Medium effects on fluorescence of ciprofloxacin hydrochloride

Yang, Rui; Fu, Yan; Li, Long-Di; Liu, Jiaming

doi:10.1016/s1386-1425(03)00059-3

Cited by 27 publications

(23 citation statements)

References 9 publications

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“…Interestingly, the trend of the fluorescence intensities at their maxima against pH obs is opposite to that of non‐derivatized ciprofloxacin. Ciprofloxacin emits most intensively under acidic‐to‐neutral conditions (pH 2–7), while being non‐emissive under basic conditions . The pH‐dependent emission of amidine CIP‐1 showed different distinct regions (Figure B), which can be put in relation to the p K a s of the fluorophore's groups taking into account general principles of structure‐fluorescence relationships of fluoroquinolones.…”

Section: Resultsmentioning

confidence: 99%

Impact of Hydrogen Bonding on the Fluorescence of N‐Amidinated Fluoroquinolones

Xie

Manuguri

Ramström

et al. 2019

Chemistry An Asian Journal

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The fluorescence properties of AIE‐active N‐amidinated fluoroquinolones, efficiently obtained by a perfluoroaryl azide–aldehyde–amine reaction, have been studied. The fluorophores were discovered to elicit a highly sensitive fluorescence quenching response towards guest molecules with hydrogen‐bond‐donating ability. This effect was evaluated in a range of protic/aprotic solvents with different H‐bonding capabilities, and also in aqueous media. The influence of acid/base was furthermore addressed. The hydrogen‐bonding interactions were studied by IR, NMR, UV/Vis and time‐resolved fluorescence decay, revealing their roles in quenching of the fluorescence emission. Due to the pronounced quenching property of water, the N‐amidinated fluoroquinolones could be utilized as fluorescent probes for quantifying trace amount of water in organic solvents.

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Section: Resultsmentioning

confidence: 99%

Impact of Hydrogen Bonding on the Fluorescence of N‐Amidinated Fluoroquinolones

Xie

Manuguri

Ramström

et al. 2019

Chemistry An Asian Journal

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“…). CPFX shows a conjugated effect between the hydroxyl group and P‐π conjugation of the quinolone ring, making CPFX intensely fluorescent . Thus, at the end of the photocatalytic test the CPFX presents high fluorescence intensity.…”

Section: Resultsmentioning

confidence: 99%

Sonochemical synthesis of CaBi₆O₁₀nanoplates: photocatalytic degradation of organic pollutants (ciprofloxacin and methylene blue) and oxidizing species study (h⁺, OH·, H₂O₂and O₂^•-)

Montalvo-Herrera

Sánchez-Martínez

Torres-Martı́nez

2017

J. Chem. Technol. Biotechnol

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BACKGROUND CaBi6O10 nanoplates were synthesized by a sonochemical method using a high‐power ultrasonic processor. Also, the CaBi6O10 was synthesized by an impregnation‐calcination method in order to compare the effect of the synthesis method on the photocatalytic activity of the photocatalyst. In addition, the role of the oxidizing species such as h+, OH•, H2O2 and O2•‐ was evaluated during the photocatalytic degradation of ciprofloxacin (CPFX) and methylene blue (MB). RESULTS The sample synthesized sonochemically showed a morphology of nanoplates with a thickness around 50 nm and length 1.5 µm. Also, the sample showed the best photocatalytic activity (i.e. the sample with the highest surface area and a plate‐like morphology), degrading CPFX by 56% and MB by 67%. The main species involved in the degradation of CPFX were the OH· radicals, and in the degradation of MB it was H2O2. CONCLUSIONS CaBi6O10 nanoplates were prepared successfully by a sonochemical method, showing the best photocatalytic activity in the degradation of CPFX and MB, mainly attributed to the morphology of the nanoplates. In addition, it was observed that the main species involved in the degradation of CPFX were the OH· radicals and in the degradation of MB, H2O2. © 2017 Society of Chemical Industry

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“…In China, SAR was approved in 2001 as a national second group new medicine and market feedback for this product has been good. At different pH environments, quinolone molecules exhibit different spectral behaviors . Comprehensive investigation of the spectral properties of quinolone molecules has important significance for its application.…”

Section: Introductionmentioning

confidence: 99%

Fluorescence spectra, fluorescence quantum yield and dissociation constant of sarafloxacin

Liu

Duan

et al. 2016

Luminescence

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In this study, the fluorescence spectra of sarafloxacin (SAR) under different pH conditions were investigated to determine the structural changes due to protonation that result from change in pH. At pH < 1.02, SAR exists in the H L form for which the maximum fluorescence emission wavelength was about 455 nm. At pH 1.87-4.94, SAR exists in the H L form in which H L loses one proton in the nitrogen molecule at the 1-position in the quinoline ring. Fluorescence intensity was strong and steady and the maximum emission wavelength was 458 nm. At pH 7.14-9.30, the maximum emission wavelengths were gradually blue shifted to 430 nm with increase in pH, here SAR exists in the form of a bipolar ion HL in which H L loses a carboxyl group proton. At pH > 11.6, HL transforms into anionic L in which HL loses one proton from the piperazine ring, leading to a decrease in fluorescence intensity, and the maximum emission wavelength was red shifted to approximately 466 nm. The two-step dissociation constant pKa for SAR was calculated, pK was 6.06 ± 0.37 and pK for SAR was 10.53 ± 0.19. In a pH 3.62 buffer solution with quinine sulfate as the reference, the fluorescence quantum yield of SAR at the maximum excitation wavelength of 276 nm was 0.09.

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Medium effects on fluorescence of ciprofloxacin hydrochloride

Cited by 27 publications

References 9 publications

Impact of Hydrogen Bonding on the Fluorescence of N‐Amidinated Fluoroquinolones

Impact of Hydrogen Bonding on the Fluorescence of N‐Amidinated Fluoroquinolones

Sonochemical synthesis of CaBi₆O₁₀nanoplates: photocatalytic degradation of organic pollutants (ciprofloxacin and methylene blue) and oxidizing species study (h⁺, OH·, H₂O₂and O₂^•-)

Fluorescence spectra, fluorescence quantum yield and dissociation constant of sarafloxacin

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Medium effects on fluorescence of ciprofloxacin hydrochloride

Cited by 27 publications

References 9 publications

Impact of Hydrogen Bonding on the Fluorescence of N‐Amidinated Fluoroquinolones

Impact of Hydrogen Bonding on the Fluorescence of N‐Amidinated Fluoroquinolones

Sonochemical synthesis of CaBi6O10nanoplates: photocatalytic degradation of organic pollutants (ciprofloxacin and methylene blue) and oxidizing species study (h+, OH·, H2O2and O2•-)

Fluorescence spectra, fluorescence quantum yield and dissociation constant of sarafloxacin

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Sonochemical synthesis of CaBi₆O₁₀nanoplates: photocatalytic degradation of organic pollutants (ciprofloxacin and methylene blue) and oxidizing species study (h⁺, OH·, H₂O₂and O₂^•-)