Melasma in men: a clinical, aetiological and histological study

Sarkar, Rashmi; Puri, Poonam; Rk, Jain; Singh, Abhay; Desai, Alpesh

doi:10.1111/j.1468-3083.2009.03524.x

Cited by 86 publications

(113 citation statements)

References 14 publications

(42 reference statements)

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“…Another case control study conducted by Jie et al, 1999[9]on female patients of melasma to evaluate the serum levels of trace elements showed higher levels of iron and copper in female patients of melasma as compared to the controls. Sarkar R et al, 2010 [10] conducted a study to assess the clinical, etiological and histological features of melasma in men. Laboratory investigations revealed anemia in 12.2% patients.…”

Section: Discussionmentioning

confidence: 99%

Serum Iron profile in Female patients of Melasma-A case control study

Qazi¹,

Dogra²,

Dogra³

2017

APJHS

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Background: Melasma is a common acquired pigmentary dermatosis characterized by presence of symmetric, hyperpigmented patches, most commonly seen on the face. It is most commonly seen in young to middle aged females. The exact cause of melasma is not known, however a number of factors have been implicated in its etiopathogenesis. The effect of body iron stores on melasma is not exactly known. Although iron overload has been seen to affect skin pigmentation, effect of low body iron stores on skin pigmentation is unknown. In this study, we evaluated total body iron stores by assessing serum iron , ferritin and total iron binding capacity (TIBC) level among nonpregnant females with and without melasma. Materials and Methods: A cross-sectional case control study was conducted in 2016 at Department of Dermatology, Government Medical College, Jammu for a period of one year. The study comprised of 70 non pregnant females with and without melasma . Serum iron level, TIBC and ferritin in the two groups were measured and compared. The severity of melasma was assessed on the basis of MASI score. The correlation between severity of melasma and derangements in iron profile were also assessed in the study. Results: Comparison of serum Iron levels in cases and controls showed lower levels in patients of melasma(58.84± 29.17) as compared to control population (82.26± 45.83) ;p<0.001. Serum ferritin levels were found to be lower in patients of melasma (20.06±18.64) as compared tp control population(42.29±30.08);p<0.001.Comparison of serum TIBC between cases and controls showed higher values in cases(424±58 98.33) compared to control population (384.45± 74.55) p<0.007.Also a positive correlation was found between severity of melasma as per MASI score and derangement in Iron profile. Conclusion: Serum Iron, ferritin levels were found to be significantly lower in patients of melasma compared to the control population whereas Total iron binding capacity(TIBC) was found to be higher in patients of melasma compared to the control population indicating low body iron storesin patients of melasma. The severity of maelasma as per MASI score correlated well with the derangements in iron profile. Hence patients with melasma had low body Iron stores compared to control population indicating a possible role of iron deficiency in the etiopathogenesis of melasma.

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Section: Discussionmentioning

confidence: 99%

Serum Iron profile in Female patients of Melasma-A case control study

Qazi¹,

Dogra²,

Dogra³

2017

APJHS

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“…36 patients (43.9%) ( Table 2) were found to have pigmentation at the eyebrow and superciliary region out of which 5 (13.89%) were men and 31 (86.11%) were women. Among patients with superciliary pigmentation, most common pattern seen was centrofacial -24 (66.67%) followed by malar (33.33%) [4]. patients within the superciliary subset also exhibited pigmentation extending from the inferior border of the eyebrows to the upper eyelids.…”

Section: Resultsmentioning

confidence: 99%

“…The most common hyperpigmentary disorder affecting Indian population, it is frequently observed in women of Fitzpatrick skin types III to V and has a significant negative impact on patients' quality of life [1][2][3]. Traditionally considered a malady affecting only women, men have shown to constitute significant proportion (20.5%) of all melasma patients in Indian population [4]. Although the exact underlying etiology for melasma is unclear, well known risk factors include genetic predisposition, exposure to ultraviolet light, pregnancy, and exogenous hormones (i.e.…”

Section: Introductionmentioning

confidence: 99%

Melasma: Presence of Pigmentation at Superciliary Location

S¹

2014

Pigmentary Disorders

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“…Study by Sarkar et al documented melasma in 20% males which was higher than present study. 5 Various etiological agents that attributes to melasma include sun exposure, genetic factors, use of cosmetics, pregnancy, hormone replacement therapy, use of oral contraceptives etc. 6 In present study, sun exposure was observed in 84% patients, cosmetic use in 58% patients and 41% patients gave the history of oral drug intake, out of which 8 females gave the history of oral contraceptive pills intake.…”

Section: Discussionmentioning

confidence: 99%

A clinico-dermatoscopic study of 100 cases of melasma in a tertiary care hospital

Kaur

Sharma

et al. 2018

Int J Res Dermatol

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Background: Melasma is one of the most common hyperpigmentary disorders seen among Indian patients. Dermatoscope is a non-invasive tool that helps in visualization of surface and sub-surface changes. Recognition of characteristic dermatoscopic patterns of melasma helps in differentiating it from other hyperpigmentary disorders. The present study was carried out to study clinical and dermatoscopic patterns of melasma.Methods: A total of 100 patients with clinical diagnosis of melasma were enrolled in this study. These patients were first examined clinically and then under dermatoscope. All the findings were recorded.Results: Out of total 100 patients, 91 were females and 9 were males. Mean age of presentation was 34.86 years. Malar distribution pattern was the most common pattern observed in 54% patients. On dermatoscopic examination, 58% cases had epidermal melasma, 23% had dermal melasma and 19% had mixed melasma. Accentuated pseudoreticular network was the most common pattern seen in 88% cases.Conclusions: Melasma is a distressing hyperpigmentary disorder. Dermatoscope helps in diagnosis and prognosis of melasma. Therapeutic efficacy of various modalities can be monitored using dermatoscope. It has reduced the need of invasive interventions like biopsy from face for histopathology.

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Melasma in men: a clinical, aetiological and histological study

Abstract: Melasma is frequently observed in Indian men. The main causative factors among the male patients appeared to be sun-exposure and family history. Melasma in men is definitely less common than in women, but shares the same clinicohistopathological characteristics as in women.

Cited by 86 publications

References 14 publications

Serum Iron profile in Female patients of Melasma-A case control study

Serum Iron profile in Female patients of Melasma-A case control study

Melasma: Presence of Pigmentation at Superciliary Location

A clinico-dermatoscopic study of 100 cases of melasma in a tertiary care hospital

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