Melanosis of the ileum

Melanosis Ilei Associated with Chronic Ingestion of Oral Iron

“…In contrast, melanosis ilei without melanosis coli is not associated with the use of laxatives, as in our case. Melanosis ilei without melanosis coli, endoscopically, shows grayish-black or brownish-black punctuate pigmentations in the ileal mucosa, which does not extend beyond the ileocecal valve like our case 2-6…”

“…However, a variety of compounds may cause dark pigmentation of the intestine. Melanosis coli is not uncommon, however, very few cases of melanosis ilei are described in the literature 2-5. Melanosis ilei may be recognized with or without melanosis coli 2.…”

“…Melanosis coli is not uncommon, however, very few cases of melanosis ilei are described in the literature 2-5. Melanosis ilei may be recognized with or without melanosis coli 2. Melanosis ilei combined with melanosis coli should be differentiated because it cannot be ascertained that the terminal ileum and other parts of the small intestine are never affected in melanosis coli 1,6.…”

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“…Melanosis of the colon is not uncommon and has been associated with the ingestion of anthraceneline laxatives, although it can be observed in patients without such history [ 3 ]. Melanosis of the small intestine is an extremely rare finding with only a few cases described in the literature [ 1 , 2 , 4 ]. Melanosis of the duodenum has been associated with several conditions such as chronic renal failure, gastrointestinal bleeding, ingestion of drugs, or folic acid deficiency [ 1 , 2 ].…”

“…Melanosis of the duodenum has been associated with several conditions such as chronic renal failure, gastrointestinal bleeding, ingestion of drugs, or folic acid deficiency [ 1 , 2 ]. There is only one reported case of melanosis of the jejunum, possibly due to ferrous-sulfate administration and vitamin deficiencies [ 2 ], and very few cases of melanosis in the ileum [ 2 , 4 ]. In the majority of these cases, the pigment was characterized as hemosiderin and/or lipofuscin.…”