Mechanisms and effects of ultrasound-assisted supercritical CO2 extraction

Dassoff, Erik Scott; Li, Yao Olive

doi:10.1016/j.tifs.2019.03.001

Cited by 63 publications

(23 citation statements)

References 50 publications

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“…Any substance at a temperature and pressure above its thermodynamic critical point is a supercritical fluid. Under these conditions, the properties of the fluids generate a high diffusivity and low viscosity of the solvents used to improve the process of transfer of the matter [120]. Due to this, the SFE methodology (Figure 4) has reported flavonoid extraction yields much higher than those used in other techniques [121].…”

Section: Supercritical Fluid Extractionmentioning

confidence: 99%

Conventional and Emerging Extraction Processes of Flavonoids

et al. 2020

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Flavonoids are a group of plant constituents called phenolic compounds and correspond to the nonenergy part of the human diet. Flavonoids are found in vegetables, seeds, fruits, and beverages such as wine and beer. Over 7000 flavonoids have been identified and they have been considered substances with a beneficial action on human health, particularly of multiple positive effects because of their antioxidant and free radical scavenging action. Although several studies indicate that some flavonoids have provident actions, they occur only at high doses, confirming in most investigations the existence of anti-inflammatory effects, antiviral or anti-allergic, and their protective role against cardiovascular disease, cancer, and various pathologies. Flavonoids are generally removed by chemical methods using solvents and traditional processes, which besides being expensive, involve long periods of time and affect the bioactivity of such compounds. Recently, efforts to develop biotechnological strategies to reduce or eliminate the use of toxic solvents have been reported, reducing processing time and maintaining the bioactivity of the compounds. In this paper, we review, analyze, and discuss methodologies for biotechnological recovery/extraction of flavonoids from agro-industrial residues, describing the advances and challenges in the topic.

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Section: Supercritical Fluid Extractionmentioning

confidence: 99%

Conventional and Emerging Extraction Processes of Flavonoids

et al. 2020

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“…Furthermore, SFE using CO 2 is adapted to the extraction of thermolabile compounds since it employs low temperatures, compared to other conventional techniques [115] . Overall, SFE offers several advantages over conventional extraction techniques, including enhanced extraction kinetics and improved extraction selectivity as well as the absence of solvent residue [116] . This technique presents yet some disadvantages such as low extraction yields and high cost compared to some conventional processes [116] .…”

Section: Us Coupled With Innovative Extraction Techniquesmentioning

confidence: 99%

“…Overall, SFE offers several advantages over conventional extraction techniques, including enhanced extraction kinetics and improved extraction selectivity as well as the absence of solvent residue [116] . This technique presents yet some disadvantages such as low extraction yields and high cost compared to some conventional processes [116] . Hence, US assistance may be useful in addressing these limitations.…”

Section: Us Coupled With Innovative Extraction Techniquesmentioning

confidence: 99%

Review of ultrasound combinations with hybrid and innovative techniques for extraction and processing of food and natural products

Khadhraoui

Ummat

Tiwari

et al. 2021

Ultrasonics Sonochemistry

126

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“…Sonication is a very effective method to fabricate or manipulate nano-and bio-materials in many applications [40]. High power ultrasounds can break-down chemical bonds depolymerizing macromolecules, downsizing particles to nanoscale, making nanoemulsions, extracting bioactive substances from different matrices and so on, in research laboratories, in pharmaceutical and agrifood industries [40][41][42][43]. Sonochemistry was recently investigated for synthesis of bioactive nanostructures [44], different nanocarriers such as niosomes [45], liposomes [46], nanoemulsions [47], solid lipid nanoparticles [48], metal based systems [49], polymeric particles [50], nanoclusters [51] and nanocomposites [43].…”

Section: Nanopesticides and Sonication Technologymentioning

confidence: 99%

Sonication-Assisted Production of Fosetyl-Al Nanocrystals: Investigation of Human Toxicity and In Vitro Antibacterial Efficacy against Xylella fastidiosa

Baldassarre

Tatulli²,

Vergaro

et al. 2020

Nanomaterials

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Recently, there is a growing demand in sustainable phytopathogens control research. Nanotechnology provides several tools such as new pesticides formulations, antibacterial nanomaterials and smart delivery systems. Metal nano-oxides and different biopolymers have been exploited in order to develop nanopesticides which can offer a targeted solution minimizing side effects on environment and human health. This work proposed a nanotechnological approach to obtain a new formulation of systemic fungicide fosetyl-Al employing ultrasonication assisted production of water dispersible nanocrystals. Moreover, chitosan was applicated as a coating agent aiming a synergistic antimicrobial effect between biopolymer and fungicide. Fosetyl-Al nanocrystals have been characterized by morphological and physical-chemical analysis. Nanotoxicological investigation was carried out on human keratinocytes cells through cells viability test and ultrastructural analysis. In vitro planktonic growth, biofilm production and agar dilution assays have been conducted on two Xylella fastidiosa subspecies. Fosetyl-Al nanocrystals resulted very stable over time and less toxic respect to conventional formulation. Finally, chitosan-based fosetyl-Al nanocrystals showed an interesting antibacterial activity against Xylella fastidiosa subsp. pauca and Xylella fastidiosa subsp. fastidiosa.

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Mechanisms and effects of ultrasound-assisted supercritical CO2 extraction

Cited by 63 publications

References 50 publications

Conventional and Emerging Extraction Processes of Flavonoids

Conventional and Emerging Extraction Processes of Flavonoids

Review of ultrasound combinations with hybrid and innovative techniques for extraction and processing of food and natural products

Sonication-Assisted Production of Fosetyl-Al Nanocrystals: Investigation of Human Toxicity and In Vitro Antibacterial Efficacy against Xylella fastidiosa

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