Medicine use in children aged under 12 years—Population survey in <scp>F</scp>inland

Kesti, Joonas; Saastamoinen, Leena; Lavikainen, Piia; Sepponen, Kati

doi:10.1002/pds.5539

Cited by 4 publications

(1 citation statement)

References 32 publications

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“…2018 ). Previous statistical analyses have shown that the current situation of children’s medication use has few specifications of special dosage forms, lack of varieties, unclear information about children’s instructions, and off-label drug use ( Kesti et, al. 2023 ; Chen, et, al.…”

Section: Introductionmentioning

confidence: 99%

Real-world data for the availability of pediatric medicines in Chinese hospitals: a multi-center survey and analysis

Ruan,

Chen,

Cai

et al. 2024

Front. Pharmacol.

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Aim: No information exists on the availability of pediatric medicines in China. This study aimed to access the availability of different types of pediatric medicine and determine their ratio in medical institution drug catalogs.Methods: Based on drug instructions, an expert meeting method was used to divide pediatric medicines into five categories: child-specific medicine (CSM), co-use medicine for adults and children (CMAC), other pediatric medicines (OCM), off-label medicine use (OMU), and non-child medicine (NM).Results: A total of 60 hospitals nationwide participated in this survey, namely, 20 children’s hospitals (C-hosp), 14 maternal and child healthcare hospitals (MCHC-hosp), and 26 general hospitals (G-hosp). The average number of drug catalogs in G-hosp was significantly higher than that in C-hosp and MCHC-hosp. CSM accounted for 9.77% of the C-hosp catalog, 7.12% of the MCHC-hosp catalog, and 1% of the G-hosp catalog. The availability rate of CMAC was 49.63% in C-hosp and 40.87% and 31% in MCHC-hosp and G-hosp, respectively. The proportion of OCM in C-hosp (27.28%) was higher than that in MCHC-hosp (13.4%) and G-hosp (5%). The OMU occupied ratio in C-hosp, MCHC-hosp, and G-hosp is not negligible, which was 12.06%, 8.7%, and 10% respectively. The proportion of NM in C-hosp was almost negligible but was 29.91% and 53% in MCHC-hosp and G-hosp, respectively. Compared to the CSM and CMAC listed in China, the share of CSM in C-hosp was close to 40%, which was much higher than that of G-hosp and MCHC-hosp. In contrast, the share of CMAC in G-hosp was nearly 30%, which was significantly higher than that in C-hosp and MCHC-hosp. Health insurance covers most of these five types of pediatric medicines, with the proportion of insured medicines reaching close to 80% in C-hosp and approximately 85% in MCHC-hosp and G-hosp.Discussion: The availability of specific medicines suitable for use in children is generally low, and even CSM in specialized hospitals such as C-hosp cannot meet the relatively high accessibility level of WHO evaluation standards. Policies and measures should be implemented to boost the research and development of pediatric medicines, as well as supplement safety information lacking in instruction manuals.

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Section: Introductionmentioning

confidence: 99%

Real-world data for the availability of pediatric medicines in Chinese hospitals: a multi-center survey and analysis

Ruan,

Chen,

Cai

et al. 2024

Front. Pharmacol.

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Medicine use in children aged under 12 years—Population survey in Finland

Kesti

Saastamoinen

Lavikainen

et al. 2022

Pharmacoepidemiology and Drug

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Purpose: To study the prevalence of prescribed and over-the-counter (OTC) medicine use in children under 12 years of age in Finland and to examine factors associated with the medicine use. Methods: A nationwide population survey was carried out in Finland in spring 2018 with a random sample of children under 12 years (n = 8000). A response rate of 24% (n = 1921) was attained. The questionnaire was sent to the child's primary guardian. Current use of prescribed medicines and the use of OTC medicines in the preceding 2 days were the main outcome measures. Results: Of all the children 19% had used prescribed medicines, 15% OTC medicines, and 31% either prescription or OTC medicines during the preceding 22 days. Children's health related factors were positively associated with prescribed medicine use including fairly good to poor health status, symptoms experienced, and illnesses diagnosed by a physician. The guardian's healthcare education and use of prescribed medicines were also associated with children's prescribed medicine use. Symptoms of illnesses and fairly good health status were found to be associated with childrens' use of OTC medicines. Conclusions: The use of medicines in children under 12 years of age is quite common in Finland. As expected, children's health-related factors were associated with medicine use. Also, guardians' healthcare education and the use of prescribed medicines were associated with children's prescription medicine use. Children's medicine use should be continuously monitored and investigated further to identify the reasons leading to appropriate and inappropriate medicine use in children. K E Y W O R D S child, medicine use, over-the-counter medicines, prescribed medicines, survey Key Points • One in five children under 12 years in Finland used prescribed medicines and one in seven over-the-counter (OTC) medicines.

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Changes in the list of over-the-counter drugs containing biologically active substances of plant origin which are intended to be applied among pediatric patients in Bulgaria

Hadzhieva,

Mihaylova,

Dimitrov

et al. 2024

PHAR

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Over-The-Counter (OTC) drugs constitute a large category found in pharmacies. They are intended to be applied among adult patients and infants as well. They are also used for prophylaxis. The number of OTC drugs containing biologically active substances (BAS) of plant origin which are intended to be applied among children is insignificant. The changes in the list of OTC medicines which are applied among children mainly affect products influencing cold and flu symptoms. These medicines often contain decongestants which are considered to be the main reason for the emergence of a number of unwanted drug reactions. In addition, the list of OTC drugs has been supplemented with new medicines, most of which contain the same BAS of plant origin, but the product has been produced by a different manufacturer.

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Medicine use in children aged under 12 years—Population survey in Finland

Cited by 4 publications

References 32 publications

Real-world data for the availability of pediatric medicines in Chinese hospitals: a multi-center survey and analysis

Real-world data for the availability of pediatric medicines in Chinese hospitals: a multi-center survey and analysis

Medicine use in children aged under 12 years—Population survey in Finland

Changes in the list of over-the-counter drugs containing biologically active substances of plant origin which are intended to be applied among pediatric patients in Bulgaria

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