Medicinal Flowers. XXXVI.¹⁾ Acylated Oleanane-Type Triterpene Saponins with Inhibitory Effects on Melanogenesis from the Flower Buds of Chinese <i>Camellia japonica</i>

Abstract

Four acylated oleanane-type triterpene oligoglycosides, sanchakasaponins E-H, were isolated from the flower buds of Camellia japonica cultivated in Yunnan province, China, together with four known triterpene oligoglycosides. The chemical structures of the new triterpene oligoglycosides were elucidated on the basis of chemical and physicochemical evidence. The inhibitory effects of the triterpene oligoglycoside constituents on melanogenesis in theophylline-stimulated B16 melanoma 4A5 cells were investigated.

Medicinal Flowers. XXXX.¹⁾ Structures of Dihydroisocoumarin Glycosides and Inhibitory Effects on Aldose Reducatase from the Flowers of <i>Hydrangea macrophylla</i> var. <i>thunbergii</i>

“…[2][3][4][5][6] However, a full chemical analysis of the flowers from this plant has not yet been performed. In the course of our chemical and pharmacological studies on Hydrangea plants [2][3][4][5][6][7][8] and medicinal flowers, [9][10][11][12][13][14] we recently reported the isolation and structure elucidation of secoiridoid glycosides named hydrangeamines A and B with a pyridine ring from the flowers of H. macrophylla var. thunbergii cultivated in Nagano prefecture, Japan.…”

Medicinal Flowers. XXXVIII. Structures of Acylated Sucroses and Inhibitory Effects of Constituents on Aldose Reducatase from the Flower Buds of Prunus mume

“…The alkaline hydrolysis of 2 and 3 yielded sucrose, whereas the acid hydrolysis of 2 and 3 yielded d-glucose and fructose together with (E)-p-coumaric acid. 28 3 CO-×6) for 5], respectively, together with a (E)-p-coumaroyl group and a sucrose moiety. The positions of acetyl groups of 4 and 5 were confirmed based on HMBC spectroscopy.…”

“…In the course of our studies on bioactive constituents from medicinal flower, [2][3][4][5][6] we previously reported the isolation and structure elucidation of acylated sucroses named prunoses I (11), II (12), and III (13) with inhibitory effects on platelet aggregation and aldose reductase and radical scavenging effect from the flower buds of Prunus (P.) mume Sieb. et Zucc.…”

“…1) As a continuing study, five new acylated sucroses termed mumeoses F (1), G (2), H (3), I (4), and J (5) were isolated from the flower buds of Chinese Prunus mume together with 29 known compounds including acylated quinic acid analogs. This paper deals with the structure elucidation of new acylated sucroses (1)(2)(3)(4)(5) and the inhibitory effects of principle constituents on aldose reductase.…”

Separation of nine novel triterpene saponins from Camellia japonica seeds using high‐performance countercurrent chromatography and reversed‐phase high‐performance liquid chromatography

“…Camellia japonica L. (Theaceae) is an evergreen shrub and one of the best‐known species of the genus Camellia along with tea tree ( C. sinensis ). In Asian countries, including Korea, China, and Japan, C. japonica is cultivated as a popular ornamental tree and its seeds are a good source of cooking oil, and used in cosmetics and traditional medicine …”