Meeting the requirements of halal gelatin: A mini review

Rakhmanova, Aizhan; Khan, Zaid Ashiq; Sharif, Rahat

doi:10.15406/mojfpt.2018.06.00209

Cited by 29 publications

(22 citation statements)

References 43 publications

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“…fish skin or bone) has emerged as an alternative to those from mammalian sources [14,15,16]. Fish gelatin has characteristics similar to porcine gelatin, however, it (especially cold water fish gelatin) has a low gelling point below 10 °C with low viscosity whereas mammalian gelatin would remain as the gel state at room temperature with high viscosity [14,15,16]. These distinct gelling behavior of fish gelatin promote the advancement of injectable technologies for the systemic administration and can improve in vivo release [17].…”

Section: Introductionmentioning

confidence: 99%

Nanogels Derived from Fish Gelatin: Application to Drug Delivery System

et al. 2019

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The gelatin extracted from mammals of porcine and bovine has been prominently used in pharmaceutical, medical, and cosmetic products. However, there have been some concerns for their usage due to religious, social and cultural objections, and animal-to-human infectious disease. Recently, gelatin from marine by-products has received growing attention as an alternative to mammalian gelatin. In this study, we demonstrate the formation of nanogels (NGs) using fish gelatin methacryloyl (GelMA) and their application possibility to the drug delivery system. The fabrication of fish GelMA NGs is carried out by crosslinking through the photopolymerization of the methacryloyl substituent present in the nanoemulsion droplets, followed by purification and redispersion. There were different characteristics depending on the aqueous phase in the emulsion and the type of solvent used in redispersion. The PBS-NGs/D.W., which was prepared using PBS for the aqueous phase and D.W. for the final dispersion solution, had a desirable particle size (<200 nm), low PdI (0.16), and high drug loading efficiency (77%). Spherical NGs particles were observed without aggregation in TEM images. In vitro release tests of doxorubicin (DOX)-GelMA NGs showed the pH-dependent release behavior of DOX. Also, the MTT experiments demonstrated that DOX-GelMA NGs effectively inhibited cell growth, while only GelMA NGs exhibit higher percentages of cell viability. Therefore, the results suggest that fish GelMA NGs have a potential for nano-carrier as fine individual particles without the aggregation and cytotoxicity to deliver small-molecule drugs.

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Section: Introductionmentioning

confidence: 99%

Nanogels Derived from Fish Gelatin: Application to Drug Delivery System

et al. 2019

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“…Gelatin is a commonly used ingredient with many applications in the food and pharmaceutical industries (32) and is generally produced from the skin and bones from pigs and cattle. Data from gelatin manufacturers in Europe indicate that the major source of edible gelatin is pork skin (80% of gelatin products) (40).…”

Section: Discussionmentioning

confidence: 99%

Postmarket Laboratory Surveillance for Forbidden Substances in Halal-Certified Foods in Thailand

Mahama

Waloh

Chayutsatid

et al. 2020

Journal of Food Protection

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Limited information exists regarding adulteration of Halal-certified food by substances forbidden under Islamic law (Haram substances). This study was conducted using forensic laboratory testing to investigate the prevalence of this type of adulteration. In this large-scale survey of Halal-certified food products randomly collected from markets in Thailand, 4,829 food samples from 10 food groups were tested in the laboratory for four potentially Haram substances: porcine DNA, porcine fatty acids, ethanol, and hydroxyproline (gelatin). No samples were adulterated with porcine DNA or fatty acids. However, 62 samples (approximately 1.3%) were positive for ethanol (>0.5% for non–naturally fermented products and >1% for naturally fermented products). The hydroxyproline concentration in the samples was compared with that of a negative control. Gelatin, as indicated by the presence of hydroxyproline, was the major suspicious substance found in these products. Further investigations are required to determine whether the gelatin is of Halal origin. These results from this first large-scale postmarket surveillance of Halal-certified food products for forbidden substances reveals the important role of forensic laboratory testing for supporting Halal supervision and certification. These findings provide useful information for government agencies seeking to encourage Halal compliance by food enterprises and for Muslim consumers and Halal food importers and exporters. HIGHLIGHTS

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“…It is isolated from waste products of the meat industry, such as the collagen-rich bones, skin, tendons, and hooves of animals [ 58 ]. Typically, collagen is converted to gelatin by heating in a strong acid or alkaline solution at high temperatures (e.g., 80 °C) [ 59 ]. The gelatin obtained from this process is purified and then converted into a powdered form that is used as a functional ingredient in the food and other industries.…”

Section: Overview Of Biodegradable Packaging Materialsmentioning

confidence: 99%

Recent Advances in the Development of Smart and Active Biodegradable Packaging Materials

et al. 2021

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Interest in the development of smart and active biodegradable packaging materials is increasing as food manufacturers try to improve the sustainability and environmental impact of their products, while still maintaining their quality and safety. Active packaging materials contain components that enhance their functionality, such as antimicrobials, antioxidants, light blockers, or oxygen barriers. Smart packaging materials contain sensing components that provide an indication of changes in food attributes, such as alterations in their quality, maturity, or safety. For instance, a smart sensor may give a measurable color change in response to a deterioration in food quality. This article reviews recent advances in the development of active and smart biodegradable packaging materials in the food industry. Moreover, studies on the application of these packaging materials to monitor the freshness and safety of food products are reviewed, including dairy, meat, fish, fruit and vegetable products. Finally, the potential challenges associated with the application of these eco-friendly packaging materials in the food industry are discussed, as well as potential future directions.

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Meeting the requirements of halal gelatin: A mini review

Cited by 29 publications

References 43 publications

Nanogels Derived from Fish Gelatin: Application to Drug Delivery System

Nanogels Derived from Fish Gelatin: Application to Drug Delivery System

Postmarket Laboratory Surveillance for Forbidden Substances in Halal-Certified Foods in Thailand

Recent Advances in the Development of Smart and Active Biodegradable Packaging Materials

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