Medical Applications for 3D Printing

Mills, David K.; Tappa, Karthik; Jammalamadaka, Uday; Mills, Patrick; Alexander, Jonathan; Weisman, Jeffery A.

doi:10.1201/b22020-8

Cited by 7 publications

(6 citation statements)

References 1 publication

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“…The clinical method for treating bacterial infections requires high-dose and long-term systemic antibiotics administration, which may lead to systemic toxicity and antibiotic resistance. [117,118] Therefore, it is highly desirable to develop antibiotic-free therapeutic strategies for bacterial infections. As an emerging technology, SDT also shows unique potential in anti-bacteria and treatment of infectious diseases.…”

Section: Anti-bacteriamentioning

confidence: 99%

Piezotronic and piezo‐phototronic effects on sonodynamic disease therapy

Zhao

Huang

Zhang

et al. 2023

BMEMat

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With the development of engineered nanomaterials and nanomedicines, utilization of nanomaterials to generate excessive reactive oxygen species under exogenous ultrasound (US) irradiation for realizing disease therapy, namely sonodynamic therapy (SDT), has attracted widespread attention. Compared with traditional photodynamic therapy, US shows deeper tissue penetration to reach deep-seated location. However, the development of high-efficiency sonosensitizers remains one of the gravest challenges in current related research and future clinical application. Latterly, benefiting from the piezotronic and piezo-phototronic effects, novel sonosensitizers based on piezoelectric semiconductor (PS) nanomaterials have exhibited inspiring application prospects in SDT. In this review, we outline the structures and physicochemical properties of PS nanomaterials that has potential applications in SDT, and introduce the presumed mechanisms of PS nanomaterials in SDT. Then, the latest research progress of PS nanomaterials as sonosensitizers in cancer therapy and antibacterial applications are summarized. Finally, the existing challenges and future development trends in this field are prospected.

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Section: Anti-bacteriamentioning

confidence: 99%

Piezotronic and piezo‐phototronic effects on sonodynamic disease therapy

Zhao

Huang

Zhang

et al. 2023

BMEMat

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“…Regarding potential infections owing to chronic osteomyelitis during the bone repair process, treatment of osteomyelitis is crucial to the guarantee of lower recurrence of osteosarcoma. 300 Osteomyelitis, the bacterial infection of bone or bone marrow occurring in an open fracture, has always been a major clinical challenge. 301 Methicillin-resistant Staphylococcus aureus is the most common pathogen of osteomyelitis, which can cause bone destruction at the infection site by inducing osteoblast apoptosis, activating the generation of osteoclast and secreting toxins.…”

Section: Disease Treatmentmentioning

confidence: 99%

Engineering single-atom catalysts toward biomedical applications

Chang

Zhang

et al. 2022

Chem. Soc. Rev.

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“…Biocompatibility of printing materials depends on two factors: cytotoxicity and biodegradability, which means that the printing materials have to be safe from any possible damage to cell and can be decomposed into smaller metabolizable substances without any immune response. [180][181][182] The most common biocompatible materials among many metals and alloys are stainless steel and titanium, which can be used in metal 3D printing. Most of natural polymers, such as silk fibroin and chitosan, are well-known for their excellent biocompatibility in supporting cellular proliferation and can be used to print biomedical device.…”

Section: Biomedical Sensorsmentioning

confidence: 99%

“…Most of natural polymers, such as silk fibroin and chitosan, are well-known for their excellent biocompatibility in supporting cellular proliferation and can be used to print biomedical device. [180,181] Besides, the biocompatibility of printing material can be improved by some post-printing treatments, such as UV light or chemical solvent. For example, Tzivelekis et al reported a 3D printed biodevice for nucleic acid amplification by using a high-resolution and low-cost DLP-SLA printing method (Figure 7c).…”

Section: Biomedical Sensorsmentioning

confidence: 99%

Recent Advances in 3D Printed Sensors: Materials, Design, and Manufacturing

Jiang

Islam

et al. 2022

Adv Materials Technologies

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Market research shows that the global 3D printing market size was $16.54 billion in 2021 and is expected to have a growth rate of 21.0% from 2021 to 2028. The global market will reach around $63 billion by 2028. [1] 3D printing has been used in different environments ranging from ambient home and office use, bioimplant printing, to zero gravity space 3D printing, such as functional living organism's body parts, [2] and zero-gravity 3D printing in the international space station. [3] Apart from lab printing of delicate designs, 3D printing technology is being used for industrial [4] and construction [5] purposes. It has gained research and industrial interests in broad areas, including biomedical applications, [6,7] lightweight engineering materials, [7][8][9][10] electronics and sensors, [11] fiber-reinforced and multifunctional composites, [8,9,[12][13][14][15][16][17] and shape morphing designs. [6,18] Among different 3D printed devices, 3D printed sensors have been attracting significant attention. In sensors manufacturing, it is important for 3D printing of complementary accessories, embedded sensing components, as well as seamless fabrication of whole sensors [19] .Traditional manufacturing methods, such as coating and injection molding, are incompatible for fabricating complex structured sensors.

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Medical Applications for 3D Printing

Cited by 7 publications

References 1 publication

Piezotronic and piezo‐phototronic effects on sonodynamic disease therapy

Piezotronic and piezo‐phototronic effects on sonodynamic disease therapy

Engineering single-atom catalysts toward biomedical applications

Recent Advances in 3D Printed Sensors: Materials, Design, and Manufacturing

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