Melatonin and dopamine mediate the regulation of nitrogen uptake and metabolism at low ammonium levels in Malus hupehensis

Du, Peihua; Yin, Baoying; Zhou, Shasha; Li, Zhongyong; Zhang, Xueying; Cao, Yang; Han, Ruoxuan; Shi, Congjian; Liang, Bowen; Xu, Jin

doi:10.1016/j.plaphy.2022.01.004

Cited by 31 publications

(26 citation statements)

References 48 publications

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“…Interestingly, applying exogenous melatonin promoted root growth and elongation, increased the root absorption area, and improved root vitality. Such changes in root morphology contribute to adaptation to nutrient stress [ 4 ]. In addition, melatonin enhances nutrient transport and accumulation, which in turn affects the distribution of nutrients throughout the plant [ 6 ].…”

Section: Discussionmentioning

confidence: 99%

“…Macroelements (N, P, K, S, Ca, and Mg) and microelements (Fe, Mn, B, Zn, and Cu) play indispensable roles in plant growth and development. For example, a lack of N leads to a decrease in plant chlorophyll content, inhibits photosynthesis, decreases dry-matter accumulation, and alters the root configuration [ 2 , 3 , 4 ]. P deficiency reduces photosynthetic capacity, darkens leaves, causes leaf veins to become purplish-red, increases the root-to-crown ratio, and augments the secretion of organic acids and phenols in roots [ 5 ].…”

Section: Introductionmentioning

confidence: 99%

“…Recent studies have reported that melatonin promotes the absorption and utilization of minerals in plants, thus alleviating the inhibitory effect of abiotic stress on plant yield [ 6 , 19 ]. In a previous study, we revealed that melatonin significantly alleviates the inhibitory effect of NO 3 − and NH 4 + deficiencies by regulating the activity of N metabolic enzymes and expressing N transport and metabolic genes [ 3 , 4 ]. However, the mechanism of how melatonin regulates nutrient stress response is relatively unknown.…”

Section: Introductionmentioning

confidence: 99%

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Ionomic Combined with Transcriptomic and Metabolomic Analyses to Explore the Mechanism Underlying the Effect of Melatonin in Relieving Nutrient Stress in Apple

Cao

et al. 2022

IJMS

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Nutrient stress harms plant growth and yield. Melatonin is a biologically active, multifunctional hormone that relieves abiotic stress in plants. Although previous studies have shown that melatonin plays an important role in improving nutrient-use efficiency, the mechanism of its regulation of nutrient stress remains unclear. In this study, melatonin was applied to apple plants under nutrient stress, and morphological indices, physiological and biochemical indices, and stomatal morphology were evaluated. The response of apple plants to nutrient deficiency and the melatonin mechanism to alleviate nutrient stress were analyzed by combining ionome, transcriptome, and metabolome. The results showed that exogenous melatonin significantly alleviated the inhibitory effect of nutritional stress on the growth of apple plants by regulating stomatal morphology, improving antioxidant enzyme activity, promoting ion absorption, and utilizing and changing the absorption and distribution of minerals throughout the plant. The transcriptome results showed that melatonin alleviated nutrient stress and promoted nutrient absorption and utilization by regulating glutathione metabolism and upregulating some metal ion transport genes. The metabolome results indicated that levels of oxalic acid, L-ascorbic acid, anthocyanins (cyanidin-3-O-galactoside), lignans (lirioresinol A and syringaresinol), and melatonin significantly increased after exogenous melatonin was applied to plants under nutrient stress. These differentially expressed genes and the increase in beneficial metabolites may explain how melatonin alleviates nutrient stress in plants.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Ionomic Combined with Transcriptomic and Metabolomic Analyses to Explore the Mechanism Underlying the Effect of Melatonin in Relieving Nutrient Stress in Apple

Cao

et al. 2022

IJMS

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“…Therefore, melatonin must be studied more widely in the agronomic field in order to be considered a possible input into the NUE strategy [ 12 , 16 , 97 ], including the effects of enhancement by melatonin in the assimilation and metabolization of nitrogen, especially in symbiotic plants [ 54 , 55 ]. It is also important to study the effect of melatonin on rhizosphere and its microbiome, on which there are already some promising data [ 87 , 88 , 89 , 98 , 99 ].…”

Section: Discussionmentioning

confidence: 99%

Role of Melatonin and Nitrogen Metabolism in Plants: Implications under Nitrogen-Excess or Nitrogen-Low

Arnao

Hernández‐Ruíz

Caño

2022

IJMS

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Melatonin is a new plant hormone involved in multiple physiological functions in plants such as germination, photosynthesis, plant growth, flowering, fruiting, and senescence, among others. Its protective role in different stress situations, both biotic and abiotic, has been widely demonstrated. Melatonin regulates several routes in primary and secondary plant metabolism through the up/down-regulation of many enzyme/factor genes. Many of the steps of nitrogen metabolism in plants are also regulated by melatonin and are presented in this review. In addition, the ability of melatonin to enhance nitrogen uptake under nitrogen-excess or nitrogen-low conditions is analyzed. A model that summarizes the distribution of nitrogen compounds, and the osmoregulation and redox network responses mediated by melatonin, are presented. The possibilities of using melatonin in crops for more efficient uptake, the assimilation and metabolization of nitrogen from soil, and the implications for Nitrogen Use Efficiency strategies to improve crop yield are also discussed.

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“…They both significantly promote N uptake and metabolism in plants under drought stress ( Liang et al, 2018a , b ). For example, they promote the uptake and utilization of NO 3 − and NH 4 + in plants under low N stress ( Du et al, 2022a , b ). In addition, they improve the rhizosphere microsphere environment, including soil physical and chemical properties, enzyme activity, and rhizosphere microbial community structure, and also promote nutrient absorption and utilization, thus alleviating the inhibition of plant growth and development under repeated stress ( Li et al, 2018 ; Gao et al, 2021 ).…”

Section: Introductionmentioning

confidence: 99%

Improved tolerance of apple plants to drought stress and nitrogen utilization by modulating the rhizosphere microbiome via melatonin and dopamine

Cao

Yin

et al. 2022

Front. Microbiol.

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This study explored the contributions of melatonin and dopamine to the uptake and utilization of nitrogen and the formation of rhizosphere microbial communities in ‘Tianhong 2’/M. hupehensis, with the goal improving plant resistance to drought stress. Drought stress was formed by artificially controlling soil moisture content. And melatonin or dopamine solutions were applied to the soil at regular intervals for experimental treatment. After 60 days of treatment, plant indices were determined and the structure of the rhizosphere microbial community was evaluated using high-throughput sequencing technology. The findings revealed two ways through which melatonin and dopamine alleviate the inhibition of growth and development caused by drought stress by promoting nitrogen uptake and utilization in plants. First, melatonin and dopamine promote the absorption and utilization of nitrogen under drought stress by directly activating nitrogen transporters and nitrogen metabolism-related enzymes in the plant. Second, they promote the absorption of nitrogen by regulating the abundances of specific microbial populations, thereby accelerating the transformation of the soil nitrogen pool to available nitrogen that can be absorbed directly by plant roots and utilized by plants. These findings provide a new framework for understanding how melatonin and dopamine regulate the uptake and utilization of nitrogen in plants and improve their ability to cope with environmental disturbances.

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Melatonin and dopamine mediate the regulation of nitrogen uptake and metabolism at low ammonium levels in Malus hupehensis

Cited by 31 publications

References 48 publications

Ionomic Combined with Transcriptomic and Metabolomic Analyses to Explore the Mechanism Underlying the Effect of Melatonin in Relieving Nutrient Stress in Apple

Ionomic Combined with Transcriptomic and Metabolomic Analyses to Explore the Mechanism Underlying the Effect of Melatonin in Relieving Nutrient Stress in Apple

Role of Melatonin and Nitrogen Metabolism in Plants: Implications under Nitrogen-Excess or Nitrogen-Low

Improved tolerance of apple plants to drought stress and nitrogen utilization by modulating the rhizosphere microbiome via melatonin and dopamine

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