Medicinal Plant Extracts

Vicaş, Laura; Mureşan, Mariana

doi:10.3390/plants10050838

Cited by 5 publications

(3 citation statements)

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“…The extraction yield for the analysed extract was 21%. Total polyphenols content (TPC) TPC was determined using Folin-Ciocâlteu method described in literature [59], a widely used colorimetric method, and the total polyphenols content was calculated as gallic acid equivalents/100 g dry vegetable product (mg equivalent of gallic acid (GAE)/100 g dry weight (DW)).…”

Section: Preparation Of the Extractmentioning

confidence: 99%

Phytochemical Screening and Biological Activity of Ethanolic Extract of Rosa X Damascena Mill. Cultivated in the Western Region of Romania

Gavra¹

2022

FARMACIA

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Rosa x damascena Mill. has pharmacological properties that are partially attributed to their abundance in phenolic compounds. We investigated the alcoholic extract from the plants petals. Microscopic examination of Rosa x damascena Mill. petals showed that both of the adaxial and abaxial epidermal cells contained pigments. The antimicrobial activity of the extract was determined by the disc diffusion method. The most sensitive antimicrobial effect was on the strain Pseudomonas aeruginosa. The SOD-like activity of Rosa damascena alcoholic extract has been tested both in vitro and in vivo. Three cell lines were used for determining the cytotoxicity of Rosa damascena alcoholic extract, a human cervical carcinoma line (HeLa), a human radical growth phase melanoma cell line (WM35) and a normal fibroblastic epithelial cell line (HFL1) by MTT method. The Rosa damascena extract presents SOD-like activity and is cytotoxic on HeLa and WM35 cell lines. Due to these results, Rosa x damascena extracts can be used for their bioactive potential. RezumatRosa x damascena Mill. are proprietăți farmacologice care sunt parțial atribuite abundenței lor în compuși fenolici. Am investigat extractul alcoolic din petalele acestei plante. Examinarea microscopică a petalelor a arătat că ambele celule epidermice adaxiale și abaxiale conțin pigmenți. Activitatea antimicrobiană a extractului a fost determinată prin metoda de difuzie a discului. Cel mai sensibil efect antimicrobian a fost asupra tulpinii Pseudomonas aeruginosa. Activitatea SOD a extractului alcoolic din Rosa damascena a fost testată atât in vitro, cât și in vivo. Au fost utilizate trei linii celulare pentru determinarea citotoxicității extractului alcoolic, o linie de carcinom cervical uman (HeLa), o linie celulară de melanom în fază de creștere radicală umană (WM35) și o linie celulară epitelială fibroblastică normală (HFL1) prin metoda MTT. Extractul de Rosa damascena prezintă activitate asemănătoare SOD și este citotoxic pe liniile celulare HeLa și WM35. Datorită acestor rezultate, extractele de Rosa x damascena pot fi utilizate pentru potențialul lor bioactiv.

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Section: Preparation Of the Extractmentioning

confidence: 99%

Phytochemical Screening and Biological Activity of Ethanolic Extract of Rosa X Damascena Mill. Cultivated in the Western Region of Romania

Gavra¹

2022

FARMACIA

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“…21,25,26 The major obstacle in phytochemical analysis is a choice of proper extraction methods and highly efficient solvents due to the lack of standardisation of methods for extraction of phenolic compounds from plants. [27][28][29][30][31][32][33] Since the applied extraction conditions vary widely in the literature, the experimental plan was used in this work to determine the optimal conditions for effective extraction of flavonoids from the leaf of I. sibirica L.…”

Section: Introductionmentioning

confidence: 99%

Development of approach for flavonoid profiling of biotechnological raw materials Iris sibirica L. by HPLC with high‐resolution tandem mass spectrometry

Karpitskiy

Бессонова

Карцова

et al. 2022

Phytochemical Analysis

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Introduction Iris L. are promising in medicine due to the biological activity of extracts. Iris sibirica L. is spread in Russia but its phytochemical composition has not been studied in detail though it is included in the Red Book. For this reason, I. sibirica L. biotechnology is in high demand. One of the key points in biotechnology is the regulation of plant metabolism using phytohormones. Obtaining of chromatographic metabolite profiles allows to control this process. Objective The aim of this study was to develop an approach for effective control of biotechnological raw materials of I. sibirica L. by flavonoid profiles using high‐performance liquid chromatography–tandem mass spectrometry (HPLC–MS/MS) and to investigate the influence of phytohormones in nutrient media on content of flavonoids. Methodology Iris sibirica L. regenerated plants were grown on Murashige–Skoog media with 6‐benzylaminopurine (6‐BAP) and α‐naphtylacetic acid (NAA) additives. To optimise extraction conditions, the design of the experiment was used. Profiles of polyphenols were obtained by HPLC–MS/MS in the positive and negative ionisation modes. Results The process for efficient extraction from leaves of I. sibirica L. were developed. The factors influencing the extraction efficiency of flavonoids have been determined. A total of 36 compounds were identified by HPLC–MS/MS. Among them isoflavones and their glycosides are the main classes. Addition of an auxin‐like hormone increased the non‐polar flavonoid levels, but decreased the polar ones. The variation in concentration of cytokinin (6‐BAP) affected almost all of the analytes. Conclusion The methodology for effective control of I. sibirica L. raw plant material biotechnology was developed by analysing obtained chromatographic polyphenol profiles.

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“…Estima-se que há diversos extratos vegetais com propriedades medicinais (VICAȘ;MUREȘAN, 2021). Há evidências científicas que relatam atividade antimicrobiana(GONELIMALI et al, 2018).…”

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Fertilidade Em Pacientes Com Trauma Raquimedular Prévio

Roza¹,

Oliveira²,

Lopes³

2022

Epidemiologia, Diagnóstico E Intervenção Em Saúde Pública

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PÚBLICA" através de pesquisas científicas aborda em seus 17 capítulos o conhecimento multidisciplinar que compõe essa grande área da saúde pública em diversas modalidades.Almeja-se que a leitura deste e-book possa incentivar o desenvolvimento de estratégias de atuação coletiva e educacional.A Saúde, enquanto estado vital, setor de produção e campo do saber, está articulada à estrutura da sociedade através das suas instâncias econômica e político-ideológica, possuindo, portanto, uma historicidade. As ações de saúde (promoção, proteção, recuperação, reabilitação) constituem uma prática social e trazem consigo as influências do relacionamento dos grupos sociais. Na América Latina, e no Brasil em particular, realiza-se nas duas últimas décadas um trabalho de construção de novas teorias, enfoques e métodos da epidemiologia e da planificação em saúde, além de investigações concretas buscando a aplicação de métodos das ciências sociais no campo da saúde coletiva. Desse esforço de reconstrução teórica, tem emergido no campo novos objetos de conhecimento e de intervenção, como por exemplo os casos da comunicação social em saúde e da vigilância em saúde. Nesse aspecto, cabe referir o desenvolvimento científico e tecnológico do campo mediante importantes contribuições nas

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Medicinal Plant Extracts

Abstract: The therapeutic benefits of medicinal plants are well known and have been collected as important data on ethnomedicine [...]

Cited by 5 publications

References 10 publications

Phytochemical Screening and Biological Activity of Ethanolic Extract of Rosa X Damascena Mill. Cultivated in the Western Region of Romania

Phytochemical Screening and Biological Activity of Ethanolic Extract of Rosa X Damascena Mill. Cultivated in the Western Region of Romania

Development of approach for flavonoid profiling of biotechnological raw materials Iris sibirica L. by HPLC with high‐resolution tandem mass spectrometry

Fertilidade Em Pacientes Com Trauma Raquimedular Prévio

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