Mediating effects on health-related quality of life in adults with osteoporosis: a structural equation modeling

Huang, Chiung‐Yu; Liao, Lulu; Tong, Katherine; Lai, Hui‐Ling; Chen, W.-K.; Chen, C.-I.; Lu, Chu-Yun; Chen, F.-J.

doi:10.1007/s00198-014-2963-3

Cited by 21 publications

(18 citation statements)

References 29 publications

(59 reference statements)

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“…(93) Moreover, failure to meet patients' educational needs (eg, medication, self-management, the nature of osteoporosis) has been associated with poor treatment adherence, deterioration of the doctor-patient relationship, and important negative psychosocial consequences. Providing osteoporosis patients with adequate informational support has been shown to be critical to their health-related quality of life.…”

Section: Fundamental Recommendations and Rationalesmentioning

confidence: 99%

“…(20,97,99) Theoretically, identifying and addressing these factors could reduce the risk of secondary fracture. (92,93) Clinicians nevertheless need to consider the possibility of secondary causes of osteoporosis, conduct an appropriate history and medical examination, and consider referring patients with possible secondary causes to appropriate subspecialists. (92,93) Clinicians nevertheless need to consider the possibility of secondary causes of osteoporosis, conduct an appropriate history and medical examination, and consider referring patients with possible secondary causes to appropriate subspecialists.…”

Section: Additional Recommendations and Rationalesmentioning

confidence: 99%

“…Providing osteoporosis patients with adequate informational support has been shown to be critical to their health-related quality of life. (93) Moreover, failure to meet patients' educational needs (eg, medication, self-management, the nature of osteoporosis) has been associated with poor treatment adherence, deterioration of the doctor-patient relationship, and important negative psychosocial consequences. (33) Explore and address any issues with treatment plan adherence that arise.…”

Section: Recommendationmentioning

confidence: 99%

See 2 more Smart Citations

Secondary Fracture Prevention: Consensus Clinical Recommendations from a Multistakeholder Coalition

Conley

Adib²,

Adler

et al. 2019

Journal of Bone and Mineral Research

168

111

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Osteoporosis‐related fractures are undertreated, due in part to misinformation about recommended approaches to patient care and discrepancies among treatment guidelines. To help bridge this gap and improve patient outcomes, the American Society for Bone and Mineral Research assembled a multistakeholder coalition to develop clinical recommendations for the optimal prevention of secondary fracture among people aged 65 years and older with a hip or vertebral fracture. The coalition developed 13 recommendations (7 primary and 6 secondary) strongly supported by the empirical literature. The coalition recommends increased communication with patients regarding fracture risk, mortality and morbidity outcomes, and fracture risk reduction. Risk assessment (including fall history) should occur at regular intervals with referral to physical and/or occupational therapy as appropriate. Oral, intravenous, and subcutaneous pharmacotherapies are efficacious and can reduce risk of future fracture. Patients need education, however, about the benefits and risks of both treatment and not receiving treatment. Oral bisphosphonates alendronate and risedronate are first‐line options and are generally well tolerated; otherwise, intravenous zoledronic acid and subcutaneous denosumab can be considered. Anabolic agents are expensive but may be beneficial for selected patients at high risk. Optimal duration of pharmacotherapy is unknown but because the risk for second fractures is highest in the early post‐fracture period, prompt treatment is recommended. Adequate dietary or supplemental vitamin D and calcium intake should be assured. Individuals being treated for osteoporosis should be reevaluated for fracture risk routinely, including via patient education about osteoporosis and fractures and monitoring for adverse treatment effects. Patients should be strongly encouraged to avoid tobacco, consume alcohol in moderation at most, and engage in regular exercise and fall prevention strategies. Finally, referral to endocrinologists or other osteoporosis specialists may be warranted for individuals who experience repeated fracture or bone loss and those with complicating comorbidities (eg, hyperparathyroidism, chronic kidney disease). © 2019 American Society for Bone and Mineral Research.

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Section: Fundamental Recommendations and Rationalesmentioning

confidence: 99%

Section: Additional Recommendations and Rationalesmentioning

confidence: 99%

Section: Recommendationmentioning

confidence: 99%

See 1 more Smart Citation

Secondary Fracture Prevention: Consensus Clinical Recommendations from a Multistakeholder Coalition

Conley

Adib²,

Adler

et al. 2019

Journal of Bone and Mineral Research

168

111

View full text Add to dashboard Cite

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“…Low social support and low socioeconomic status significantly increased the odds of depressive symptoms[14]. Better social support is reported to be associated with improved QOL, and individuals with OP who have lower pain and more exercise are considered having better QOL[15]. Social support predicts QOL above and beyond disease activity, demographic factors and social integration in patients with rheumatoid arthritis[16], and measurement of QOL plays an important role in the clinical evaluation of OP and comparison of different therapeutic measures in clinical trials[17,18].…”

Section: Introductionmentioning

confidence: 99%

Quality of Life Is Related to Social Support in Elderly Osteoporosis Patients in a Chinese Population

Wang

et al. 2015

PLoS ONE

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ObjectiveTo explore the association between quality of life and social support in elderly osteoporosis patients in a Chinese population.MethodsA total of 214 elderly patients who underwent bone mineral density screening were divided into two groups: elderly patients with primary osteoporosis (case group, n = 112) and normal elderly patients (control group, n = 102). Quality of life and social support were compared between the two groups.ResultsQuality of life and social support were significantly different between the case and control groups. The physical function, role-physical, bodily pain, general health, vitality, social-functioning, role-emotional and mental health scores in case group were significantly lower than those in the control group (P < 0.01). The objective support, subjective support, utilization of support, and total scores in case group were significantly lower than those in the control group (P < 0.01). Quality of life and social support were positively correlated in the case group (r = 0.672, P < 0.01).ConclusionQuality of life and social support in elderly patients with osteoporosis in China were poorer than in elderly patients without osteoporosis and were positively correlated. Our findings indicate that increased efforts to improve the social support and quality of life in elderly osteoporosis patients are urgently needed in China. Further longitudinal studies should be conducted to provide more clinical evidence to determine causative factors for the observed association between risk factors and outcomes.

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“…The last variable which was positively influencing HRQoL was the presence of family member who reminds and supports the patient to take the medications. Better social support has been reported to be associated with improved HRQoL . The HRQoL in elderly with osteoporosis might be increased if they are encouraged to spend more time with family and friends, actively participate in collective activities, and actively talk to family members or friends when encountering troubles or are confused with something …”

Section: Discussionmentioning

confidence: 99%

Health‐related quality of life and its associated factors among outpatients with osteoporosis

Jarab

Mukattash

Hilan

et al. 2019

J Pharm Health Serv Res

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Objective The study aim was to evaluate health‐related quality of life (HRQoL) and to explore factors associated with poor HRQoL in patients with osteoporosis in Jordan. Methods The validated EQ‐5D questionnaire was used to assess HRQoL in outpatients with osteoporosis at the Royal Medical Services Hospital in Jordan. The EQ‐5D is a standardised instrument that has been widely used in clinical studies for evaluating generic health status. Sociodemographic and medical data were collected using custom‐designed questionnaire and hospital medical files. Multiple logistic regression analysis was performed to build a model with variables associated with poor HRQoL. Key findings The mean score of the total EQ‐5D index of the 296 participants was 0.620. Most of the participants reported ‘some problems’ through the five dimensions, with the highest percentage (72.3%) related to pain/discomfort domain. Regression analysis identified serum vitamin D level (OR = 0.942; CI = 0.891–0.996), number of current medications (OR = 1.273; CI = 1.015–1.597), having movement restriction (OR = 2.525; CI = 1.131–5.638), having spine kyphosis (OR = 5.746; CI = 1.796–18.386) and the presence of friend or family member to remind the patient to take the medications (OR = 3.364; CI = 1.394–8.114) as being significantly associated with poor HRQoL. Conclusion The HRQoL has considerable scope for improvement in patients with osteoporosis in the present study. Future osteoporosis management programmes should focus on improving HRQoL with specific attention to be given for patients with low serum vitamin D level, patients receiving multiple medications, patients having movement restriction, patients having spine kyphosis and those who have no friend or family member to remind them to take the medication.

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Mediating effects on health-related quality of life in adults with osteoporosis: a structural equation modeling

Cited by 21 publications

References 29 publications

Secondary Fracture Prevention: Consensus Clinical Recommendations from a Multistakeholder Coalition

Secondary Fracture Prevention: Consensus Clinical Recommendations from a Multistakeholder Coalition

Quality of Life Is Related to Social Support in Elderly Osteoporosis Patients in a Chinese Population

Health‐related quality of life and its associated factors among outpatients with osteoporosis

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