Mechanisms underlying the association between insomnia, anxiety, and depression in adolescence: Implications for behavioral sleep interventions

Blake, Matthew; Trinder, John; Allen, Nicholas

doi:10.1016/j.cpr.2018.05.006

Cited by 273 publications

(213 citation statements)

References 244 publications

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“…They have also, on occasion, been referred to as neurodevelopmental disorders, especially schizophrenia [13,14], as they involve difficulties in the execution of intellectual, motor, language, or social functions as well as other domains that arise from alterations in brain circuits. Similar to the definition of neurodevelopmental disorders in the ICD-11, the presumptive etiology of mood disorders in childhood and adolescence, for example, is also 'complex' and is thought to arise from 'physical' processes (inflammatory processes, chronic sleep disturbance, possibly the microbiome) and genetic factors [15][16][17] as well as from various types of stressful life events. The growing awareness of the comorbidity of mood and anxiety disorders with various neurodevelopmental disorders (once the children reach adolescence) is another indication that the boundary between neurodevelopmental and non-neurodevelopmental disorders in the ICD-11 is ambiguous.…”

Section: Introductionmentioning

confidence: 99%

Mental, behavioral and neurodevelopmental disorders in the ICD-11: an international perspective on key changes and controversies

Stein

Szatmári

Gäebel

et al. 2020

BMC Med

162

121

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An update of the chapter on Mental, Behavioral and Neurodevelopmental Disorders in the International Classification of Diseases and Related Health Problems (ICD) is of great interest around the world. The recent approval of the 11th Revision of the ICD (ICD-11) by the World Health Organization (WHO) raises broad questions about the status of nosology of mental disorders as a whole as well as more focused questions regarding changes to the diagnostic guidelines for specific conditions and the implications of these changes for practice and research. This Forum brings together a broad range of experts to reflect on key changes and controversies in the ICD-11 classification of mental disorders. Taken together, there is consensus that the WHO's focus on global applicability and clinical utility in developing the diagnostic guidelines for this chapter will maximize the likelihood that it will be adopted by mental health professionals and administrators. This focus is also expected to enhance the application of the guidelines in non-specialist settings and their usefulness for scaling up evidence-based interventions. The new mental disorders classification in ICD-11 and its accompanying diagnostic guidelines therefore represent an important, albeit iterative, advance for the field.

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Section: Introductionmentioning

confidence: 99%

Mental, behavioral and neurodevelopmental disorders in the ICD-11: an international perspective on key changes and controversies

Stein

Szatmári

Gäebel

et al. 2020

BMC Med

162

121

View full text Add to dashboard Cite

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“…This disparity between participants with clinical and subclinical insomnia may be explained by the relationship between trait anxiety and the appraisal of stress. Highly anxious individuals may be more likely to remember negative events or to evaluate their experience negatively, which may induce subclinical insomnia in the absence of a stressor [30]. Moreover, our findings suggest that trait anxiety is more related to transient insomnia than to persistent insomnia in the absence of precipitating stressors.…”

Section: Discussionmentioning

confidence: 66%

Depression and Anxiety Associated with Insomnia and Recent Stressful Life Events

et al. 2019

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“…The observed distributions in the insomnia were summarized in de ned groups based on the scores from ISI as follows: none (0-7), mild (8)(9)(10)(11)(12)(13)(14), moderate (15)(16)(17)(18)(19)(20)(21), severe (22)(23)(24)(25)(26)(27)(28). Depression was rate on PHQ-9 of ve levels: none (0-4), mild (5-9), moderate (10)(11)(12)(13)(14), moderatesevere (15)(16)(17)(18)(19) severe (20)(21)(22)(23)(24)(25)(26)(27). Anxiety was graded according to the score of the GAD-7: none (0-4), mild (5-9), moderate (10-13), moderate-severe (14-18), severe (19)(20)(21).…”

Section: Discussionmentioning

confidence: 99%

“…Doctors must manage patients' expectations while working with them to optimize sleep quality. Several 'biopsychosocial' mechanisms hold promise as possible treatment targets for sleep interventions to reduce both insomnia and symptoms [26]. Cognitive behavior therapy were both effective at reducing insomnia and depression severity for older adults.…”

Section: Discussionmentioning

confidence: 99%

Insomnia is Associated with Depression and Anxiety in Patients Undergoing Noncardiac Surgery

Huang

Chen

Wang

et al. 2020

Preprint

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BackgroundTo investigate the difference of demographic, health status and clinical characteristics of patients with or without insomnia postoperatively, and to identify the potential risk factors of insomnia.Methods299 patients undergoing surgery were included. Patients were divided into group A (insomnia, N = 78) and group B (without insomnia, N = 221). Insomnia Severity Index (ISI), Patient Health Questionnaire-9 (PHQ-9), Generalized Anxiety Disorder (GAD-7), and Montreal cognitive assessment (MoCA) were applied to all patients preoperatively. Visual Analogue Scale (VAS) was assessed preoperatively, and at the end of the surgery, one day after surgery, two days after surgery and three days after surgery. The PHQ-9, the GAD-7 and the ISI were reassessed three days after surgery. Information on sociodemographic variables and demographic data were collected.ResultsAmong the two groups, the average points patients got in the ISI, PHQ-9 and the GAD-7 in group A were also significantly higher than those in group B. The VAS score 3 days after surgery was significantly higher in group A. The PHQ-9 and the GAD-7 3 days after surgery showed significantly higher depression and anxiety scores in group A. Logistic regression showed ISI (P < 0.001, 95%CI = 1.218-1.500), the GAD-7 (P = 0.01, 95%CI = 0.712–0.954) preoperatively and the PHQ-9 postoperatively (P < 0.001, 95%CI = 1.226–1.555) were risk factors of insomnia.ConclusionsInsomnia is common in patients, which worsen after surgery. The present study suggests that depression and anxiety are risk factors of poor sleep quality after surgery. There is a need for further research and strategies for depression and anxiety management to achieve better sleep and significant health benefits in these patients.Trial registration: clinical trial, NCT04027751. Registered 22 July 2019, https://clinicaltrials.gov/ct2/show/NCT04027751?cond=NCT04027751&cntry=CN&draw=2&rank=1.

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Mechanisms underlying the association between insomnia, anxiety, and depression in adolescence: Implications for behavioral sleep interventions

Cited by 273 publications

References 244 publications

Mental, behavioral and neurodevelopmental disorders in the ICD-11: an international perspective on key changes and controversies

Mental, behavioral and neurodevelopmental disorders in the ICD-11: an international perspective on key changes and controversies

Depression and Anxiety Associated with Insomnia and Recent Stressful Life Events

Insomnia is Associated with Depression and Anxiety in Patients Undergoing Noncardiac Surgery

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