Medication Reconciliation Effect on Prolonged Inpatient Stress Ulcer Prophylaxis

Zeigler, Amy J; McAllen, Karen; Slot, Martha G.; Barletta, Jeffrey F.

doi:10.1345/aph.1l123

Cited by 24 publications

(65 citation statements)

References 19 publications

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“…In none of the studies was the allocation sequence randomly assigned and the allocation concealed. Six studies did not report similar baseline characteristics [ 40 , 42 , 43 , 48 – 50 ], eight studies did not perform a sample size calculation [ 40 – 42 , 44 , 45 , 48 – 50 ], and nine studies had no plan for handling missing data [ 40 , 42 – 46 , 48 – 50 ].…”

Section: Resultsmentioning

confidence: 99%

Improving clinical handover between intensive care unit and general ward professionals at intensive care unit discharge

Sluisveld¹,

Hesselink²,

Hoeven

et al. 2015

Intensive Care Med

102

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PurposeTo systematically review and evaluate the effectiveness of interventions in order to improve the safety and efficiency of patient handover between intensive care unit (ICU) and general ward healthcare professionals at ICU discharge.MethodsPubMed, CINAHL, PsycINFO, EMBASE, Web of Science, and the Cochrane Library were searched for intervention studies with the aim to improve clinical handover between ICU and general ward healthcare professionals that had been published up to and including June 2013. The methods for article inclusion and data analysis were pre-specified and aligned with recommendations outlined in the PRISMA guideline. Two reviewers independently extracted data (study purpose, setting, population, method of sampling, sample size, intervention characteristics, outcome, and implementation activities) and assessed the quality of the included studies.ResultsFrom the 6,591 citations initially extracted from the six databases, we included 11 studies in this review. Of these, six (55 %) reported statistically significant effects. Effective interventions included liaison nurses to improve communication and coordination of care and forms to facilitate timely, complete and accurate handover information. Effective interventions resulted in improved continuity of care (e.g., reduced discharge delay) and in reduced adverse events. Inconsistent effects were observed for use of care, namely, reduction of length of stay versus increase of readmissions to higher care. No statistically significant effects were found in the reduction of mortality. The overall methodological quality of the 11 studies reviewed was relatively low, with an average score of 4.5 out of 11 points.ConclusionsThis review shows that liaison nurses and handover forms are promising interventions to improve the quality of patient handover between the ICU and general ward. More robust evidence is needed on the effectiveness of interventions aiming to improve ICU handover and supportive implementation strategies.Electronic supplementary materialThe online version of this article (doi:10.1007/s00134-015-3666-8) contains supplementary material, which is available to authorized users.

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Section: Resultsmentioning

confidence: 99%

Improving clinical handover between intensive care unit and general ward professionals at intensive care unit discharge

Sluisveld¹,

Hesselink²,

Hoeven

et al. 2015

Intensive Care Med

102

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“…Other studies showed the positive impact of pharmacists in improving clinical and cost outcomes in hospitalized patients receiving PPI by either switching patients to a less expensive agent or discontinuing the medication for unnecessary indication. Type of interventions included direct collaboration with physicians, guidelines implementation, or pharmacist-led medication reconciliation [8][9][10].…”

Section: Discussionmentioning

confidence: 99%

Cost reduction associated with restriction policy on dispensing intravenous esomeprazole in lebanon

2010

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“…3 Second, there is the belief that the risk for an adverse event is low given the short time therapy is administered, but many patients get discharged to home on stress ulcer prophylaxis. 4 Consequently, inadvertent long-term use could lead to adverse events (see the accompanying article by Abrahamsen et al 5 ) and added cost. Finally, there is the misbelief of what truly constitutes "risk" for stressrelated clinically significant bleeding.…”

Section: Acid Suppressive Therapy In Noncritically Ill Patientsmentioning

confidence: 99%

QRS Morphology Rather Than QRS Duration for Predicting CRT Response

Selzman¹

2011

Arch Intern Med

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with dementia, 7 but the association found in our study remained after controlling for them, thus implicating other explanations for the gradient seen. One possibility is a toxic effect of hypercortisolemia in depression on the hippocampus. 8 Further research is required to investigate whether appropriate treatment of depression reduces dementia risk. 1. Prince M, Patel V, Saxena S, et al. No health without mental health. Lancet. 2007;370(9590):859-877. 2. Kessing LV, Nilsson FM. Increased risk of developing dementia in patients with major affective disorders compared to patients with other medical illnesses. J Affect Disord. 2003;73(3):261-269. 3. Lindsay J, Laurin D, Verreault R, et al. Risk factors for Alzheimer's disease: a prospective analysis from the Canadian Study of Health and Aging. Am J Epidemiol. 2002;156(5):445-453. 4. Colhoun H, Dong W, Prescott-Clarke P. Health Survey for England: Survey Methodology and Documentation. Vol 2. London, England: HMSO; 1994. 5. Holi MM, Marttunen M, Aalberg V. Comparison of the GHQ-36, the GHQ-12 and the SCL-90 as psychiatric screening instruments in the Finnish population. Nord J Psychiatry. 2003;57(3):233-238. 6. Employment Department Group/Office of Population Censuses and Surveys. Standard Occupational Classification. London, England: HMSO; 1990. 7. Whitmer RA, Sidney S, Selby J, Johnston SC, Yaffe K. Midlife cardiovascular risk factors and risk of dementia in late life. Neurology. 2005;64(2):277-281. 8. Brown ES, Varghese FP, McEwen BS. Association of depression with medical illness: does cortisol play a role?

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Medication Reconciliation Effect on Prolonged Inpatient Stress Ulcer Prophylaxis

Abstract: The strategy of MR alone will not decrease the incidence of prolonged SUP in hospitalized patients. Other techniques should be evaluated to encourage appropriate use of acid-suppressive agents.

Cited by 24 publications

References 19 publications

Improving clinical handover between intensive care unit and general ward professionals at intensive care unit discharge

Improving clinical handover between intensive care unit and general ward professionals at intensive care unit discharge

Cost reduction associated with restriction policy on dispensing intravenous esomeprazole in lebanon

QRS Morphology Rather Than QRS Duration for Predicting CRT Response

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