Meconium Peritonitis with Intestinal Atresia Mimicking Huge Tumor in a Preterm Neonate

Lien, Chi-Hone; Chang, Hung‐Yang; Liu, Yu-Peng; Duh, Yih-Cherng; Lin, Chien‐Yu

doi:10.1016/j.jpeds.2012.08.028

Cited by 2 publications

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“…Rare causes of MP include colonic atresia, torsion of a fallopian tube cyst, and fetus in fetu. [1–4] After leakage of meconium into the peritoneal cavity, a secondary inflammatory response occurs. This secondary inflammatory response results in ascites, fibrosis, calcification, and occasionally cystic formation.…”

Section: Introductionmentioning

confidence: 99%

“…[2] Characteristic prenatal sonographic findings are fetal ascites, dilated intestinal loops, intra-abdominal calcifications, echogenic bowel, polyhydramnios, and pseudocysts. [4–8] Postnatally, it has a wide range of presentations from asymptomatic with sealed-off peritonitis to severe peritonitis requiring emergent surgery. [5] The most common postnatal manifestations include respiratory distress, abdominal distention, bilious vomiting, and delayed meconium passage.…”

Section: Introductionmentioning

confidence: 99%

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Value of prenatal diagnosis of meconium peritonitis

et al. 2019

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Advancements in diagnostic modalities have improved the diagnosis of meconium peritonitis (MP) both in utero and ex utero. This study aimed to determine the efficacy of prompt prenatal and postnatal diagnoses of MP on the postnatal outcomes of these patients.We conducted a retrospective chart review of neonates with MP admitted to the Mackay Memorial Hospital Systems from 2005 to 2016. The prenatal diagnoses, postnatal presentations, surgical indications, operative methods, types of MP, operative findings, associated anomalies, morbidities, patient outcomes, and survival rates were analyzed. Morbidities included postoperative adhesion ileus, bacteremia, and short bowel syndrome. We also performed subgroup analyses of the morbidity and survival rates of prenatally versus postnatally diagnosed patients, as well as inborn versus outborn neonates.Thirty-seven neonates with MP were enrolled. Of this number, 24 (64.9%) were diagnosed prenatally. Twenty-two (59.5%) were born preterm. The most common prenatal sonographic findings included fetal ascites followed by dilated bowel loops. Abdominal distention was the most frequent postnatal symptom. Thirty-four (91.9%) neonates underwent surgery, whereas 3 were managed conservatively. Volvulus of the gastrointestinal tract was the most frequent anatomic anomaly. The total morbidity and survival rates were 37.8% and 91.9%, respectively. The morbidity and survival rates did not differ significantly between prenatally and postnatally diagnosed patients (37.5% vs 33.3%, P = 1.00; 91.7% vs 92.3%, P = 1.00, respectively). Inborn and outborn patients did not differ in terms of morbidity and survival rates (27.3% vs 53.3%, P = .17; 100% vs 80.0%, P = .06, respectively).Although not statistically significant, inborn MP neonates had higher survival rates when compared with outborn MP neonates. Prompt postnatal management at tertiary centers seemed crucial.

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Section: Introductionmentioning

confidence: 99%