Melatonin administrated immediately before an intense exercise reverses oxidative stress, improves immunological defenses and lipid metabolism in football players

Maldonado, Mónica; Manfredi, Mark; Ribas-Serna, Juan; García-Moreno, Héctor; Calvo, Juan R.

doi:10.1016/j.physbeh.2011.12.015

Cited by 54 publications

(55 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In fact, while daytime MEL ingestion has shown no beneficial effects on specific performance of soccer, recent studies have shown that diurnal MEL ingestion with a similar dose reduced oxidative stress, and improved immunological responses in soccer players (16). These findings could explain, at least in part, the present study results, about the slight but not significant positive effect of MEL upon 5JT and MAT performances.…”

Section: Discussioncontrasting

confidence: 49%

“…MEL or PLA were ingested in capsule in the morning at 07:30 h, 30 min before starting the test battery, in a double-blind randomized design. Moreover, the 30-min duration between MEL ingestion and exercise was chosen accordingly to the recent finding showing that similar doses of MEL (6 mg), ingested 30 min prior to intense exercise reverses oxidative stress, improves immunological defenses and lipid metabolism in soccer players (16).…”

Section: Participantsmentioning

confidence: 99%

“…Then, cognitive and physical tests were done according to the following order: reaction time, vigilance, MBT, 5JT, HG, and MAT were repeated at three different times of day (08:00 h, 12:00 h and 16:00 h). Tests were chosen based on previous works on cognitive and short-term physical performances specific to soccer players (11,16). All the participants stayed in the laboratory during all the experimental period (i.e., reading books, doing homework).…”

Section: Participantsmentioning

confidence: 99%

See 2 more Smart Citations

Morning melatonin ingestion and diurnal variation of short-term maximal performances in soccer players

Ghattassi¹,

Graja²,

Boudhina³

et al. 2016

Acta Physiologica Hungarica

View full text Add to dashboard Cite

Aim: Very few studies have investigated the temporal specificity of melatonin (MEL) ingestion upon short-term maximal athletic performances. The aim of the present study was to explore the effect of morning MEL ingestion on cognitive and physical performances measured in the afternoon. Methods: Twelve soccer players from a Tunisian squad (17.9 ± 1.3 years, 1.74 ± 0.06 m and 62.0 ± 8.8 kg) participated in the present study. They performed two testing sessions at 08:00 h, 12:00 h and 16:00 h after either MEL (5mg) or placebo (PLA) ingestion, in a randomized order. During each period, the participants performed the following cognitive and physical tests: reaction time and vigilance tests, medicine-ball throw (MBT), five jumps, handgrip strength (HG), and agility tests. Results: cognitive and physical performances were significantly higher at 16:00 h compared to 08:00 h during the two conditions (p < 0.05). Moreover, performances of MBT and HG were lower in the morning with MEL in comparison to PLA (p < 0.05). However, MEL ingestion did not affect physical and cognitive performances measured at 12:00 h and 16:00 h. Conclusion: morning MEL ingestion has no unfavourable effect on afternoon physical and cognitive performances in soccer players.

show abstract

Section: Discussioncontrasting

confidence: 49%

Section: Participantsmentioning

confidence: 99%

Section: Participantsmentioning

confidence: 99%

See 1 more Smart Citation

Morning melatonin ingestion and diurnal variation of short-term maximal performances in soccer players

Ghattassi¹,

Graja²,

Boudhina³

et al. 2016

Acta Physiologica Hungarica

View full text Add to dashboard Cite

show abstract

“…84 In addition, in a nonclinical study of the immediate effect of melatonin in football players, serum concentrations of triglycerides and peroxidized lipids were found to be lower following physical training if 6 mg of melatonin was taken in advance, compared with a placebo group. 85 Regression to the mean might confound the results of some open clinical studies. The regression to the mean phenomenon postulates that abnormal initial values tend to shift automatically towards the population norm at remeasurement, without any specific interventions.…”

Section: Effect Of Melatonin On Lipidsmentioning

confidence: 99%

“…The degree of oxidation of LDL particles would probably be a better index of the effect of melatonin than lipid concentrations. 85,90,91 Further, it is likely that only very high supraphysiological doses of melatonin could demonstrate an antioxidant effect in vivo.…”

Section: Effect Of Melatonin On Lipidsmentioning

confidence: 99%

Melatonin and its use in atherosclerosis and dyslipidemia

Danilenko¹,

Ragino²

2013

CPT

View full text Add to dashboard Cite

A review of pineal melatonin synthesis, regulation, and physiological effects indicates that not only does melatonin act as a hormonal signal of darkness, but also that it possesses antioxidant and anti-inflammatory properties. Although oxidation and inflammation play a pivotal role in atherogenesis, no studies have investigated administration of melatonin for human arterial atherosclerosis. However, 13 clinical trials have investigated use of melatonin in dyslipidemia, which is a close correlate of atherosclerosis. The results of these clinical trials, particularly the five that are placebo-controlled, are inconclusive as to whether melatonin can normalize the blood lipid profile. Significant confounders in these studies might be a phase shift of the cholesterol rhythm by melatonin, a posture effect at venipuncture, uncontrolled diet during the course of melatonin intake, and the phenomenon of regression to the mean. Thus, future studies are required, which should also consider use of higher doses of melatonin and/or measurement of oxidized forms of cholesterol-containing particles (which are the most aggressive in relation to atherogenesis) in addition to lipidic fractions.

show abstract

The melatonin contained in beer can provide health benefits, due to its antioxidant, anti‐inflammatory and immunomodulatory properties

2022

View full text Add to dashboard Cite

Beer is a fermented beverage with a low alcohol content originating from cereal fermentation (barley or wheat). It forms part of the diet for many people. It contains melatonin (N‐acetyl‐5‐methoxytryptamine). Melatonin is a molecule with a wide range of antioxidant, oncostatic, immunomodulatory, and cytoprotective properties. The aim of this work was to review the data supporting the idea that a moderate consumption of beer, because of its melatonin content, is particularly useful in healthy diets and in other physiological situations (such as pregnancy, menopause, and old age). Data source: a) The MEDLINE /PubMed search was conducted from 1975 to April 2022, and b) Our own experience and published studies on melatonin, the immune system, and beer. We provide a review of research on the mechanisms of melatonin generation in beer, its concentrations, and its possible effects on health. The melatonin contained in beer, as part of a healthy diet and in some special physiological situations, could act as a protective factor and improve the quality of life of those who drink it in moderation. © 2022 The Authors. Journal of The Science of Food and Agriculture published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.

show abstract

Melatonin administrated immediately before an intense exercise reverses oxidative stress, improves immunological defenses and lipid metabolism in football players

Cited by 54 publications

References 33 publications

Morning melatonin ingestion and diurnal variation of short-term maximal performances in soccer players

Morning melatonin ingestion and diurnal variation of short-term maximal performances in soccer players

Melatonin and its use in atherosclerosis and dyslipidemia

The melatonin contained in beer can provide health benefits, due to its antioxidant, anti‐inflammatory and immunomodulatory properties

Contact Info

Product

Resources

About