Mediastinal radioiodine uptake due to hiatal hernia: a false-positive reason in 131I scan

Günay, Emel Ceylan; Erdoğan, A.

doi:10.1016/j.remn.2009.11.007

Cited by 10 publications

(2 citation statements)

References 2 publications

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“…The authors reported 2 examples of unusual false-positive I-131 whole-body scan findings in papillary thyroid carcinoma caused by chronic sialadenitis of a submandibular gland and a maxillary mucous retention cyst (8). Increased superﬁcial I-131 uptake in the left calf suggesting contamination was reported to be a dilated left greater saphenous vein by a prior study in an interesting image report (9). Mediastinal radioiodine uptake due to hiatal hernia was also reported by another study as one of the false positive findings in radioiodine scans (10).…”

Section: Discussionmentioning

confidence: 84%

Radioiodine Contamination Artifacts and Unusual Patterns of Accumulation in Whole-body I-131 Imaging: A Case Series

Kara

Günay

Erdoğan

2014

Int J Endocrinol Metab

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Introduction:Radioactive iodine has been used for more than 50 years for the treatment of thyroid diseases. Differentiated thyroid cancers have the ability to trap iodine. Therefore, radioiodine can be used both diagnostically and therapeutically. In the follow-up of patients, it is critical to interpret radioiodine scans correctly.Case Presentation:Non-physiological Iodine-131 (I-131) extra-thyroidal uptake detected on post-therapy or diagnostic I-131 scanning are not always interpreted as functioning metastatic thyroid cancer.Conclusions:This study provides detailed information and case samples of radiodine contamination artifacts and non-physiological, non-metastatic extra-thyroidal I-131 accumulation in whole-body I-131 imaging.

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Section: Discussionmentioning

confidence: 84%

Radioiodine Contamination Artifacts and Unusual Patterns of Accumulation in Whole-body I-131 Imaging: A Case Series

Kara

Günay

Erdoğan

2014

Int J Endocrinol Metab

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“…[ 6 ] There are occasional reports of a hiatal hernia demonstrating thoracic uptake on I-131 scintigraphy. [ 7 8 ] This is a cause of a potential false-positive appearance mimicking a pulmonary or mediastinal metastasis. The etiology of this finding is justified by the retention of radioiodinated body fluids (saliva, tears, blood, urine, exudate, transudate, gastric, mucosal secretions, etc.…”

Section: Discussionmentioning

confidence: 99%

Hiatal hernia uptake of iodine-131 mimicking mediastinal metastasis of papillary thyroid carcinoma

Haghighatafshar

Khajehrahimi

2015

Indian J Nucl Med

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There are a few case reports of hiatal hernia demonstrating thoracic uptake on I-131 scintigraphy. In this case, high thyroglobulin levels in combination with misinterpretation of I-131 uptake in the mediastinum, leaded to mismanagement of the patient. Here we present a case of focal I-131 uptake within a hiatal hernia initially mimicking an isolated mediastinal metastasis. There are many potential causes of false-positive I-131 scan result. In this case, adjunctive chest computed tomography and gastroesophageal barium study helped to elucidate the true nature of this I-131 uptake. False-positive findings may be caused by a wide variety of nonthyroidal carcinomas, which can concentrate radioiodine or from skin contamination. Several organs, such as the gastric, salivary glands, renal cyst, pericardial effusion, and ovarian can accumulate I-131. It should be borne in mind as a potential source of false-positive whole-body I-131 imaging.

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False-Positive Radioiodine Scans in Thyroid Cancer

Shapiro¹,

Rufini²,

Jarwan³

et al. 2016

Thyroid Cancer

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Mediastinal radioiodine uptake due to hiatal hernia: a false-positive reason in 131I scan

Cited by 10 publications

References 2 publications

Radioiodine Contamination Artifacts and Unusual Patterns of Accumulation in Whole-body I-131 Imaging: A Case Series

Radioiodine Contamination Artifacts and Unusual Patterns of Accumulation in Whole-body I-131 Imaging: A Case Series

Hiatal hernia uptake of iodine-131 mimicking mediastinal metastasis of papillary thyroid carcinoma

False-Positive Radioiodine Scans in Thyroid Cancer

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