Meditation reduces brain activity in the default mode network in children with active cancer and survivors

Hehr, Aneesh; Iadipaolo, Allesandra; Morales, Austin; Cohen, Carl M.; Taub, Jeffrey W.; Harper, Felicity W. K.; Goldberg, Elimelech; Bluth, Martin H.; Rabinak, Christine A.; Marusak, Hilary A.

doi:10.1002/pbc.29917

Cited by 3 publications

(4 citation statements)

References 72 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These relationships were not explained fully by age ( Tables S3 and S4 ). As there was a relatively small range of ages (12–15) and a wider range of pubertal development, pubertal development was included as a covariate in further analyses.…”

Section: Resultsmentioning

confidence: 99%

“…As there was a relatively small range of ages (12)(13)(14)(15) and a wider range of pubertal development, pubertal development was included as a covariate in further analyses.…”

Section: Self-report and Demographicsmentioning

confidence: 99%

“…Despite the value of trait mindfulness for emotional well-being, little is known about the neural correlates of trait mindfulness in children and young adolescents (in contrast to numerous studies of adults; (14)). Three studies in children and adolescents have examined trait mindfulness correlates with task-based functional magnetic resonance imaging (fMRI activations) (15,16) and structural MRI (17). In consideration of traits that are supposedly consistent across contexts, resting-state fMRI is appealing because it measures functional connectivity of brain regions and networks that are independent of specific task demands.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Dynamic functional connectivity correlates of trait mindfulness in early adolescence

Treves,

Marusak,

Decker

et al. 2024

Preprint

View full text Add to dashboard Cite

Background: Trait mindfulness, the tendency to attend to present-moment experiences without judgement, is negatively correlated with adolescent anxiety and depression. Understanding the neural mechanisms underlying trait mindfulness may inform the neural basis of psychiatric disorders. However, few studies have identified brain connectivity states that correlate with trait mindfulness in adolescence, nor have they assessed the reliability of such states. Methods: To address this gap in knowledge, we rigorously assessed the reliability of brain states across 2 functional magnetic resonance imaging (fMRI) scan from 106 adolescents aged 12 to 15 (50% female). We performed both static and dynamic functional connectivity analyses and evaluated the test-retest reliability of how much time adolescents spent in each state. For the reliable states, we assessed associations with self-reported trait mindfulness. Results: Higher trait mindfulness correlated with lower anxiety and depression symptoms. Static functional connectivity (ICCs from 0.31-0.53) was unrelated to trait mindfulness. Among the dynamic brains states we identified, most were unreliable within individuals across scans. However, one state, an hyperconnected state of elevated positive connectivity between networks, showed good reliability (ICC=0.65). We found that the amount of time that adolescents spent in this hyperconnected state positively correlated with trait mindfulness. Conclusions: By applying dynamic functional connectivity analysis on over 100 resting-state fMRI scans, we identified a highly reliable brain state that correlated with trait mindfulness. The brain state may reflect a state of mindfulness, or awareness and arousal more generally, which may be more pronounced in those who are higher in trait mindfulness.

show abstract

Section: Resultsmentioning

confidence: 99%

“…As there was a relatively small range of ages (12)(13)(14)(15) and a wider range of pubertal development, pubertal development was included as a covariate in further analyses.…”

Section: Self-report and Demographicsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Dynamic functional connectivity correlates of trait mindfulness in early adolescence

Treves,

Marusak,

Decker

et al. 2024

Preprint

View full text Add to dashboard Cite

show abstract

“…Using neuroimaging, we found that greater trait mindfulness was associated with lower anxiety and increased markers of neural flexibility in children (Marusak et al, 2018). We also found that active meditation, such as focused attention to the breath, was associated with lower activity in the brain's default mode network, which is implicated in distress and rumination, in children with cancer (Hehr et al, 2022).…”

Section: Mind–body Interventions: the “What” “How” And “Why”mentioning

confidence: 94%

Strong mind, strong body: The promise of mind–body interventions to address growing mental health needs among youth

Grasser

Marusak

2023

Mental Health Science

Self Cite

View full text Add to dashboard Cite

As the prevalence of childhood and adolescent anxiety, depression, and other mental health concerns continues to rise, there has been an unprecedented increase in support of mind-body practices like yoga, dance, meditation, mindfulness, aerobic exercise, and more-in part driven by the mental health burden imposed by the COVID-19 pandemic.While a growing body of evidence supports the safety and effectiveness of mind-body approaches, gaps in funding for and empirical research on mechanistic underpinnings, methodology development to assess multicomponent therapeutic practices, dissemination and implementation, and diversity in researchers, practitioners, and recipients remain. As a consequence, the neurobiological impacts of mind-body techniques are not well understood nor broadly accepted as standard forms of care by clinicians and insurers-often being considered as "alternative" rather than "complementary" or "integrative." In this commentary, we summarize work from our labs and others highlighting the promise of mind-body approaches for improving mental health in youth, in line with the National Institute of Mental Health's strategic plan to address health disparities. We offer a potential framework for implementation and research-the Expressive Therapies Continuum. We also propose solutions to key research and policy gaps, that by could have positive public health impacts for those who are struggling and to prevent emergence of psychiatric illness, especially in developing youth.

show abstract

Exploring volunteers’ role in healthcare service ecosystems: value co-creation, self-adjustment and re-humanisation

Di Pietro,

Ungaro,

Renzi

et al. 2024

JOSM

View full text Add to dashboard Cite

Purpose The paper investigates how the engagement of a group of actors (the volunteers), previously unexplored in service ecosystems literature, contributes to generating new co-creation activities and well-being outcomes in the healthcare service ecosystem (HSE). Moreover, the study analyses how the provision and integration of volunteers’ resources help to explain the HSE self-adjustment favouring the re-humanisation of service.Design/methodology/approach The article zooms in on the volunteers’ activities in an HSE. A qualitative approach is adopted, and an empirical investigation is grounded in data gathered from Kids Kicking Cancer (KKC) Italia, a volunteer association operating in the paediatric oncology ward of Italian hospitals. Data are collected and triangulated through in-depth interviews, volunteers’ diaries and observations. The analysis is conducted by adopting an interpretative thematic analysis technique.Findings The study provides a conceptual framework explaining how volunteers’ value co-creation activities influence the HSE’s self-adjustment by leading to a re-humanisation of services. The paper also contributes to the state of knowledge by identifying seven categories of volunteers’ value co-creation activities, two of which are completely new in the literature (co-responsibility and empowerment).Originality/value The paper contributes to the service research literature by identifying empirically grounded value co-creation activities extending the understanding of self-adjustment and re-humanisation of the service ecosystem.

show abstract

Meditation reduces brain activity in the default mode network in children with active cancer and survivors

Cited by 3 publications

References 72 publications

Dynamic functional connectivity correlates of trait mindfulness in early adolescence

Dynamic functional connectivity correlates of trait mindfulness in early adolescence

Strong mind, strong body: The promise of mind–body interventions to address growing mental health needs among youth

Exploring volunteers’ role in healthcare service ecosystems: value co-creation, self-adjustment and re-humanisation

Contact Info

Product

Resources

About