Medical control of intraocular pressure after phacoemulsification

Dayanir, Volkan; Özcura, Fatin; Kır, Erkin; Topaloğlu, Aziz; Özkan, Seyhan B.; Aktunç, Turgay

doi:10.1016/j.jcrs.2004.07.024

Cited by 42 publications

(37 citation statements)

References 15 publications

(9 reference statements)

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“…[20][21][22][23] In our study, the effectiveness of dorzolamide-timolol maleate combination was not different from that of oral acetazolamide.…”

Section: Discussioncontrasting

confidence: 40%

“…There was no statistically significant difference between two groups (p=0.924). The mean postoperative IOP (1 st day) of the first group was 15.27±2.90 (SD) (11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23) mmHg and that of the second group was 14.82±2.57 (SD) (11-23) mmHg. There was no statistically significant difference between two groups (p=0.505).…”

Section: Resultsmentioning

confidence: 97%

“…and that of the second group was 14.67±2.77 (SD) (11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21) mmHg (p=0.924). The mean postoperative IOP(1 st day) of the first group was 15.27±2.90 (SD) (11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23) mmHg and that of the second group was 14.82±2.57 (SD) (11-23) mmHg (p=0.505). The mean postoperative IOP (1 st week) of the first group was 13.72±2.44 (SD) (10-18) mmHg and that of the second group was 13.64±2.53 (SD) (10)(11)(12)(13)(14)(15)(16)(17)(18)(19) mmHg (p=0.895).…”

Section: Comparison Of Efficacy and Safety Of Topical Dorzolamide-timmentioning

confidence: 95%

See 2 more Smart Citations

Comparison of Efficacy and Safety of Topical Dorzolamide-Timolol Maleate Combination with Oral Acetazolamide for Prevention of Intraocular Pressure Rise Following Phacoemulsification Surgery

Çetinkaya¹,

Akçam²,

Gürdağ³

et al. 2015

Turkiye Klinikleri J Ophthalmol

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A AB BS S T TR RA AC CT T O Ob bj je ec ct ti iv ve e: : To compare the efficacy and safety of topical dorzolamide-timolol maleate combination with oral acetazolamide for prevention of intraocular pressure rise following phacoemulsification surgery. M Ma at te er ri ia al l a an nd d M Me et th ho od ds s: : Sixty-seven eyes of 67 patients with cataracts (33 males, 34 females) who had undergone phacoemulsification and intraocular lens implantation surgery were evaluated retrospectively. Patients were divided into two groups. Group 1 comprised 33 (49%) patients who received oral acetazolamide 250 mg (Diazomid 250 mg tb) 1 hour before the surgery and 1hour after surgery and 125 mg 3 times a day for 3 days following surgery. Group 2 comprised 34 (51%) patients who received topical dorzolamidetimolol maleate combination 1 drop 1 hour before the surgery and twice a day for 3 days following surgery. R Re es su ul lt ts s: : The mean preoperative intraocular pressure (IOP) of the first group was 14.60±3.21 standard deviation (SD) (range 10-21) mmHg. and that of the second group was 14.67±2.77 (SD) (11-21) mmHg (p=0.924). The mean postoperative IOP(1 st day) of the first group was 15.27±2.90 (SD) (11-23) mmHg and that of the second group was 14.82±2.57 (SD) (11-23) mmHg (p=0.505). The mean postoperative IOP (1 st week) of the first group was 13.72±2.44 (SD) (10-18) mmHg and that of the second group was 13.64±2.53 (SD) (10-19) mmHg (p=0.895). C Co on nc cl lu us si io on n: : For prophylaxis of postoperative IOP rise after an uneventful cataract surgery, topical-dorzolamid timolol maleate combination and oral acetazolamide therapy have similar effects, however the adverse effects of systemic acetazolamide should be taken into account. Therefore it is better to prefer topical dorzolamide-timolol maleate combination therapy. K Ke ey y W Wo or rd ds s: : Phacoemulsification; intraocular pressure; acetazolamide; dorzolamide-timolol combination Ö ÖZ ZE ET T A Am ma aç ç: : Fakoemülsifikasyon cerrahisi sonrası artan göziçi basıncını azaltmak için kullanılan ağızdan verilen asetazolamid ile damla şeklinde uygulanan dorzolamid-timolol maleat kombinasyonunun etkinlik ve güvenilirliğinin kıyaslanmasıdır. G Ge er re eç ç v ve e Y Yö ön nt te em ml le er r: : Kataraktı olan ve fakoemülsifikasyon ve göziçi mercek (GİM) implantasyon cerrahisi geçiren 67 (33 erkek, 34 kadın) hastanın 67 gözü retrospektif olarak değerlendirildi. Hastalar iki gruba ayrıldılar. 1. grup 33 (%49) hastadan oluşmaktaydı, bu gruptaki hastalara ameliyattan 1 saat önce ve 1 saat sonra ağızdan 250 mg asetazolamid (toplam 500 mg) verildi ve ameliyattan sonraki 3 gün boyunca da 125 mg asetazolamid 3x1 önerildi. 2. grup 34 (%51) hastadan oluşmaktaydı, bu gruptaki hastalara ameliyattan 1 saat önce 1 damla dorzolamid-timolol maleat kombinasyonu uygulandı ve ameliyattan sonraki 3 gün boyunca da damla şeklinde dorzolamid-timolol maleat kombinasyonu 2x1 şek-linde önerildi. B Bu ul lg gu ul la ar r: : 1. grubun ortalama ameliyat öncesi göziçi basınç değeri 14,60±3,21 (SD)...

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“…[20][21][22][23] In our study, the effectiveness of dorzolamide-timolol maleate combination was not different from that of oral acetazolamide.…”

Section: Discussioncontrasting

confidence: 40%

Section: Resultsmentioning

confidence: 97%

Section: Comparison Of Efficacy and Safety Of Topical Dorzolamide-timmentioning

confidence: 95%

See 1 more Smart Citation

Comparison of Efficacy and Safety of Topical Dorzolamide-Timolol Maleate Combination with Oral Acetazolamide for Prevention of Intraocular Pressure Rise Following Phacoemulsification Surgery

Çetinkaya¹,

Akçam²,

Gürdağ³

et al. 2015

Turkiye Klinikleri J Ophthalmol

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“…Hipertensão ocular é uma complicação reconhecida após cirurgia de catarata, mesmo quando realizada sem complicações ou intercorrências per-operatórias (10,11) . A diminuição das propriedades biomecânicas da córnea está relacionada a dificuldade na capacidade de detectar o aumento da PIO (12,14) .…”

Section: Discussionunclassified

Avaliação da pressão intraocular através do ocular response analyzer antes e após cirurgia de facoemulsificação

Valbon¹,

Silva²,

Jardim³

et al. 2011

Rev. bras.oftalmol.

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“…1,4 The problem with the vast majority of the studies that have investigated prophylaxis regimes for a raised IOP is that they have excluded patients suffering with glaucoma or OHT. [8][9][10][11][12][13][14][15][16][17][18][19] It is of importance to study such regimes specifically in glaucoma and OHT populations, as it is these patients who are most at risk of a raised IOP. 6,12,20 It has been suggested that this pressure rise may be transient postoperatively.…”

Section: Introductionmentioning

confidence: 99%

Is the 1-day postoperative IOP check needed post uncomplicated phacoemulsification in patients with glaucoma and ocular hypertension?

Gupta

Vernon

2015

Eye

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Purpose To determine whether the 1-day postoperative intraocular pressure (IOP) check following routine uncomplicated phacoemulsification is necessary in patients with pre-existing glaucoma and ocular hypertension (OHT), if acetazolamide prophylaxis is used. To investigate the practice of UK glaucoma specialists in IOP rise prophylaxis and follow-up regimes.Patients and methods The IOP 1-day postoperatively was analysed against the last recorded IOP before phacoemulsification in a cohort of patients with glaucoma or OHT who underwent uncomplicated phacoemulsification cataract surgery between December 2009 and September 2012, where it was routine practice to give acetazolamide postoperatively. UK and Eire Glaucoma Society members were surveyed via an online questionnaire to analyse practice among UK glaucoma specialists. Results One hundred and seven eyes were studied: 99 with glaucoma and 8 with OHT. The mean IOP change was À 0.8 mm Hg with only two eyes measuring 430 mm Hg postoperatively (2%). Both these eyes received 750 mg acetazolamide. Eighteen (17%) eyes had an IOP rise of at least 30%. In the survey of practice there were 65 respondents. Twenty-one (32%) respondents did not use IOP prophylaxis. Only 17 (26%) of respondents routinely reviewed their patients 1-day postoperatively.Conclusion Our prophylactic acetazolamide regime does not completely eliminate the risk of an IOP 430 mm Hg on day 1 post routine phacoemulsification in glaucoma/ OHT patients. Patients with pre-existing glaucoma, despite acetazolamide prophylaxis, will require IOP management decisions on the first postoperative day after uncomplicated phacoemulsification surgery. UK expert practice is non-uniform with regard to IOP prophylaxis, and the 1-day review, and further discussion and formulation of consensus appears necessary.

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Medical control of intraocular pressure after phacoemulsification

Abstract: Brinzolamide was as effective as acetazolamide in preventing IOP elevation 4 to 6 hours after phacoemulsification and more effective than acetazolamide at 18 to 24 hours.

Cited by 42 publications

References 15 publications

Comparison of Efficacy and Safety of Topical Dorzolamide-Timolol Maleate Combination with Oral Acetazolamide for Prevention of Intraocular Pressure Rise Following Phacoemulsification Surgery

Comparison of Efficacy and Safety of Topical Dorzolamide-Timolol Maleate Combination with Oral Acetazolamide for Prevention of Intraocular Pressure Rise Following Phacoemulsification Surgery

Avaliação da pressão intraocular através do ocular response analyzer antes e após cirurgia de facoemulsificação

Is the 1-day postoperative IOP check needed post uncomplicated phacoemulsification in patients with glaucoma and ocular hypertension?

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