , 80 , 81 , 82 , 83 , 84 , 85 ], this effect on food storage was not known, especially in the fresh juice with a shelf life of less than 4 hours. Our results showed that melatonin significantly inhibited the total microorganisms, including bacteria, moulds and yeasts during the juice storage during the tested time from 4 to 12 h ( Figure 7 ).…”

Section: Discussionmentioning

confidence: 99%

Melatonin in Apples and Juice: Inhibition of Browning and Microorganism Growth in Apple Juice

Zhang

Chen

et al. 2018

Molecules

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Synthetic melatonin (N-acetyl-5-methoxytryptamine, MT) is popular in the US and Asian markets as a health supplement. Here, we identified a naturally occurring melatonin source in apple juice. Melatonin was present in all 18 apple cultivars tested. The highest melatonin level of the edible part of apple was detected in the apple peel. The melatonin content in ‘Fuji’ apple juice is comparable to the level of its flesh. Melatonin was consumed during the process of juicing due to its interaction with the oxidants. Melatonin addition significantly reduced the juice color change to brown (browning). The mechanism is that melatonin scavenges the free radicals, which was indicated by the ASBT analysis; therefore, inhibiting the conversion of o-diphenolic compounds into quinones. Most importantly, melatonin exhibited powerful anti-microorganism activity in juice. The exact mechanisms of this action are currently unknown. These effects of melatonin can preserve the quality and prolong the shelf life of apple juice. The results provide valuable information regarding commerciall apple juice processing and storage.

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“…Their versatile implementation spans a multitude of manufacturing processes, encompassing the realms of rubbers, plastics, ceramics, glass, cement, lubricants, paints, ointments, adhesives, sealants, pigments, foods, flame retardants, and even first-aid tapes [17,18]. The advent of the green synthesis method through the employment of plant extracts has captured considerable attention as a viable and simplistic alternative to conventional physical and chemical approaches [19][20][21][22][23][24]. This ecofriendly methodology boasts inherent advantages such as facile handling and the abundant availability of plant resources, positioning it as a highly desirable avenue for scientific exploration [25].…”

Section: Introductionmentioning

confidence: 99%

A Study on the Antibacterial, Antispasmodic, Antipyretic, and Anti-Inflammatory Activity of ZnO Nanoparticles Using Leaf Extract from Jasminum sambac (L. Aiton)

Sugitha,

Venkatesan,

Latha

et al. 2024

Molecules

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The green synthesis of zinc oxide nanoparticles (ZnO NPs) using plants has grown in significance in recent years. ZnO NPs were synthesized in this work via a chemical precipitation method with Jasminum sambac (JS) leaf extract serving as a capping agent. These NPs were characterized using UV-vis spectroscopy, FT-IR, XRD, SEM, TEM, TGA, and DTA. The results from UV-vis and FT-IR confirmed the band gap energies (3.37 eV and 3.50 eV) and the presence of the following functional groups: CN, OH, C=O, and NH. A spherical structure and an average grain size of 26 nm were confirmed via XRD. The size and surface morphology of the ZnO NPs were confirmed through the use of SEM analysis. According to the TEM images, the ZnO NPs had an average mean size of 26 nm and were spherical in shape. The TGA curve indicated that the weight loss starts at 100 °C, rising to 900 °C, as a result of the evaporation of water molecules. An exothermic peak was seen during the DTA analysis at 480 °C. Effective antibacterial activity was found at 7.32 ± 0.44 mm in Gram-positive bacteria (S. aureus) and at 15.54 ± 0.031 mm in Gram-negative (E. coli) bacteria against the ZnO NPs. Antispasmodic activity: the 0.3 mL/mL sample solution demonstrated significant reductions in stimulant effects induced by histamine (at a concentration of 1 µg/mL) by (78.19%), acetylcholine (at a concentration of 1 µM) by (67.57%), and nicotine (at a concentration of 2 µg/mL) by (84.35%). The antipyretic activity was identified using the specific Shodhan vidhi method, and their anti-inflammatory properties were effectively evaluated with a denaturation test. A 0.3 mL/mL sample solution demonstrated significant reductions in stimulant effects induced by histamine (at a concentration of 1 µg/mL) by 78.19%, acetylcholine (at a concentration of 1 µM) by 67.57%, and nicotine (at a concentration of 2 µg/mL) by 84.35%. These results underscore the sample solution’s potential as an effective therapeutic agent, showcasing its notable antispasmodic activity. Among the administered doses, the 150 mg/kg sample dose exhibited the most potent antipyretic effects. The anti-inflammatory activity of the synthesized NPs showed a remarkable inhibition percentage of (97.14 ± 0.005) at higher concentrations (250 µg/mL). Furthermore, a cytotoxic effect was noted when the biologically synthesized ZnO NPs were introduced to treated cells.

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Melatonin-enhanced biosynthesis of antimicrobial AgNPs by improving the phytochemical reducing potential of a callus culture of Ocimum basilicum L. var. thyrsiflora

Abstract: We describe the synthesis of AgNPs using Ocimum basilicum L. var. thyrsiflora leaf derived callus extracts formed in response to thidiazuron alone and a combination of TDZ melatonin which act both as reducing and stabilizing agents.

Cited by 20 publications

References 66 publications

Callus Induction, Proliferation, Enhanced Secondary Metabolites Production and Antioxidants Activity of Salvia moorcroftiana L. as Influenced by Combinations of Auxin, Cytokinin and Melatonin

Callus Induction, Proliferation, Enhanced Secondary Metabolites Production and Antioxidants Activity of Salvia moorcroftiana L. as Influenced by Combinations of Auxin, Cytokinin and Melatonin

Melatonin in Apples and Juice: Inhibition of Browning and Microorganism Growth in Apple Juice

A Study on the Antibacterial, Antispasmodic, Antipyretic, and Anti-Inflammatory Activity of ZnO Nanoparticles Using Leaf Extract from Jasminum sambac (L. Aiton)

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