Purpose. Determination the impact of duration of mechanochemical activation on enhancement of zinc leaching from poly metallic ore tailings to ensure the sustainable mining.Methodology. In experimental studies on the mechanical activation of geomaterial from the tails of Sadon polymetallic ores, the DESI11 disintegrator was used. As a solution for leaching, a mixture with a different ratio of mass concentrations of hydro chloric and sulfuric acids was used. In addition, the ratio of solid and liquid fractions was varied from 1/4 to 1/10 with process duration of 15 to 60 minutes. The results were processed by the standard LOESS method in combination with threedimensional interpolation of an incomplete data sample.findings. Polynomial dependences have been established that make it possible to calculate the degree of zinc extraction from the tail, depending on the parameters of the process of the leached solution, the ratio of the solid and liquid phases in the pulp and the duration of agitation leaching. originality. For the first time, the mechanism of surface transformation, size and location of zones with maximum leaching efficiency with small changes in the duration of mechanical activation of the pulp was clarified.Practical value. The revealed patterns can be used to optimize the parameters of agitation leaching by correlating the cost of energy consumption for increasing the duration of the process and unit costs for the lixiviants.