2016
DOI: 10.1016/j.disamonth.2016.05.014
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Medical marijuana and pain management

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Cited by 20 publications
(9 citation statements)
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“…The CB 2 receptors, localized outside of the central nervous system, have also been implicated in pain management. 17, 31 Importantly, other cannabinoids besides THC also contribute to the nociceptive properties of MC. 15 …”
Section: Introductionmentioning
confidence: 99%
“…The CB 2 receptors, localized outside of the central nervous system, have also been implicated in pain management. 17, 31 Importantly, other cannabinoids besides THC also contribute to the nociceptive properties of MC. 15 …”
Section: Introductionmentioning
confidence: 99%
“…Even some not-soridiculous thoughts and ideas can produce a giggle response, because marijuana magnifies the response to positive information. However, in some cases, such as a person taking marijuana quietly, it has a calming effect and can sometimes relieve pain (6). Therefore, the effect of marijuana is closely related to the environment, mainly because it affects the perception function of the brain.…”
Section: Short-term Effects Of Marijuana Emotional Cognitive Distortionmentioning
confidence: 99%
“…The most commonly used cannabinoids are delta-9-tetrahydrocannabinol (THC) and Cannabidiol (CBD). THC consists of psychoactive properties and is the most abundant cannabinoid found within the cannabis plant, whereas CBD is minimally psychoactive and the second most abundant [1].Both THC and CBD have specific actions within the Endocannabinoid System (ECS) at the Cannabinoid type 1 (CB1) and cannabinoid type 2 (CB2) receptors, which were discovered 30 years ago [2,4,5]. The ECS is a complex system of receptors, ligands, and enzymes, which aid in the regulation of fundamental processes at the level of the central andperipheral nervous systems [6].…”
Section: Introductionmentioning
confidence: 99%
“…Cannabinoid type 1 and cannabinoid type 2 receptors are involved in the immune and nervous system process, such as inflammation, neural development and pain [2]. Cannabinoid and opioid receptors are believed to have an influence on the spinal level modulation of peripheral pain inputs [5].…”
Section: Introductionmentioning
confidence: 99%