Medical significance and management of staphylococcal biofilm

Agarwal, Ankur; Singh, Kamleshwar; Jain, Amita

doi:10.1111/j.1574-695x.2009.00601.x

Cited by 77 publications

(55 citation statements)

References 134 publications

(150 reference statements)

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“…Prosthetic valve infection causes tissue damage facilitating the accumulation of platelets, fibrinogen, fibronectin and plasma proteins at the valve prostheses, sutures, and mechanical and inflammatory lesion sites. Staphylococci, particularly, S. aureus and S. epidermidis, owing to their biofilm forming ability, were the most identified species in prosthetic valves [71,72] while Enterococci were seen in late forms of PVE. The bacterial growth leads to separation between valve and tissue resulting in paravalvular leakage [72,73].…”

Section: Infective Endocarditis (Ie)mentioning

confidence: 99%

“…Staphylococci, particularly, S. aureus and S. epidermidis, owing to their biofilm forming ability, were the most identified species in prosthetic valves [71,72] while Enterococci were seen in late forms of PVE. The bacterial growth leads to separation between valve and tissue resulting in paravalvular leakage [72,73]. Peripheral venous catheter (PVC) infections [74] and central venous catheter (CVC) infections [75] mostly result in IE.…”

Section: Infective Endocarditis (Ie)mentioning

confidence: 99%

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Clinical Implications of Circulating Microbiome in Cardiovascular Disease Patients

2017

JCCR

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The circulating microbiome or the blood microbiome has been analysed recently in chronic inflammatory diseases like obesity, diabetes, cirrhosis and cardiovascular diseases (CVDs) in humans. Evidences that microbial components in blood could play a crucial role in the pathophysiological events leading to or during the course of disease continue to mount. The blood microbiome has been investigated primarily by profiling the circulating bacterial and viral elements using high-throughput sequencing technologies. However, the clinical implications of circulating microbiome in humans remain largely unexplored. The evidence for the presence of a stable blood microbiome in CVDs is still questionable. Nevertheless, there is evidence for a link between the circulating microbiome in obesity, diabetes and CVDs, indicating the influence of physiological, biochemical and environmental factors on the circulating microbiome in metabolic diseases. With this background, we explore the reports on the clinical consequences of bacteremia in CVD patients which formed the basis for the analyses on the topic "circulating microbiome".

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Section: Infective Endocarditis (Ie)mentioning

confidence: 99%

Section: Infective Endocarditis (Ie)mentioning

confidence: 99%

Clinical Implications of Circulating Microbiome in Cardiovascular Disease Patients

2017

JCCR

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“…The initial adhesion is based on attraction and repulsion forces between the cells and the surface. These forces include electrostatic and hydrophobic interactions, Van der Waals forces and hydrodynamic forces, in adequate temperatures (Agarwal et al, 2010). After the adhesion to the surface, the bacteria grow and divide, forming dense agglomerates which are characteristic of biofilm.…”

Section: Mechanisms Of Biofilm Formationmentioning

confidence: 99%

Antibiofilm activity of natural substances derived from plants

Nogueira¹,

Costa²,

Cunha³

et al. 2017

Afr. J. Microbiol. Res.

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The main objective of this study was to conduct a review of bioactive substances derived from plants which show antimicrobial/antibiofilm properties. Vegetable species were widely employed as ingredients in medicine based on traditional knowledge. Various secondary metabolites have been proven to inhibit bacterial growth. Bacterial resistance mechanisms have increased over the years. Biofilms are types of bacterial association which gives the communities a higher resistance to drugs. The formation process of biofilms, the problems caused by them and the natural substances, as well as their main chemical components and action mechanisms, have been described according to existing literature.

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“…Staphylococcus aureus and Staphylococcus epidermidis are pathogens able to produce biofilm on various materials and surfaces used in the biomedical, food, and industrial fields (2)(3)(4). Staphylococcal biofilm formation is a dynamic process that involves different mechanisms (5,6). The initial adhesion phase is largely governed by physicochemical interactions between the bacteria and substrate and by environmental factors such as pH and temperature (7)(8)(9)(10).…”

mentioning

confidence: 99%

Staphylococcal biofilm formation as affected by type acidulant

Nostro

Cellini

Ginestra

et al. 2013

APMIS

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Staphylococcal growth and biofilm formation in culture medium where pH was lowered with weak organic (acetic and lactic) or strong inorganic (hydrochloric) acids were studied. The effects were evaluated by biomass measurements, cell-surface hydrophobicity, scanning electron microscopy (SEM), and confocal laser scanning microscopy (CLSM). The results demonstrated that the inhibition was related to type of acidulant and pH value. At pH 5.0, the antibacterial effect was more pronounced in the presence of acetic acid (58-60% growth reduction) compared with that in the presence of lactic (7-16% growth reduction) and hydrochloric acids (23-24% reduction). The biofilm biomass of Staphylococcus aureus and Staphylococcus epidermidis was reduced by 92, 85, 63, and 93, 87, 81% after exposition to acetic, lactic, and hydrochloric acids, respectively. Increasing the pH from 5.0 to 6.0 resulted in a noticeable reduction in the effectiveness of acids. A minor cells hydrophobic character was also documented. The SEM and CLSM revealed a poorly structured and thinner biofilm compared with the dense and multilayered control. Acidic environment could have important implications for food-processing system to prevent bacterial colonization and control biofilm formation. The findings of this study lead to consider the rational use of the type of acid to achieve acidic environments.

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Medical significance and management of staphylococcal biofilm

Cited by 77 publications

References 134 publications

Clinical Implications of Circulating Microbiome in Cardiovascular Disease Patients

Clinical Implications of Circulating Microbiome in Cardiovascular Disease Patients

Antibiofilm activity of natural substances derived from plants

Staphylococcal biofilm formation as affected by type acidulant

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