Medicinal Fungi with Antiviral Effect

Zhang, Yu; Zhang, Guoying; Ling, Jianya

doi:10.3390/molecules27144457

Cited by 25 publications

(12 citation statements)

References 143 publications

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“…The results showed that among the twenty-two edible mushroom proteins, the precious edible mushroom proteins were more common edible mushrooms and had higher immune activity. It was shown that medicinal fungi have a stronger immunomodulatory ability, and since CMP, CVP, IOP, TAP, MEP, and OSP are all valuable edible fungi, the reason for the stronger immunomodulatory effect of precious edible fungal proteins may be that medicinal fungi have some special proteins that are not found in common edible fungi ( 56 ).…”

Section: Discussionmentioning

confidence: 99%

Immune regulatory functions of biologically active proteins from edible fungi

et al. 2023

Front. Immunol.

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Proteins from edible mushrooms have a variety of biological activities. Here, thirteen precious edible mushrooms such as Ophiocordyceps sinensis, Ganoderma lucidum, and Morchella esculenta and nine common edible mushrooms such as Flammulina velutipes, Pleurotus ostreatus, and Pleurotus eryngii, etc., from which their proteins were extracted, their composition analyzed and their immunomodulatory activity assessed. Rare mushrooms are a species of edible mushrooms with higher edible value and medicinal value than common edible mushrooms. The results showed that all the different edible mushroom crude proteins increased the proliferation and phagocytosis of mouse macrophages, and we found that these edible mushroom proteins affected the secretion of reactive oxygen species and nitric oxide by mouse macrophages. Further studies on cytokines secreted by mouse macrophages showed a significant increase in pro-inflammatory cytokines, suggesting that edible mushroom proteins promote the polarisation of macrophages into classical M1-type macrophages, further demonstrating that edible mushroom proteins enhance immunity. It was also found that the immunomodulatory activity of the precious edible mushroom proteins was significantly higher than that of the common edible mushroom proteins. These results have important implications for the processing and product development of edible mushroom proteins.

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Section: Discussionmentioning

confidence: 99%

Immune regulatory functions of biologically active proteins from edible fungi

et al. 2023

Front. Immunol.

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“…A serial of 80 natural compounds isolated from Ganodermaceae [ [10] , [11] , [12] , [13] , [14] , [15] , [16] ] was assembled for the molecular docking process, sourced from the database available at http://phytochem.nal.usda.gov ( Supporting information Table S1 ). The 3D structures of these compounds were retrieved from PubChem ( http://pubchem.ncbi.nlm.nih.gov ) and prepared using MarvinSketch (ChemAxon, Cambridge, MA, USA).…”

Section: Methodsmentioning

confidence: 99%

Anti-Staphylococcus aureus potential of compounds from Ganoderma sp.: A comprehensive molecular docking and simulation approaches

Nguyen,

Nguyen

et al. 2024

Heliyon

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“…Although a mineral deficiency is rare, some mushrooms are a rich source of specific minerals (e.g., selenium, magnesium, and zinc), which may play a direct or indirect role in their anti-influenza properties, performing a crucial role in boosting the immune system and preventing the viral infections, and preserving the homeostasis process in the human body ( 128 ). Dried mushrooms might be a source of mineral components indispensable for human health ( 129 ).…”

Section: Antiviral Properties Of Mushroomsmentioning

confidence: 99%

Mushrooms as future generation healthy foods

Bell

Silva

Guina³

et al. 2022

Front. Nutr.

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The potential of edible mushrooms as an unexploited treasure trove, although rarely included in known food guidelines, is highlighted. Their role in shielding people against the side effects of an unhealthy stylish diet is reviewed. Mushrooms complement the human diet with various bioactive molecules not identified or deficient in foodstuffs of plant and animal sources, being considered a functional food for the prevention of several human diseases. Mushrooms have been widely used as medicinal products for more than 2,000 years, but globally the potential field of use of wild mushrooms has been untapped. There is a broad range of edible mushrooms which remain poorly identified or even unreported which is a valuable pool as sources of bioactive compounds for biopharma utilization and new dietary supplements. Some unique elements of mushrooms and their role in preventative healthcare are emphasized, through their positive impact on the immune system. The potential of mushrooms as antiviral, anti-inflammatory, anti-neoplastic, and other health concerns is discussed. Mushrooms incorporate top sources of non-digestible oligosaccharides, and ergothioneine, which humans are unable to synthesize, the later a unique antioxidant, cytoprotective, and anti-inflammatory element, with therapeutic potential, approved by world food agencies. The prebiotic activity of mushrooms beneficially affects gut homeostasis performance and the balance of gut microbiota is enhanced. Several recent studies on neurological impact and contribution to the growth of nerve and brain cells are mentioned. Indeed, mushrooms as functional foods' nutraceuticals are presently regarded as next-generation foods, supporting health and wellness, and are promising prophylactic or therapeutic agents.

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Medicinal Fungi with Antiviral Effect

Cited by 25 publications

References 143 publications

Immune regulatory functions of biologically active proteins from edible fungi

Immune regulatory functions of biologically active proteins from edible fungi

Anti-Staphylococcus aureus potential of compounds from Ganoderma sp.: A comprehensive molecular docking and simulation approaches

Mushrooms as future generation healthy foods

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