2019
DOI: 10.26650/istanbuljpharm.2019.18008
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Medicinal plants with reported anxiolytic and sedative activities in Nigeria: A systematic review

Abstract: Medicinal plants have been widely used in folklore medicine in the treatment of various diseases such as mental and neurological disorders. Mental disorders like anxiety and depression are very common among Nigerian populace. The purpose of this review was to access and evaluate several articles published on the anxiolytic and sedative properties of medicinal plants in Nigeria and to find out the gaps left for further research and drug development. Eighty-two publications available among Nigerian Universities … Show more

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Cited by 9 publications
(5 citation statements)
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“…The fruits possess molluscidal and antifungal activities [41,42]. The root possesses sedative and tranquilizing activity [10,23], while the essential oils expressed have been seen to possess antipsychotic, antimicrobial, and antifungal activities [26,45,46,47].…”
Section: Discussionmentioning
confidence: 99%
“…The fruits possess molluscidal and antifungal activities [41,42]. The root possesses sedative and tranquilizing activity [10,23], while the essential oils expressed have been seen to possess antipsychotic, antimicrobial, and antifungal activities [26,45,46,47].…”
Section: Discussionmentioning
confidence: 99%
“…The sedative activity of the oil was observed during the median lethal dose determination. Some agents with sedative property like benzodiazepines, barbiturates, and also some researched medicinal plants have been found to elicit an anxiolytic activity at lower doses (Abubakar and Haque, 2019). Hence, EOAO was subjected to anxiolytic activity test at lower doses (6.25 mg/kg i.p., 12.5 mg/kg i.p., and 25 mg/kg i.p.)…”
Section: Discussionmentioning
confidence: 99%
“…In treatment, Diazepam (25 mg/Kg, i. p.) was administered to all groups. Each animal was observed for the duration of sleep and the readings were recorded as the time interval between the loss and regaining of righting reflex 17 .…”
Section: Diazepam-induced Sleeping Timementioning
confidence: 99%