Mechanochromic luminescent covalent organic frameworks for highly selective hydroxyl radical detection

Abstract

The mechanochromic luminescence phenomenon was first reported in the low-cost mechanochemical (MC) synthesis process of a covalent organic framework (COF-TpMA (MC)) which shows excellent performance as a hydroxyl radical detector in living systems.

BODIPY-Decorated Nanoscale Covalent Organic Frameworks for Photodynamic Therapy

“…As a promising alternative to MOFs, metal-free covalent organic frameworks (COFs) (Bisbey and Dichtel, 2017, Lohse and Bein, 2018) should be more biocompatible and suitable for biomedical treatment because of their pure organic nature (Figure S1, see Normal Tissue Cytotoxicity Test in Transparent Methods for experimental details) (Guan et al., 2018b, Jiang et al., 2019, Ruyra et al., 2015, Tamames-Tabar et al., 2014). Some examples of COF-based biomedical applications have been reported, such as fluorescence bioimaging (Das et al., 2018, Li et al., 2017, Liu et al., 2019b, Wang et al., 2018a), drug delivery (Bai et al., 2016, Fang et al., 2015, Liu et al., 2019a, Mitra et al., 2017, Vyas et al., 2016b, Zhang et al., 2018b), antibacterial therapy (Hynek et al., 2018, Liu et al., 2017, Mitra et al., 2016), enzyme immobilization (Kandambeth et al., 2015, Sun et al., 2018c), biochemical analysis (Liu et al., 2019c, Yan et al., 2019, Zhang et al., 2018e, Zhang et al., 2018f, Zhou et al., 2019), and so on. In addition, some conceptual therapeutic models, such as 1 O 2 generation (Feng et al., 2016, Lin et al., 2017, Nagai et al., 2013), photothermal conversion (Tan et al., 2016), and apoptosis induction (Bhanja et al., 2017), have also been reported.…”

Porous Organic Polymers Containing a Sulfur Skeleton for Visible Light Degradation of Organic Dyes

“…Figure S1 (right, in the Supporting Information) is the 13 C NMR spectrum of TpMD. The signal at δ ≈130.5 ppm (peak 6) can be attributed to the formation of C=N, and the other important signals are also labeled . As shown in Figures S2 (left) and S3 (left, in the Supporting Information), the stretching vibration bands at 1577 cm −1 and 1610 cm −1 represent the C−S of thioether (TpTD), and the stretching vibration bands at 1300 cm −1 and 1150 cm −1 represent the S=O characteristic signals of sulfone (TpSD).…”

“…The signal at d % 130.5 ppm (peak 6) can be attributed to the formation of C=N, and the other important signals are also labeled. [26] As shown in Figures S2 (left) and S3 (left, in the Supporting Information), the stretching vibration bands at 1577 cm À1 and 1610 cm À1 represent the CÀSo ft hioether (TpTD), and the stretching vibration bands at 1300 cm À1 and 1150 cm À1 represent the S=Oc haracteristics ignals of sulfone (TpSD). The signals of C=Ni nt he 13 CNMR spectra of TpTD and TpSD are varied compared with TpMD.…”

Nanoscale covalent organic frameworks as theranostic platforms for oncotherapy: synthesis, functionalization, and applications

“…The mechanochemical synthesis of COFs is still at a vigorously developing stage. The advantage of space-time yield overwhelms the lack of relatively high crystallinity, and the resulting COFs have been applied in the elds of separation, 141 detection, 142 and electrochemistry. 143,144…”