Melanotic neuroectodermal tumor of infancy: Review of the literature and report of a case

Metastatic Melanotic Neuroectodermal Tumor of Infancy: Report of a Case and Review of the Literature

“…1 However, recurrences may be difficult to distinguish from the aggressive growth of residual tumor. 20 Of the 11 identified mandibular MNTI cases identified in one review, 3 had recurrences. 1 In another 2015 review of all head and neck MNTI sites including 35 mandibular cases, age was an important association: tumor seen prior to 2 months of age was associated with quadruple the recurrence rate compared to after 4.5 months of age.…”

Melanotic Neuroectodermal Tumor of Infancy: A Systematic Review

“…4,7,[12][13][14][15][16] In addition, data were collected on 356 additional cases that were reported in the literature from 1918 through 2004 from 3 major systematic reviews. 18,81,82 These cases were combined with the 116 cases published from January 2005 through December 2013 (Supplementary Table 1) to constitute a total of 472 cases for analysis. This analysis included gender, age at diagnosis, tumor site, and disease recurrence.…”

Melanotic neuroectodermal tumor in a newborn

“…However, the present case as a newborn is one of the patients with MNTI who were diagnosed at earliest time in the literature because the entity usually manifests between the ages of 3 and 9 months [3]. Predicting recurrence and high aggressive behavior of the tumor is not yet possible.…”

“…However, electron microscopy, laboratory data, and immunohistochemistry indicate its neuroectodermal origin. So far, approximately 200 cases have been reported in the medical literature [3].…”