Mechanics of plasma exposed spin-on-glass (SOG) and polydimethyl siloxane (PDMS) surfaces and their impact on bond strength

Bhattacharya, Shantanu; Gao, Yuanfang; Korampally, Venumadhav; Othman, M.T.; Grant, Sheila; Gangopadhyay, Keshab; Gangopadhyay, Shubhra

doi:10.1016/j.apsusc.2006.09.028

Cited by 39 publications

(22 citation statements)

References 18 publications

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“…The bonding parameters are optimized using an algorithm developed by Bhattacharya et al (2006) For estimating an optimum bonding strategy the plasma dosages are varied and the surface hydrophilicity values are checked for different samples exposed to Oxygen plasma for different times (using surface contact angle). The contact angle values of various surfaces are measured and the time for which this goes below 10°is found.…”

Section: Design Of Electrodesmentioning

confidence: 99%

Dielectrophoresis assisted concentration of micro-particles and their rapid quantitation based on optical means

Ghubade

Mandal

Chaudhury

et al. 2009

Biomed Microdevices

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The detection and counting of micro particles having sizes comparable to biological entities can provide a tremendous impetus to rapid diagnostics and clinical applications. MEMS technology has already been used in capture and detection of such micron size entities in miniscule concentrations. For this purpose a concentration step is normally added prior to the detection process. A variety of methodologies are used for quantization of such micron size particles/entities including change in permittivity, medium impedance, magnetic permeability and other means. Although optical studies have been extensively performed prior to this, it has not been used for quantization of the micro particles. We have designed, developed and characterized a MEMS counter which captures micron size fluorescent beads using delectrophoresis (DEP) and monitors their accumulation in a 12 μm x 230 μm size channel and monitors this accumulation as growth of overall fluorescence. The field is generated by a set of finely placed interdigitated microelectrodes. As we apply an alternating voltage at 10 V(pp) for a range of different frequencies we are able to capture the flowing beads and concentrate them by several orders of magnitude. This is also followed by their quantification in terms of growing fluorescence signal. For quantitating the fluorescence values a CCD (charge couple device) module fitted over an inverted fluorescence microscope is used that visualizes the whole capture process and a Labview based image acquisition software simultaneously calculates the signal intensity over these frames and arranges it temporally. Our work will have tremendous utility in developing a rapid bacterial counting procedure and will be a valuable tool in microbiological laboratories.

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Section: Design Of Electrodesmentioning

confidence: 99%

Dielectrophoresis assisted concentration of micro-particles and their rapid quantitation based on optical means

Ghubade

Mandal

Chaudhury

et al. 2009

Biomed Microdevices

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“…18 Even though a freshly prepared NPS surface is more hydrophobic than bare Si (water contact angle > 95 ), 19 it is quite sensitive to air, and thus wafer annealing after NPS formation promotes growth of SiO2 on a top of the NPS substrate. The NPS surface formed by electrochemical anodization and subsequent annealing maintains hydrophilic property for a longer period of time than the conventional O2 plasma-based surface modification, 20 and has a relatively high surface free energy due to the increased hydrophilicity. 21 A macroporous silicon (MPS, pore diameter = 2 μm and pore depth = 10 μm) layer was unfavorable for direct deposition of PPy (Fig.…”

Section: Resultsmentioning

confidence: 99%

Label-free Electrochemical Detection of the Human Adenovirus 40/41 Fiber Gene

Song

Jin

2015

ANAL. SCI.

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A nanoporous silicon-based label-free DNA biosensor was fabricated to monitor rapidly enteric adenovirus types 40 and 41, a leading cause of viral gastroenteritis in children. Nanoporous silicon (NPS) was formed by an anodic etching process in a mixture solution containing hydrofluoric acid and ethanol. The polypyrrole (PPy) film was directly electropolymerized on The NPS substrate. Twenty-five base pairs of probe DNA (pDNA), derived from the fiber gene, was electrochemically doped on the PPy-coated NPS substrate. The conductivity change due to the immobilized pDNA and hybridized target DNA (tDNA) was expressed as an arbitrary factor, γ, which is a normalized numerical term used for the selective quantification of the tDNA. γ was inversely proportional to the concentration of complementary tDNA, but independent of the non-complementary tDNA. The sensitivity slope for detecting tDNAc was -1.54 μM -1 , based on the factor γ in the range of 0.4 to 1.0 μM of tDNA. The surface roughness was characterized using atomic force microscopy.

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“…The developing surface behaviour can be explained by the accumulation of the embedded molecules at the PDMS surface. The rapidly decreasing contact angle during the measurement indicates the increasing surface concentration of the modifying molecules at the PDMS / liquid interface [33,34,35]. The long term stability of the developed molecule layers were reported more than months by [11,12].…”

Section: Effect Of Surface Modification On Hydrophilicitymentioning

confidence: 97%

PDMS microfluidics developed for polymer based photonic biosensors

et al. 2014

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Abstract:In this work, advances in the fabrication technology and functional analysis of a polymer microfluidic system -as a significant part of a developed polymer photonic biosensor -are reported. Robust and cost-effective microfluidics in PDMS including sample preparation functions is designed and realized by using SU-8 moulding replica. Surface modification strategies using Triton X-100 and PDMS-PEO and their effect on device sealing and non-specific protein adsorption are investigated by contact angle measurement and in situ fluorescence microscopy.Response to Reviewers: Dear Editors and Reviewers, First of all, thank You for the effort in improving our paper. Regarding the reviewer comments, we made the following modifications regarding the latest version of the manuscript submitted. The modifications and the required supplements are submitted in pdf format with the revised manuscript.Thank You again for the efforts to improve our manuscript. Regards, Péter Fürjes

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Mechanics of plasma exposed spin-on-glass (SOG) and polydimethyl siloxane (PDMS) surfaces and their impact on bond strength

Cited by 39 publications

References 18 publications

Dielectrophoresis assisted concentration of micro-particles and their rapid quantitation based on optical means

Dielectrophoresis assisted concentration of micro-particles and their rapid quantitation based on optical means

Label-free Electrochemical Detection of the Human Adenovirus 40/41 Fiber Gene

PDMS microfluidics developed for polymer based photonic biosensors

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